Gene Information

Name : merA (MMAR_p12)
Accession : YP_001840839.1
Strain :
Genome accession: NC_010604
Putative virulence/resistance : Resistance
Product : mercuric reductase, MerA
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : -
Position : 12901 - 14319 bp
Length : 1419 bp
Strand : -
Note : -

DNA sequence :
ATGGGCTATGACTTGGCGATCATCGGCTCCGGCGGTGCGGCGTTCGCCGCCGCCATCGCCGCCACCACGGCCGGACGCCG
TGTGGTGATGATCGAACGGGCCACCATCGGCGGCACGTGCGTCAACGTCGGATGCGTGCCGTCGAAGGCGCTGCTCGCCG
CCGCCGACGCCCTCCACGGCGCGTCGACCGCGGCCCGGTTTCCAGGCATCGCCGCCAGCGCCGCACCCGTCGACGGCCCG
GCCTTGATGACCGGAAAGGACGCACTGGTCCAGACCCTGCGCGGCGAGAAGTACGTCGACCTCGCCGCCCACTACGGCTG
GGACGTCGTCGAGGGCGACGCCCAGTTCGTCGGCGATGCCGGCGGACCGTGCCTCACCGTCGAAACGCCCGGCGGCGCAA
CGCTGCACGTCGAGGCCGAGCATTATTTGATCGCCACCGGTTCGGCGCCCTGGGCGCCACCCGTCGACGGATTGGCCGAC
ACCGGCTCTCTGACGTCGACCACCGCGATGGACCTAGACCGGCTGCCCGAATCCATGATCGTGCTCGGCGGCGGCTACGT
GGGCCTGGAACAGGCGCAGCTCTTCGCCCGCCTGGGCACCGTGGTCACCGTGGTGACGCGATCACCGCTGCTGTCCGCCG
AAGAACCCGAGGTCTCCGCGGTGCTGGCGGACGTCTTCGGTGACGAGGACATCCGGGTGCACACCCACACCACCGTGACC
GGTGTGCGCCGCGACGAACACGGCTACAGCCTCACCGCCGAACGCGGAACGCAACGGTTGGCGCTGCATGCCGAACAGCT
GCTGGTGGCCACCGGGCGCCGCCCGGTCACCGCCGGTCTGAACCTCGACGCGGTCGGGGTCAAGACCGGTCCGCGCGGAG
AAGTCCTCGTCGACGACCATCTGCGCTCCACCACCGCACGGATCTGGGCTGCCGGCGACGTGACCGGAGGACCGCAGTTC
GTCTACGTCGCCGCGGCCCAGGGCACCCTGGTCGCCGACAACGCGTTCGGCAGGGCCGCCCGCACCCTGGACTACACCGC
CCTGCCGCGGGTCGTGTTCACCAGCCCCGCCGTCGCCTCAGTCGGCATGACCGACGCCCAGGCCACCGCCGCCGGCATCC
AATGCGACTGCCGCACAATACCTTTGCAGTACGTGACGCGGGCAATCGTCAACCGCGACACCCGCGGGTTGGTCAAACTC
GTCGCCGCCGCCGACACCGGTCGGTTACTGGGGGTGCACGTCGTCGCCGAGAACGCCGGAGACGTCATCACCGCCGCCAC
CTACGCGCTGACCGCGGGGATGACCGTCGAGCAGCTCGCCCACACCTGGGCCCCGTATCTGACCATGGCCGAATCACTCA
AACTCGCCGCCCAGGCCTACACCACCGACGTCGCCACCCTGTCCTGCTGCGCCAGCTGA

Protein sequence :
MGYDLAIIGSGGAAFAAAIAATTAGRRVVMIERATIGGTCVNVGCVPSKALLAAADALHGASTAARFPGIAASAAPVDGP
ALMTGKDALVQTLRGEKYVDLAAHYGWDVVEGDAQFVGDAGGPCLTVETPGGATLHVEAEHYLIATGSAPWAPPVDGLAD
TGSLTSTTAMDLDRLPESMIVLGGGYVGLEQAQLFARLGTVVTVVTRSPLLSAEEPEVSAVLADVFGDEDIRVHTHTTVT
GVRRDEHGYSLTAERGTQRLALHAEQLLVATGRRPVTAGLNLDAVGVKTGPRGEVLVDDHLRSTTARIWAAGDVTGGPQF
VYVAAAQGTLVADNAFGRAARTLDYTALPRVVFTSPAVASVGMTDAQATAAGIQCDCRTIPLQYVTRAIVNRDTRGLVKL
VAAADTGRLLGVHVVAENAGDVITAATYALTAGMTVEQLAHTWAPYLTMAESLKLAAQAYTTDVATLSCCAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
merA AAN62178.1 mercuric (Hg(II)) reductase Not tested PAGI-2(C) Protein 2e-72 46
SE0085 NP_763640.1 dihydrolipoamide dehydrogenase Not tested SCCpbp4 Protein 1e-87 45
merA BAB47642.1 mercuric reductase Not tested Type-III SCCmec Protein 9e-88 45
merA AET25397.1 MerA Not tested PAGI-2(C) Protein 2e-69 45
merA AFG30120.1 MerA Not tested PAGI-2 Protein 2e-69 45
merA YP_006098387.1 mercuric ion reductase Not tested Tn2411 Protein 2e-69 45
merA ABQ57371.1 MerA Not tested SGI1 Protein 3e-72 45
merA AGK07021.1 MerA Not tested SGI1 Protein 3e-72 45
merA AGK07079.1 MerA Not tested SGI1 Protein 3e-72 45
unnamed ABR13401.1 mercuric reductase Not tested PAGI-5 Protein 4e-69 44
merA ACN81005.1 MerA Hg(II) mercuric ion reductase Not tested AbaR5 Protein 9e-69 43
merA CAJ77060.1 Mercuric ion reductase Not tested AbaR1 Protein 1e-68 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merA YP_001840839.1 mercuric reductase, MerA BAC0224 Protein 5e-90 47
merA YP_001840839.1 mercuric reductase, MerA BAC0651 Protein 5e-88 45
merA YP_001840839.1 mercuric reductase, MerA BAC0652 Protein 9e-72 45
merA YP_001840839.1 mercuric reductase, MerA BAC0653 Protein 2e-71 44
merA YP_001840839.1 mercuric reductase, MerA BAC0650 Protein 3e-71 44