Gene Information

Name : LAF_0021 (LAF_0021)
Accession : YP_001842837.1
Strain : Lactobacillus fermentum IFO 3956
Genome accession: NC_010610
Putative virulence/resistance : Unknown
Product : rRNA large subunit methyltransferase
Function : -
COG functional category : S : Function unknown
COG ID : COG1576
EC number : -
Position : 23681 - 24160 bp
Length : 480 bp
Strand : +
Note : SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA

DNA sequence :
ATGAACATTAAGATTATCGGGGTCGGCAAGGTCAAGGAAAAGTACTTTAAGGCCGGGATCGCCGAGTACGCCAAGCGGAT
GGAGCGCTACGCCAAGTTTGAAATTGTCGAGGTACCAGACGAAAAGGCCCCCGAGACCCTCAGTCAGGCCGAAATGGACG
CCGTGATGGCAAAGGAGGGTGAGCGGATCCTGGCGAAGATCAAGGACCGGGAATACGTTTATGCCCTGGCGATTAAGGGC
AAGGAACGTTCCTCAGAGGAGTTCGCTAAGGAAATCAACCAGCTGGCCACTTATGGCCACTCCGATATAACCTTTGTGAT
CGGCGGTTCCTTGGGGCTTAGTCCGGCCGTTTTAAAACGGGCCAACACCCAGATTTCCTTTGGGCGTTTTACTTTGCCCC
ATAAGTTGATGCGCTTGGTCTTAGCCGAGCAAATCTACCGGGCCTTCACGATCATTAATGGCCTGCCCTACCATAAGTAG

Protein sequence :
MNIKIIGVGKVKEKYFKAGIAEYAKRMERYAKFEIVEVPDEKAPETLSQAEMDAVMAKEGERILAKIKDREYVYALAIKG
KERSSEEFAKEINQLATYGHSDITFVIGGSLGLSPAVLKRANTQISFGRFTLPHKLMRLVLAEQIYRAFTIINGLPYHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAC57492.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 2e-36 57
SAR0024 YP_039501.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 4e-36 57
unnamed BAB72121.1 hypothetical protein Not tested Type-IVa SCCmec Protein 2e-36 57
SAV0024 NP_370548.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 4e-36 57
unnamed BAB72138.1 open reading frame X Not tested Type-IVb SCCmec Protein 2e-36 57
unnamed BAC67575.1 open reading frame X Not tested Type-IVc SCCmec Protein 2e-36 57
unnamed BAA82243.1 orfX Not tested Type-II SCCmec Protein 2e-36 57
unnamed BAD24821.1 conserved hypothetical protein orfX Not tested Type-V SCCmec Protein 2e-36 57
orfX BAA86653.1 open reading frame X Not tested Type-I SCCmec Protein 2e-36 57
unnamed BAG06184.1 conserved hypothetical protein orfX Not tested Type-VII SCCmec Protein 2e-36 57
unnamed BAB47681.1 open reading frame X Not tested Type-III SCCmec Protein 2e-36 57
unnamed BAC53844.1 open reading frame X Not tested SRImec-III and SCCmec-III region Protein 2e-36 57
orfXhom BAB83497.1 open reading frame X Not tested SCC 12263 Protein 7e-33 56
orfX AAL26648.1 unknown Not tested SCCcap1 Protein 3e-36 56
SE0023 NP_763578.1 rRNA large subunit methyltransferase Not tested SCCpbp4 Protein 1e-35 56
SERP2529 YP_190070.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 1e-35 56
orfX YP_251938.1 rRNA large subunit methyltransferase Not tested SCCmec Protein 3e-35 55
SSP0026 YP_300116.1 rRNA large subunit methyltransferase Not tested SCC15305RM Protein 4e-36 54
unnamed ACL99851.1 hypothetical protein Not tested Type-V SCCmec Protein 6e-23 52