Gene Information

Name : ACICU_p0019 (ACICU_p0019)
Accession : YP_001840873.1
Strain :
Genome accession: NC_010605
Putative virulence/resistance : Resistance
Product : carbapenem-hydrolyzing oxacillinase
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG2602
EC number : -
Position : 13384 - 14226 bp
Length : 843 bp
Strand : +
Note : Beta-lactamase class D

DNA sequence :
ATGAAATTATTAAAAATATTGAGTTTAGTTTGCTTAAGCATAAGTATTGGGGCTTGTGCTGAGCATAGTATGAGTCGAGC
AAAAACAAGTACAATTCCACAAGTGAATAACTCAATCATCGATCAGAATGTTCAAGCGCTTTTTAATGAAATCTCAGCTG
ATGCTGTGTTTGTCACATATGATGGTCAAAATATTAAAAAATATGGCACGCATTTAGACCGAGCAAAAACAGCTTATATT
CCTGCATCTACATTTAAAATTGCCAATGCACTAATTGGTTTAGAAAATCATAAAGCAACATCTACAGAAATATTTAAGTG
GGATGGAAAGCCACGTTTTTTTAAAGCATGGGACAAAGATTTTACTTTGGGCGAAGCCATGCAAGCATCTACAGTGCCTG
TATATCAAGAATTGGCACGTCGTATTGGTCCAAGCTTAATGCAAAGTGAATTGCAACGTATTGGTTATGGCAATATGCAA
ATAGGCACGGAAGTTGATCAATTTTGGTTGAAAGGGCCTTTGACAATTACACCTATACAAGAAGTAAAGTTTGTGTATGA
TTTAGCCCAAGGGCAATTGCCTTTTAAACCTGAAGTTCAGCAACAAGTGAAAGAGATGTTGTATGTAGAGCGCAGAGGGG
AGAATCGTCTATATGCTAAAAGTGGCTGGGGAATGGCTGTAGACCCGCAAGTGGGTTGGTATGTGGGTTTTGTTGAAAAG
GCAGATGGGCAAGTGGTGGCATTTGCTTTAAATATGCAAATGAAAGCTGGTGATGATATTGCTCTACGTAAACAATTGTC
TTTAGATGTGCTAGATAAGTTGGGTGTTTTTCATTATTTATAA

