Gene Information

Name : LAF_1526 (LAF_1526)
Accession : YP_001844342.1
Strain : Lactobacillus fermentum IFO 3956
Genome accession: NC_010610
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1722730 - 1725234 bp
Length : 2505 bp
Strand : -
Note : -

DNA sequence :
ATGGATAACGAAAATCTATACACACCAAGCGCCAATAACGTCTTGCGGATTGCCCAGGAACAGGCGCGCTTTTTTAAACA
CCAAGCCGTCGGGACGGAACACCTCCTCTTGGCCTTGAGCCTCGAAAAGGTGGGGGTGGCTGCGACGGTTTTGCACCAGT
TTAACGTCACTAGTGACGACCTGCGTGAAGAGATTGAACGCTACACCGGGTACGGAACCATGCAAAACACCGCTAGCGAT
GCGTACCTACCTAATTCGCCAAAGTTACGCGAAATTTTGGCCCTGGCAGCCCGCTTGGCCCAACAAATGGGGGCAAGACG
TGTGGGTACTGAGCACCTATTGTTGGCCCTGTTGTCAGATGAGACCATCCTTTCCTCGCGGATCCTTTTGAACTTGGACG
TGGAACCAAAGCAAGCCCGCCGGATGTTGTTACGGCGTTTGGGGGTTTCTCAAGAGGGACGGCGCAACCGCCGGCAAAAC
CAAGCCAATACCCAACCGGAGGAGGGGGAAGGGACTACGCCAACCCTCGATAAGTACGGCCGTGATTTGACAAAGGTGGC
CAGGGAAGAAGGGCTTGACCCCGTAATTGGACGGGAAAAAGAAATCAAGCGGGCGATTCAGATCCTCGCCCGGCGGGCCA
AGAATAACCCGGTCCTGTTAGGGGAACCGGGGGTCGGAAAGACGGCGATTGTCGAGGGCCTTGCCCAACGGATAGTTAAC
GGTGAAGTTCCTAATGAACTAGCCGAAAAGCGCTTGGTGGTCCTGGATATGGGGACCTTGGTTGCCGGTACCAAATTCAG
GGGTGAATTCGAGGGGCGGATCAAAAACGTCATCGATGAAGTTTACCGGGACGGCAAAATTATCTTATTTATTGACGAAA
TCCACACCATGATTGGTGCCGGGGGAGCAGAGGGGGCGATTGACGCCTCCAACATTCTCAAACCGGCCCTGGCCCGGGGG
GAACTCCAGTTGATTGGGGCGACTACCCTGGACGAGTACCAAAAGTACGTTGAAACCGATGCGGCCTTAGAACGGCGTTT
TGCGACGATCATGGTTGAAGAGCCAACTAAGGAGCAGACCCGCCAAATCCTCGAGGGAATTCGGCCCCGCTATGAAAAAC
ACCACCACGCCAAGATTACTGATGAAGCGCTGATGGCGGCGGTTAACTTGTCGAGTCGTTACATTACCAACCGTTTCTTA
CCGGATAAGGCGATTGACCTGATCGATGAGGCCGGGGCAATGGTCCGCATCGATGGTGAAGAAAAGGGGAACCAAAAGAA
TGGCTTGACGGTCAAGTTAGAGGAACTCCGGGCACAAAAAGAGGACGCAATTGCCGAGCAAGACTTTGACCGGGCGGCCG
ACTTACGCCACGAAGAGCTAACGGTTAAGCGACAAATCGAAGAACAGCGGGAACGAGACGCCCAGTTGGTTGCCGATGGC
AAGTTCCTGTACACCGTGACGGCTGAAGACATTGCCAAGGTAGTTAACGAATGGACCGGGGTGCCGTTAACCCAACTCCA
AAAGAAGGAAAGCGATCGCTTGGTTAACCTGGAGAGGGTGCTTCACAAACGAGTGATCGGCCAAGACGAAGCCGTTTCGG
CGATTGCCCGGGCAATTCGCCGGGCCCGCAGCGGCTTAAAGGACCCGAACCGGCCGATTGGTTCCTTCATGTTCTTAGGA
CCAACCGGGGTTGGGAAGACCGAGCTGGCTAAGGCGTTAGCCGAAGCGATGTTTGGCCAAGAAGACAACATGATCCGGAT
TGATATGTCCGAGTACATGGAACGCTATTCGACCAGCCGGTTAGTCGGGGCGGCGCCAGGTTACGTCGGCTACGACGAAG
GTGGACAGTTGACCGAACAGGTTCGCCAACACCCGTACTCCGTCGTCTTATTAGATGAGGTGGAAAAGGCCCACCCAGAT
GTCTTTAACCTCCTGTTACAGGTCTTAGATGATGGGGTTTTGACCGATTCCAAGGGACGTAAGGTTGACTTCCGGAACAC
GATTTTGATCATGACCTCCAACTTGGGGGCGACCCAGTTGGCCGATGAAAAGACGGTCGGCTTCGGGGCGACTGGCGTTC
AAAATAATTACCAAGCGATGTCGGCGGCCATCAGGCAACAGATGCGCTTGCACTTCCGGCCGGAGTTCTTGAACCGGATT
GATGAGACCGTGATCTTCCACTCGTTGACCAAGGAAAATATTCACCAAGTGGTTAAGCTCTTGAGCGCCCAGTTGGTAAA
GCGGGTGGCGGAACAAAAGATCAGCCTGAAACTGACCCCGGCTGCCATTGAGTTAGTAGCGGCGAAGGGGTACAACCCTG
AATACGGGGCGCGGCCATTACGGCGGGCCTTACAAACGATGGTGGAAGACCCGCTCTCCTTATCGATGATTGATGGCCAA
GTTGCGGCCGGTGATCAAGTGACGATTGGTGCCCAACGGGGGAAATTGAGCTTCAAAGTCAAAACTTCTGACAACGCTTC
CCGGAACCTAGTTCTCCAAAATTAA

