Gene Information

Name : LAR_0819 (LAR_0819)
Accession : YP_001841815.1
Strain : Lactobacillus reuteri JCM 1112
Genome accession: NC_010609
Putative virulence/resistance : Unknown
Product : type I restriction-modification system restriction subnit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 933668 - 936793 bp
Length : 3126 bp
Strand : +
Note : -

DNA sequence :
GTGGCAAGTTATCTTAACGAAGAAAATATAGAGGGCATTGCTTTAAGATGTCTTGATGAAGTAGGCTATCAAGTCTACAA
AAGTGCTAGTTATACTAGTCCGAATGTAGAAATAGATGCTGAAAGAAATAATGACCATACACAACCTATTTTAAAAGGAC
AATTAGAAAACGCTTTACGCAAGTTAAATTCTGGACTTGATGATGAAGTATACCGTAATGCCATTCATCAATTTGAAATG
CTAGCAGATAGCCCAGATATGATGCTTAATAACCATAAACTTCATGAATTAATTATCGGCGGAGCAAAAGTAAAAACATC
AATTAAAGGTGAGGACCGGACCATTACTTTGTATCCGATTGATTTTAAAAACGTTGATAACAATACATTTATTGCAACAA
ATCAATTTACAATGAAACAAGGAGAACATGAAAGAAGACCAGACATTACTCTTTTTATTAATGGGCTTCCTTTAGTTACC
TTTGAATTAAAGAACCCAGCAAATGCGAATGTAGGTATTCAACAAGCTTTTGCCCAATTTTCTACTTATAAAGAAGAAAT
ATCTTCTTATATGCAATATAACGAAATTTTAATTGTTTCTGATGGAATTAATGCGCGAGCTGGGTCATTAACAGCGGGAA
TTGATCGCTTTATGCGGTGGCGCGAGCCGAAAAATGTAGATATTGACGATTCAATGATGGAATTAGAAGTATTGATAAAA
TACATGCTTACCCCATCTGATTTATTAAACATCATTCAGAATTTTATTCTTTTTGAAAGTGATGGAGACAAGACAATCAA
GATTTTAGCAGCATATCATCAATACTATATGGTTAATAAAGCTGTAAAAAGAACATCAAAAGTATTGGCTGACCCTGATG
ACAAACGAATTGGTGTTGTTTGGCATACCACTGGTTCTGGTAAATCATTGTCGATGGTCTTTTATTCTGGAATAGTAGCT
CGTAAACTTGGTAATCCAACTATTTTAGTAATTAATGATCGTAATGATTTAGATGATCAGTTATTTGGTACTTTTGCGGC
TGCTCATGAATATCTACAACAAAACCCTGATCACGCTGAATCACGAGGAGAAGTTCGTAAATACATGAGTAAGAATTCTG
GCGGGATTGTTTTTAGTACAATTCAAAAATTCTCACCAAACTTTGACGCAGGTGAAGAACATATGCCTATACTTACAAAC
CGTTCTAACGTTATCGTAATGGTTGATGAAGCTCATCGGTCTCAATATGGAATGCAAGCAAAACTAACCGATAATGGTAT
TCGTTATGGATATGCTAAATATTTGCGTGAGGCTCTTCCTAACGCCTCGTTTATTGGTTTTACAGGAACACCAATAAATA
CTGAAGATAAATCTACCGTGGCAATGTTTGGAAATTACATTGATGTTTATGATATTACTCAAGCAGTTAATGATCATGCC
ACGGTCCGGATTTATTATGAAAGTCACGTTTTCCCATTAAAGCTTAAGGACAATGCAATTGATGAATATCAAAAGTTAAT
TAAAGAAGCTGGTATTAATGACGATCCTAATCTTAGAGAAACTGAGCGACGGAATCGGGCATTTACTAGATTAGAGGCCC
TTGCCGGTGCAAAACCACGGTTAGAAAAAATAGCCCAACACTTTGTTCATCATTTTGAATCACGACAAAAGGAAGAATTT
GGTAAGTCGATGATTGTTGAAATGTCACGACAAAATGCAGTAAAGCTATATAATGAAATTGCAAAATTACGTCCTGAGTG
GATAAATGATGATATTCATAAGGGAAAAATCAAAGTTATTATGACGTCTAATGCTTCTGATGGCCCAGAATTTGCTAAAT
TTAAGACAAGCAAACAAGACCGATTTACGTTACAACAACGGATGAAAGATAACGATGACGAATTACAAATTGTAATAGTT
GTTGATATGTGGCTAACTGGATTTGATGTTCCTAGCATGAATACCATGTACATTGACAAGCCAATGCAAGGACATAATCT
TATCCAGGCAATTGCTCGTGTTAATCGAGTATTTAAGAATAAAGATAGTGGGTTAATTGTCGATTACATTGGGATTGCTG
ATGCTCTTCGTTTTGCCTTAAATGTATACACAAAAGATGACCAAGGAAAAGTTGGAATTAATGTTGATCGTGCACTAATG
CTTCTAAAAGAGAAATATGACATTATTAAAGAAGATTTCCTATATGGGATTGATTACTCAGAATTTGATTCTGATGATAG
CCAAACTCGTCAGAAGGCAGTTACTCGTGTTGTAAATGAATTAGCTGCAGAGGACGATGAAACAAAACAAAAATTCTTTG
ATGTAGTAACAGAACTTCAAAAAGCTTATGCATTAGTTTCAACACAGCCGGAAGCCCAAGATTTAAGTGCGGAGATAGCA
TTCTTTAAAACGGTTAAAGTATTCTTAACTAAGCTTGAGGCTCCTGACGATCCAGATGATAGTAAAGAGATTCATAGTTC
TGTTGATTATCGAATGCAACAACTATTAGATCAATCAATTATTTCAGAGCCGAACGTTGACATTTATCGTGACCTAGGAT
TAGAACGCCCTAACTTAGATTTAATCTCAGAACAATTTCTTGAAAAAGTAAATGAAATTACTGAGAAAGATCTAGCAATT
ACTCTTTTAGAGAAACTATTAAAAGGGCAAGTAAAAGCCTACCAAAAAACGAATATTGTTAAAGGCAAGAAGTTTGAGGA
ATTACTTCAAGAGTCAATTGATGATTACAATAGGCGGGGAATTACCAGTGAAATTGTAATTAGAAAGTTAATTGATATGG
CTAAGGAAATTAATAAAGAACAACAAGAAGGTAAGAATCTGGGACTTTCAAAAGAAGAAGTTGCCTTTTATGATGCTTTA
GCTGATCATGAGAAAGCTGTTCAAGAATTAGGAGAAGAAAAGTTACATCTTATTGCTGCTGAATTAGTAAAGACTGTAAA
GCAACAATCAGGGGTTGATTGGGAGCGGCGCAGCAATGTTCGTGCTAAAATGCGTGTTGCAGTTAAACATCTATTACGTA
AGTATGGTTATCCACCTGATATTGCTCCAGATGCCATTAAGACCGTAGTAAAGCAAGCTGAACAAATGGCTTCTCAAGAG
AGCTAA