Protein sequence :
MKLLKILSLVCLSISIGACAEHSMSRAKTSTIPQVNNSIIDQNVQALFNEISADAVFVTYDGQNIKKYGTHLDRAKTAYI
PASTFKIANALIGLENHKATSTEIFKWDGKPRFFKAWDKDFTLGEAMQASTVPVYQELARRIGPSLMQSELQRIGYGNMQ
IGTEVDQFWLKGPLTITPIQEVKFVYDLAQGQLPFKPEVQQQVKEMLYVERRGENRLYAKSGWGMAVDPQVGWYVGFVEK
ADGQVVAFALNMQMKAGDDIALRKQLSLDVLDKLGVFHYL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
oxa-23 AFV47968.1 class D beta-lactamase OXA-23 Not tested AbaR25 Protein 2e-65 51
oxa-23 AFV47996.1 class D beta-lactamase OXA-23 Not tested delta-AbaR25 Protein 2e-65 51
BJAB0715_00989 YP_008216137.1 Beta-lactamase class D Not tested AbaR27 Protein 2e-65 51
oxa23 AEO37447.1 class D beta-lactamase OXA-23 Not tested AbaR4 Protein 2e-65 51
bla(Oxa-23) AFH57213.1 carbapenemase Not tested AbaR4b Protein 2e-65 51
oxa23 AEZ06035.1 OXA-23 class D beta-lactamase Not tested Tn6167 Protein 8e-65 50
oxa-Ab ACV89830.1 carbapenem-hydrolyzing oxacillinase OXA-69 Not tested AbaR6 Protein 3e-71 49
oxa-Ab ACV89832.1 carbapenem-hydrolyzing oxacillinase OXA-69 Not tested AbaR7 Protein 3e-71 49
oxa-Ab ADK35783.1 carbapenem-hydrolyzing oxacillinase OXA-69 Not tested AbaR8 Protein 3e-71 49
blaOXA-129 AET25386.1 OXA-129 beta-lactamase Not tested PAGI-2(C) Protein 7e-36 42
bla OXA-129 AFG30109.1 OXA-129 beta-lactamase Not tested PAGI-2 Protein 7e-36 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY665723.gene.p01 Protein 4e-131 100
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase NC_010481.6155789.p0 Protein 4e-131 100
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase GU831575.1.gene1.p01 Protein 2e-130 99
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF102240.1.gene13.p0 Protein 6e-131 99
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ519090.1.gene1.p01 Protein 1e-130 99
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ122933.1.gene1.p01 Protein 3e-72 54
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU220744.1.gene1.p01 Protein 1e-68 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF650037.1.gene1.p01 Protein 2e-71 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM488989.1.gene1.p1 Protein 1e-65 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase NC_011586.7044972.p0 Protein 1e-65 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM488986.1.gene1.p1 Protein 1e-65 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM488992.1.gene1.p1 Protein 3e-65 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM488991.1.gene1.p1 Protein 3e-66 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AF201828.gene.p01 Protein 1e-65 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY795964.gene.p01 Protein 1e-65 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM488990.1.gene1.p1 Protein 1e-65 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM488988.1.gene1.p1 Protein 8e-66 51
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU220745.1.gene1.p01 Protein 6e-68 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ998857.1.gene1.p01 Protein 4e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ734811.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU375515.1.gene1.p1 Protein 3e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ425495.1.gene1.p01 Protein 6e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF581285.1.gene1.p01 Protein 1e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AM279652.1.gene1.p01 Protein 4e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ385606.gene.p01 Protein 2e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ425492.1.gene1.p01 Protein 5e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ888718.1.gene1.p01 Protein 7e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF653400.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase FJ872530.1.gene1.p01 Protein 3e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM570036.1.gene1.p01 Protein 9e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU547447.1.gene1.p1 Protein 2e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY750908.1.gene1.p01 Protein 1e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ309277.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY750907.1.gene1.p01 Protein 6e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF650034.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU019536.1.gene1.p01 Protein 3e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM113563.1.gene1.p01 Protein 8e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY750909.1.gene1.p01 Protein 1e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ734813.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ519088.1.gene1.p01 Protein 5e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase JN215211.1.gene1.p01 Protein 5e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ519089.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF650032.1.gene1.p01 Protein 3e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AM231719.1.gene1.p01 Protein 1e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM570035.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU019535.1.gene1.p01 Protein 2e-70 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ392963.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ519086.1.gene2.p01 Protein 3e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF650035.1.gene1.p01 Protein 5e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY750913.1.gene1.p01 Protein 7e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AJ309734.2.gene1.p01 Protein 2e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase GQ853679.1.gene1.p1 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ309276.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU547446.1.gene1.p1 Protein 5e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU019534.1.gene1.p01 Protein 7e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM113559.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM113558.1.gene1.p01 Protein 1e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY750910.1.gene1.p01 Protein 1e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase GQ853680.1.gene1.p1 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ491200.1.gene1.p01 Protein 5e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU547445.1.gene1.p1 Protein 6e-72 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase JN248564.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM113561.1.gene1.p01 Protein 3e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM113560.1.gene1.p01 Protein 1e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY750912.1.gene1.p01 Protein 2e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AB634250.1.gene1.p01 Protein 4e-71 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase FJ194494.1.gene1.p01 Protein 2e-64 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY288523.1.gene1.p01 Protein 1e-64 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY762325.1.gene1.p01 Protein 2e-65 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase JN638887.1.gene1.p01 Protein 4e-65 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM488987.1.gene1.p1 Protein 3e-65 50
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase NC_012813.7996741.p0 Protein 3e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY750911.1.gene1.p01 Protein 2e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ734812.1.gene1.p01 Protein 1e-70 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AM991978.1.gene1.p01 Protein 1e-67 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF650038.1.gene1.p01 Protein 2e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase NC_013506.8571544.p0 Protein 3e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF650033.1.gene1.p01 Protein 5e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ425494.1.gene1.p01 Protein 5e-70 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AF201827.1.gene1.p01 Protein 4e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM113564.1.gene1.p01 Protein 4e-70 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ519087.1.gene1.p01 Protein 6e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AJ239129.2.gene1.p01 Protein 3e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase DQ335566.1.gene1.p01 Protein 4e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase NC_013277.8458023.p0 Protein 3e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase NC_011595.7059224.p0 Protein 2e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF650036.1.gene1.p01 Protein 3e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase GQ853681.1.gene1.p1 Protein 1e-70 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AF201826.1.gene1.p01 Protein 8e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY862132.1.gene1.p01 Protein 3e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase JN603240.1.gene1.p1 Protein 8e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EF534256.2.gene1.p01 Protein 4e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HQ425493.1.gene1.p01 Protein 4e-70 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase HM113562.1.gene1.p01 Protein 7e-71 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AF509241.1.gene1.p01 Protein 3e-68 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase EU029998.1.gene2.p01 Protein 4e-70 49
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AY306130.1.gene1.p01 Protein 1e-45 42
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase AM932669.1.gene2.p01 Protein 4e-36 42
ACICU_p0019 YP_001840873.1 carbapenem-hydrolyzing oxacillinase X58272.1.gene1.p01 Protein 7e-35 41