Gene Information

Name : LAR_0091 (LAR_0091)
Accession : YP_001841087.1
Strain : Lactobacillus reuteri JCM 1112
Genome accession: NC_010609
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 121348 - 122655 bp
Length : 1308 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATTAAAAAGATTCGTCAAGAACCTGATTTTTATAAGGAAAAGTTAGCTACGCGTGGTGTAAAACCAGAAGA
AATTGATGAAGTTATTGCGTTAGATAAAAAGCGGCGGGAATTGCTCCAACAAACTGAAACAATGAAGGCGCAACGTAATG
AAGCATCAAAGAAGATTGGAGAAGCTAAGCGTAATGGTGAATCCGCCGATGCTGCCATTAAGGAAACTCGTGAACTTGGT
GATAAGATCAAGGAATTGGATACTGAAGTTGAAGCAAATGATGCTGAACTTCATGATAAGATGGCTCATCTTCCGAATGT
TCCACATGATGGTGTTCCAGTTAGCTTAACGGAAGACGGTGCCGTTGAATTACGGAAAGTCGGTAAGGTGCGGGACTTTG
ATTTTGAACCTAAGCATCACTGGGATATCGGTGAAAACCTTGGTATTTTAGACTTTGATCGCGCTGGTAAGGTTTCTGGT
GCGCGTTTTGTCTACTACTTAGGTCTTGGTGCTCAGCTTGAACGGGCAGTTTATAACTTCATGCTTGATGAACACATGAA
GGAAGGATATACCGAAGTCTTACCACCATATATCGTCAATGCTGATTCAATGTATGGTACTGGTCAATTCCCTAAGTTCA
AAGAAGGAGTTTACCAGGTTAACGGTGAGGATATGACATTGATCCCAACTGCTGAAGTTCCATTGACTAATTACTACCGT
GGCGAAGTTATCCCAACTGAAGAATTACCGGTTTATGTTACTGCTTTAACACCATCATTCCGTTCTGAAGCGGGAGCAGC
GGGTCGTGATACCCGAGGATTGATCCGGATGCACCAATTTAACAAGGTAGAAATGGTTAAGTACACTAAACCAGAGAACT
CATGGGATGAACTTGAAAAGATGACGGCTAACGCTGAAAACATCTTGAAGAAGTTAAACTTGCCATACCATGTTATTACC
TTAACTACTGGTGACATGAGCTTTACGGCATCTGAAACCCATGACCTTGAATTGTGGATGCCAGCACAAAATAAGTATCG
TGAAGTTTCGAGTTGTTCAAACTGCTTGGACTTCCAGGCACGGCGGATGCACACACAATACCGGGATGAAAATGGTAAGT
TACAATATGTTCACACACTTAACGGTTCTGGTTTAGCCGTTGGTCGGACAGTTGCAGCTATCTTGGAAAACTATCAAAAC
GCTGATGGTTCTGTAACAATTCCAGAAGTATTGGTACCATACATGCATGGTGTTACTAAGATTACTAAGGAAAATGCGGT
TCCTTTCCGTAATAAAGTTAATAAATAA

Protein sequence :
MLDIKKIRQEPDFYKEKLATRGVKPEEIDEVIALDKKRRELLQQTETMKAQRNEASKKIGEAKRNGESADAAIKETRELG
DKIKELDTEVEANDAELHDKMAHLPNVPHDGVPVSLTEDGAVELRKVGKVRDFDFEPKHHWDIGENLGILDFDRAGKVSG
ARFVYYLGLGAQLERAVYNFMLDEHMKEGYTEVLPPYIVNADSMYGTGQFPKFKEGVYQVNGEDMTLIPTAEVPLTNYYR
GEVIPTEELPVYVTALTPSFRSEAGAAGRDTRGLIRMHQFNKVEMVKYTKPENSWDELEKMTANAENILKKLNLPYHVIT
LTTGDMSFTASETHDLELWMPAQNKYREVSSCSNCLDFQARRMHTQYRDENGKLQYVHTLNGSGLAVGRTVAAILENYQN
ADGSVTIPEVLVPYMHGVTKITKENAVPFRNKVNK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-133 64