Gene Information

Name : merB (MMAR_p10)
Accession : YP_001840837.1
Strain :
Genome accession: NC_010604
Putative virulence/resistance : Resistance
Product : alkylmercury lyase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 11654 - 12310 bp
Length : 657 bp
Strand : -
Note : cleaves the carbon-mercury bond of organomercuric compounds

DNA sequence : 
ATGAACCCCGACATCGCCCAACTCGCCCACCGGCTCAACGACTCACTCGGCGGCGACAACCCCGGCTCGACGCCCTGGAT
GTTGCGCCCGCTGCTCGACCTCCTCGCCCACGGAGCGCCGGTCACCATCGACCAACTCGCTGACGCCACCGCCACCACCG
TCGAGCAGGTGCGCCACGCCTTGACCGCCATGTCCGACACCGAATACGACGAACACGGCCGCATCATCGGCAGCGGCCTC
ACACTGCGCCCCACCCCGCACCGCTTCGACATCGACGGACGGCAGCTCTACACCTGGTGCGCGCTGGACACGCTCATCTT
CCCCGGCATCCTCGGCCGAACCGCCCACGTCACCTCGCCATGTCACAGCACTGGGCAACCCGTGCACCTCACCATCGACA
CCCACGGAATCACCAACGTCGAACCCACGACCGCCGTGGTCTCGATCGTCATCCCGGACCATCCCGCCTCTATTCGGACC
GCGTTTTGCCACCACGTGCACTTCTTCGCCACCCGGGAGGCCGCTGAGCCATGGCTGGCCGAGAACCCCGCGGCCACCGT
CGTTTCCGTGGCTGACGCTTACCAACTCGGCCGCCCCCTGACCCAGTCCCTCCTGAAAGGCACCTCCCCGTCACGCTGCA
CCCAGGTGGGACGATGA

Protein sequence : 
MNPDIAQLAHRLNDSLGGDNPGSTPWMLRPLLDLLAHGAPVTIDQLADATATTVEQVRHALTAMSDTEYDEHGRIIGSGL
TLRPTPHRFDIDGRQLYTWCALDTLIFPGILGRTAHVTSPCHSTGQPVHLTIDTHGITNVEPTTAVVSIVIPDHPASIRT
AFCHHVHFFATREAAEPWLAENPAATVVSVADAYQLGRPLTQSLLKGTSPSRCTQVGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merB BAB47641.1 organomercurial lyase Not tested Type-III SCCmec Protein 5e-58 47
SE0086 NP_763641.1 alkylmercury lyase Not tested SCCpbp4 Protein 3e-58 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merB YP_001840837.1 alkylmercury lyase BAC0663 Protein 3e-56 53
merB YP_001840837.1 alkylmercury lyase BAC0654 Protein 1e-57 52
merB YP_001840837.1 alkylmercury lyase BAC0658 Protein 3e-58 47
merB YP_001840837.1 alkylmercury lyase BAC0659 Protein 4e-39 47
merB YP_001840837.1 alkylmercury lyase BAC0657 Protein 1e-40 42