Protein sequence :
MASYLNEENIEGIALRCLDEVGYQVYKSASYTSPNVEIDAERNNDHTQPILKGQLENALRKLNSGLDDEVYRNAIHQFEM
LADSPDMMLNNHKLHELIIGGAKVKTSIKGEDRTITLYPIDFKNVDNNTFIATNQFTMKQGEHERRPDITLFINGLPLVT
FELKNPANANVGIQQAFAQFSTYKEEISSYMQYNEILIVSDGINARAGSLTAGIDRFMRWREPKNVDIDDSMMELEVLIK
YMLTPSDLLNIIQNFILFESDGDKTIKILAAYHQYYMVNKAVKRTSKVLADPDDKRIGVVWHTTGSGKSLSMVFYSGIVA
RKLGNPTILVINDRNDLDDQLFGTFAAAHEYLQQNPDHAESRGEVRKYMSKNSGGIVFSTIQKFSPNFDAGEEHMPILTN
RSNVIVMVDEAHRSQYGMQAKLTDNGIRYGYAKYLREALPNASFIGFTGTPINTEDKSTVAMFGNYIDVYDITQAVNDHA
TVRIYYESHVFPLKLKDNAIDEYQKLIKEAGINDDPNLRETERRNRAFTRLEALAGAKPRLEKIAQHFVHHFESRQKEEF
GKSMIVEMSRQNAVKLYNEIAKLRPEWINDDIHKGKIKVIMTSNASDGPEFAKFKTSKQDRFTLQQRMKDNDDELQIVIV
VDMWLTGFDVPSMNTMYIDKPMQGHNLIQAIARVNRVFKNKDSGLIVDYIGIADALRFALNVYTKDDQGKVGINVDRALM
LLKEKYDIIKEDFLYGIDYSEFDSDDSQTRQKAVTRVVNELAAEDDETKQKFFDVVTELQKAYALVSTQPEAQDLSAEIA
FFKTVKVFLTKLEAPDDPDDSKEIHSSVDYRMQQLLDQSIISEPNVDIYRDLGLERPNLDLISEQFLEKVNEITEKDLAI
TLLEKLLKGQVKAYQKTNIVKGKKFEELLQESIDDYNRRGITSEIVIRKLIDMAKEINKEQQEGKNLGLSKEEVAFYDAL
ADHEKAVQELGEEKLHLIAAELVKTVKQQSGVDWERRSNVRAKMRVAVKHLLRKYGYPPDIAPDAIKTVVKQAEQMASQE
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 49
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 49
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 49
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 43