Gene Information

Name : LAR_1257 (LAR_1257)
Accession : YP_001842253.1
Strain : Lactobacillus reuteri JCM 1112
Genome accession: NC_010609
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpE
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1421208 - 1423412 bp
Length : 2205 bp
Strand : +
Note : -

DNA sequence :
ATGCAATGTCAATACTGTCATCAAAATCCAGCCACAATTCATCTTCAAATGAATTTTAATGGGCAACGGATTCAAATAGA
CCTCTGCCAAAATTGTTATCAAAAATTACAAAATCTACAAACAGATATGATGAATGGAGGTAACGGAATGAATAATTTCG
GTTTTGGAAGCCTCGAAGACTTCATGAACGCAATGAACAATATGCAAAGTCAAGCTGCCGGTACTAATGGTCAAAACATG
AACGGCCAATCCCAACGACAAGGTGGCGGACGAAATGGAAAAGGAATCCTTGGTCAATATGGGATCAACCTTACTGATCT
CGCTCGCCAAGGTAAAATTGACCCAGTCATCGGGCGCGACAATGAAATTAAACGAGTTATTGAAATTTTAAACCGTCGAA
CCAAGAATAACCCAGTCTTGATTGGTGAAGCTGGAGTTGGTAAGACCGCGGTTGTTGAAGGTTTAGCTCAAGCAATCGTT
AGCGGCCAAGTTCCCGAAAAGCTTGCTAACAAGGAAATCATCCGGCTCGATGTTGTTTCCTTAGTTCAAGGTACGGGAAT
TCGGGGCCAATTTGAAAAGCGGATGCAACAATTAATGGAAGAAGTTCGTAAGAATAAGAACATCATCCTCTTTATTGACG
AAATCCATGAAATCATGGGTGCGGGAAATGCTGAAGGCGGAATGGACGCTGGAAATGTTCTTAAACCCGCCCTTGCCCGC
GGTGACTTCCAATTAGTTGGTGCCACTACTCTTAATGAGTACCGGAAGATCGAAAAGGATGCTGCTCTTGCACGGCGATT
CCAACCAGTTGAAGTTGATGAACCATCCGTTGAAGAAACAATCCGCATCTTAAACGGGATCAAAAGTCGTTATCAAGATT
ACCACCACGTTAAGTACACAGATGACGCAATTGTAGCAGCTGCTAAACTTTCTGACCGCTACATTCAAGATCGTTACTTG
CCTGACAAAGCTATCGACTTACTTGATGAAGCGGGATCAAAGAAGAACTTAACGCTTAAAAATGTGGATCCAAATGCAAT
CGAAAATGAAATCCACACAGCTGAAGCACACAAGCAACAAGCAGCTGATAACCAAGACTATGAAAAGGCAGCTTTCTACC
GCGATCAAGTTGCTAAGCTTGAAAAGGCAAAGAAGGAAGCCGAAGAAAACCATACTGAAGATTCTGCAACTGTTACCGTT
AAGGATATGCAGAGAATCGTTGAAGAACGGACAAATATTCCAGTTGGTGACCTGCAAAAGCAAGAAGAAAATCAACTTCG
CGACCTTGATAAGAAGCTTGATGAACATGTTATTGGCCAAGCCCAAGCAGTGGATAAGGTTGCTCGTGCCATTCGTCGTA
ACCGGATCGGTTTGAACAAGTCTGGTCGGCCAATTGGTAGTTTCCTCTTTGTTGGTCCTACGGGGGTTGGTAAGACTGAA
ACCGCTAAGCAACTTGCCCTCCAATTGTTTGGTTCTAAAGATGCTATGATTCGGTTCGATATGTCTGAATACATGGACAA
GACCTCTACTTCTAAATTAATCGGGGCTGCTCCTGGTTATGTTGGTTACGAAGAAGCTGGTCAGTTGACTGAACAAGTAC
GGCGGCACCCTTATAGCTTGATCTTACTTGATGAAGTTGAAAAGGCGCACCCAGATGTTATGCACATGTTCTTACAAATT
CTGGATGATGGTCGTTTAACTGATTCTCAAGGGCGCACTGTTAGCTTCAAGGATACAATCATTATCATGACATCTAATGC
CGGAACTGGTGATTCAGAAGCAAGCGTTGGTTTTGGTGCTGAGTCTAATGGTAGTACTCATTCCATCATTGACAAGTTGA
CAAACTACTTCAAGCCAGAATTCTTAAACCGGTTTGATGACATTGTTCAATTCAATGCCCTCTCCAAGGATGACTTGATG
AAGATCGTTAACTTAATGATTGATGATGTTAATAACATGCTTGCTGATAAGAACTTGCATATCGAAGTCATTAACAATGT
TGAAGAAAAATTAGTTGACATGGGATTTGATCCAAAGATGGGTGCTCGTCCTCTTCGTCGGGTAATCCAAGAACAAATCG
AAGACCGGATTGCTGATTACGTTCTTGATCACAGTGACGCTCATAAATTAGTTGCTAAACTTGATGATAATGGTGACATT
GTTGTCGAAGAAACTGAAGAAGTACCAACAATTGCTAAAAAATAA

Protein sequence :
MQCQYCHQNPATIHLQMNFNGQRIQIDLCQNCYQKLQNLQTDMMNGGNGMNNFGFGSLEDFMNAMNNMQSQAAGTNGQNM
NGQSQRQGGGRNGKGILGQYGINLTDLARQGKIDPVIGRDNEIKRVIEILNRRTKNNPVLIGEAGVGKTAVVEGLAQAIV
SGQVPEKLANKEIIRLDVVSLVQGTGIRGQFEKRMQQLMEEVRKNKNIILFIDEIHEIMGAGNAEGGMDAGNVLKPALAR
GDFQLVGATTLNEYRKIEKDAALARRFQPVEVDEPSVEETIRILNGIKSRYQDYHHVKYTDDAIVAAAKLSDRYIQDRYL
PDKAIDLLDEAGSKKNLTLKNVDPNAIENEIHTAEAHKQQAADNQDYEKAAFYRDQVAKLEKAKKEAEENHTEDSATVTV
KDMQRIVEERTNIPVGDLQKQEENQLRDLDKKLDEHVIGQAQAVDKVARAIRRNRIGLNKSGRPIGSFLFVGPTGVGKTE
TAKQLALQLFGSKDAMIRFDMSEYMDKTSTSKLIGAAPGYVGYEEAGQLTEQVRRHPYSLILLDEVEKAHPDVMHMFLQI
LDDGRLTDSQGRTVSFKDTIIIMTSNAGTGDSEASVGFGAESNGSTHSIIDKLTNYFKPEFLNRFDDIVQFNALSKDDLM
KIVNLMIDDVNNMLADKNLHIEVINNVEEKLVDMGFDPKMGARPLRRVIQEQIEDRIADYVLDHSDAHKLVAKLDDNGDI
VVEETEEVPTIAKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-150 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LAR_1257 YP_001842253.1 ATP-dependent Clp protease ATP-binding subunit ClpE VFG0080 Protein 0.0 58
LAR_1257 YP_001842253.1 ATP-dependent Clp protease ATP-binding subunit ClpE VFG0079 Protein 6e-157 53