Protein sequence :
MDNENLYTPSANNVLRIAQEQARFFKHQAVGTEHLLLALSLEKVGVAATVLHQFNVTSDDLREEIERYTGYGTMQNTASD
AYLPNSPKLREILALAARLAQQMGARRVGTEHLLLALLSDETILSSRILLNLDVEPKQARRMLLRRLGVSQEGRRNRRQN
QANTQPEEGEGTTPTLDKYGRDLTKVAREEGLDPVIGREKEIKRAIQILARRAKNNPVLLGEPGVGKTAIVEGLAQRIVN
GEVPNELAEKRLVVLDMGTLVAGTKFRGEFEGRIKNVIDEVYRDGKIILFIDEIHTMIGAGGAEGAIDASNILKPALARG
ELQLIGATTLDEYQKYVETDAALERRFATIMVEEPTKEQTRQILEGIRPRYEKHHHAKITDEALMAAVNLSSRYITNRFL
PDKAIDLIDEAGAMVRIDGEEKGNQKNGLTVKLEELRAQKEDAIAEQDFDRAADLRHEELTVKRQIEEQRERDAQLVADG
KFLYTVTAEDIAKVVNEWTGVPLTQLQKKESDRLVNLERVLHKRVIGQDEAVSAIARAIRRARSGLKDPNRPIGSFMFLG
PTGVGKTELAKALAEAMFGQEDNMIRIDMSEYMERYSTSRLVGAAPGYVGYDEGGQLTEQVRQHPYSVVLLDEVEKAHPD
VFNLLLQVLDDGVLTDSKGRKVDFRNTILIMTSNLGATQLADEKTVGFGATGVQNNYQAMSAAIRQQMRLHFRPEFLNRI
DETVIFHSLTKENIHQVVKLLSAQLVKRVAEQKISLKLTPAAIELVAAKGYNPEYGARPLRRALQTMVEDPLSLSMIDGQ
VAAGDQVTIGAQRGKLSFKVKTSDNASRNLVLQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-176 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAF_1526 YP_001844342.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 0.0 55
LAF_1526 YP_001844342.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 7e-143 50