Gene Information

Name : LAR_0043 (LAR_0043)
Accession : YP_001841039.1
Strain : Lactobacillus reuteri JCM 1112
Genome accession: NC_010609
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 47316 - 49553 bp
Length : 2238 bp
Strand : +
Note : -

DNA sequence :
ATGGCTCAAAACCCAATGAATCCATTTGACAACGACATGAATGACATCTTTAATCAATTAATGGGTGGCATGAATGGTTT
CAATTCTGATAATCGGCGTTACCTAATCAATGGTCGTGAAGTAACACCAGAAGAATTTGCTGAATATCGTAGAACTGGTC
AATTGCCAGGCGGTGCAAATCCTCAACAAGGTGGGCAACCTGGCCCTCAACCTAACGCAGGTAAGGACAGTATCTTACAC
AAGTTAGGTCGAAACTTAACTCAAGAAGCTCGTGAACATGAACTTGACCCTGTTATTGGTCGGAACAAGGAAATCCAAGA
AACAGCTGAAATTTTAAGCCGGCGGACAAAGAACAACCCTGTATTAGTTGGGGATGCTGGTGTTGGTAAGACTGCTGTTG
TTGAAGGTTTAGCACAAGCAATTGTTTCCGGCGATGTACCAGCTGCTATCAAGGACAAGGAAATTATCAGTATCGATATT
TCTGGCCTTGAAGCAGGTACTCAATATCGTGGTAGTTTTGAAGAAAACATGCAAAAGTTGGTTGATGAAGTCAAGAAGGC
TGGAAATATCATCCTCTTCTTCGATGAAATTCACCAAATTATTGGTGCCGGTTCAACTGGTGATTCTAGTGGTTCCAAGG
GTATGTCTGACATTATTAAGCCAGCATTATCCCGTGGTGAACTAACAGTTATCGGTGCAACTACTCAAGATGAATACCGG
AACACTATTATGAAGGATGCTGCATTAGCACGGCGGTTCAATTCTGTTACTGTTAATGCTCCAAGCAAGGCTGATACAGT
GGCCATCCTTAAAGGTATCCGTGACTTGTACGAACGTCACCACAATGTAAAGTTACCAGATGACGTTCTCCAAGCTGCTG
TTGATTACTCTGTTCAATACATGCCACAACGCGCATTACCTGACAAGGCTATCGACTTAATCGATATGACCGCTGCTCAC
TTAGCAGCAAAGCACCCAGCACGTGATGCTAAGGCAATTGAAAAAGATATCGAAGCAGAAGAAAAGAAGCAAAAAGCGGC
TGCTAAGAAAGAAGATTACAAGGCTGCCCAAGATGCCAAGGAAAAGATTGCTGACTTGAAGAAGCAATTGAGTGAAAACT
CTGAATCTGAAAAGGTTACTGCTACTCCAGAAGACGTTGCTAAGGCTGTAGAACAAATGACTGGTATTCCTGTTTCTAAG
ATTGGTGCTAGTGACGTTGAACGCTTAAAGGACATGGACAAGCGGCTTGAAGGTAAGGTTATTGGCCAAGACAAAGCTGT
TGAAGCAGTTGCTCGTGCTATTCGTCGTAACCGTGCTGGATTTGACGAAGGCGATTCACCAATTGGTAGTTTCCTCTTCG
TTGGACCTACTGGTGTTGGTAAGACTGAACTTGCTAAGCAACTAGCCCTTGATATGTTTGGTAGCAAGGATGACATTATT
CGGTTAGATATGTCTGAATACTCTGACCGGACAGCCGTATCTAAGATGATCGGTGCTACTGCTGGTTATGTTGGTTACGA
AGACAACGGTAATACCTTGACTGAAAAGGTTCGTCGTCACCCTTATTCAATTATTCTTCTTGATGAAATTGAAAAGGCTA
ATCCACAAGTTATCACCCTCTTGCTTCAAGTACTTGATGATGGTCGGTTAACTGATGGACAAGGTAACACTATTGACTTT
AAGAATACTGTTATCATTGCTACATCAAATGCCGGCTACTCCAACGATGCTCCAGTTAAGATGGGCCGGAACGAAGATGA
AGAAGACTTAATTAAGAAGTTGACTACTTACTTCCGTCCTGAATTCTTGAACCGGTTCAACGCTATTGTTGAATTCCACA
GCTTGACTAAGGAAGACTTGAAGCAAATCGTTGACTTAATGCTTGCTGAAGTTAACCGGACATTGGCTAAGAAGGGCATG
GATGTTAAGGTTACTGATACTGCAAAGCAATACCTTATTGATGAAGGTTACGATGAAGCCATGGGTGCTCGTCCTCTTCG
TCGGGTTATCGAACGTGAAATCCGTGATAAGGTAACTGATTACTACCTTGACCACCTCGATGCAAAGAATCTTGTTGCTG
AAATGAAGGATGGCCAACTTGTAATTGTTGACGCTAAGGACGCCTCAAAAGACGATAGTAAAGAATATACTTCACCATCT
GAAAAGAAGGATGAAGAAAAAGACGATAAGAAGGAAGAAGACAAGAAGTCTGACGAAGATAAGAAAGACGAAAAGTAA

Protein sequence :
MAQNPMNPFDNDMNDIFNQLMGGMNGFNSDNRRYLINGREVTPEEFAEYRRTGQLPGGANPQQGGQPGPQPNAGKDSILH
KLGRNLTQEAREHELDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVSGDVPAAIKDKEIISIDI
SGLEAGTQYRGSFEENMQKLVDEVKKAGNIILFFDEIHQIIGAGSTGDSSGSKGMSDIIKPALSRGELTVIGATTQDEYR
NTIMKDAALARRFNSVTVNAPSKADTVAILKGIRDLYERHHNVKLPDDVLQAAVDYSVQYMPQRALPDKAIDLIDMTAAH
LAAKHPARDAKAIEKDIEAEEKKQKAAAKKEDYKAAQDAKEKIADLKKQLSENSESEKVTATPEDVAKAVEQMTGIPVSK
IGASDVERLKDMDKRLEGKVIGQDKAVEAVARAIRRNRAGFDEGDSPIGSFLFVGPTGVGKTELAKQLALDMFGSKDDII
RLDMSEYSDRTAVSKMIGATAGYVGYEDNGNTLTEKVRRHPYSIILLDEIEKANPQVITLLLQVLDDGRLTDGQGNTIDF
KNTVIIATSNAGYSNDAPVKMGRNEDEEDLIKKLTTYFRPEFLNRFNAIVEFHSLTKEDLKQIVDLMLAEVNRTLAKKGM
DVKVTDTAKQYLIDEGYDEAMGARPLRRVIEREIRDKVTDYYLDHLDAKNLVAEMKDGQLVIVDAKDASKDDSKEYTSPS
EKKDEEKDDKKEEDKKSDEDKKDEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 3e-125 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAR_0043 YP_001841039.1 ATP-dependent Clp protease ATP-binding subunit VFG0080 Protein 4e-140 49
LAR_0043 YP_001841039.1 ATP-dependent Clp protease ATP-binding subunit VFG0079 Protein 6e-133 48