Gene Information

Name : LAF_0066 (LAF_0066)
Accession : YP_001842882.1
Strain : Lactobacillus fermentum IFO 3956
Genome accession: NC_010610
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 85598 - 86896 bp
Length : 1299 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGACATCAAGCAAATTCGCCAACAACCGGACTGGTTCAAAGAAAAGCTGGCCACCCGGGGCGTTCAACCAGAAGA
AATCGACACCGTGCTAGAACTGGACGCCAAGCGGCGCGAACTCCTGCAACAAACCGAAACCCTGAAGGCCAAGCGTAACG
AAGCCTCCAAGAAGATCGGGGAAGCTAAGCGGGCCAAGCAATCCGCTGACGAAGCAATTGCCGAGATGCGCCAAGTCGGC
GAAGACATCAAGGCCTTAGACGAACAGGTGGAAGCAAACGACAAGGACCTCTTTGACAAGTTAGCCCACCTGCCGAACGT
CCCTCACGAAGGGGTGCCGGTTAGCCTGACCGAAGATGGGGCCGAAGAACTGCGTAAGGTAGGTCAAGCCCGTCAATTCG
ACTTTGAACCAAAGCACCACTGGGAAATCGGCGAAAACCTCGGGATTTTGGACTTTGAACGGGCCGGTAAGGTTTCTGGC
TCCCGCTTCGTCTACTACGTCGGCCTCGGGGCTCAATTAGAACGGGCGCTGTACAACTTCATGCTCGATGAACACATGAA
GGAAGGCTACACCGAAGTCTTGCCGCCGTACATCGTCAACGCTCACGCGATGTACGGGACCGGTCAATTCCCGAAGTTCA
AGCAGGACGTTTACCAAGTGAACGGCGAAGACATGACCCTGATCCCGACCGCCGAAGTTCCGTTGACCAACTACTTTGCC
GGCGAAGTGATCCCCGCAGAAAAGCTGCCGGTTTACGTGACGGCCTTGACGCCTAGCTTCCGTTCCGAAGCTGGGTCAGC
TGGTCGCGATACCCGCGGGTTGATCCGGATGCACCAATTCAACAAGGTCGAAATGGTTAAGTACACCAAGCAAGATCAAT
CCTGGGAAGAACTCGACAAGATGACGGCCAACGCCGAAAACATCCTCCAAAAGCTCGGCCTGCCGTACCACGTCATCACC
CTGACAACTTCGGACATGAGCTTCACGGCCTCCGAAACCCACGACCTGGAACTGTGGATGCCGGCCCAAAACAAGTACCG
GGAAGTTTCCTCTTGCTCCAACTGCTTGGACTTCCAAGCCCGGCGCCTGCACATGCAATACCGGGACGAAAACGGTAAGC
TCCAATACGTGCACACCCTGAACGGTTCTGGTTTAGCCGTTGGGCGGACGTTGGCGGCCATCTTAGAAAACTACCAAAAC
GAAGACGGCTCCGTGACGATTCCAGAAGTCTTGGTACCGTACTTCCACGGCATCACCAAGATCACCAAGGAAAACGCCGT
GCCGTTTAACAACAAGTAA

Protein sequence :
MLDIKQIRQQPDWFKEKLATRGVQPEEIDTVLELDAKRRELLQQTETLKAKRNEASKKIGEAKRAKQSADEAIAEMRQVG
EDIKALDEQVEANDKDLFDKLAHLPNVPHEGVPVSLTEDGAEELRKVGQARQFDFEPKHHWEIGENLGILDFERAGKVSG
SRFVYYVGLGAQLERALYNFMLDEHMKEGYTEVLPPYIVNAHAMYGTGQFPKFKQDVYQVNGEDMTLIPTAEVPLTNYFA
GEVIPAEKLPVYVTALTPSFRSEAGSAGRDTRGLIRMHQFNKVEMVKYTKQDQSWEELDKMTANAENILQKLGLPYHVIT
LTTSDMSFTASETHDLELWMPAQNKYREVSSCSNCLDFQARRLHMQYRDENGKLQYVHTLNGSGLAVGRTLAAILENYQN
EDGSVTIPEVLVPYFHGITKITKENAVPFNNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-129 62