Gene Information

Name : thiC (LEPBI_I2303)
Accession : YP_001839674.1
Strain :
Genome accession: NC_010602
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2371675 - 2373249 bp
Length : 1575 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGTGATTCCGGCCAAGGAAGTCTCATGTCTCAAAACCATTCAAACCATTCGCCTATAAAGGAAATGTTTACACCAGA
AACGACCATTCCTTTGTCGGATGGAACCGAATACAAAACCTACCGCACAGAAGGGATGTATTGTATCCATGAAGAAACGT
ATGATTACAAACAAGGGATCCCGAAACTGAGAAAACCTTGGGTTGATGTTAGGGAAAGTAGGGGAGATCAAAATGTTTCC
CAACTCTATTATGCAAAAAGAAACATCATCACAGAAGAGATGTTATATGTTGCCAAACGTGAAGGTATGAGTCCTGAATT
TGTATTGAATGAAGTCAAAATTGGTCGTGCCATCATTCCATCTAACAAACGCCATTTGGAATTGGAACCCATGATCATTG
GAAAAAAGTTTCTAGTGAAAATCAATGCCAATATTGGAAATTCGGCCATTCTGTCTTCGATTGATGATGAAGTGGAAAAA
CTACGTTGGGCCTTACATTGGGGTGCCGATACCGTGATGGACCTCTCCACTGGCAAGAATATCCACGAAACAAGGGAATG
GATCATTCGGAATTCGCCAGTTCCCATTGGAACTGTTCCTTTGTACCAAACCTTGGAAAAGGTAAAGGGTAAAGTAGAAG
ATTTAAATATTGGAGTATTCCTCGAAACCTTGGAAGAGCAGGCAGAACAAGGTGTGGATTATTTTACCATCCATGCAGGG
GTGTTACGTGACTATGTCCGGCTCACAGAAAATCGAATCACAGGCATTGTTTCGAGGGGTGGTTCCATTTTGGCGAAGTG
GTGTAACCATCATAAAAAAGAAAACTTTTTGTATGAACATTTTGATGAAATCTCAAAAGTCATGCAAAAATATGGAGTTT
CTTACTCGTTAGGTGATGGGCTAAGGCCAGGTTGTATCAATGATGCCAATGACGCGGCACAATTTGCAGAACTCAAAACC
TTAGGGGAACTCACAAAACGTGCTTGGGCCTTTGACATCCAAGTGATGGTAGAGGGACCAGGCCACGTTCCCATGCACCT
CATCCAAGAAAATGTAAAGTTACAAGAAGAGATCTGTATGGAAGCACCGTTTTATACTCTTGGTCCCCTTGTCACAGACA
TCGCTCCTGGTTATGACCATATCACCTCTGCCATTGGTGCTGCCATGATTGCTTGGTACGGAACCGCTATGCTCTGTTAT
GTGACACCGAAAGAACATTTGGGTCTTCCCAATAAACAAGATGTGAAGGATGGAGTGATTGCTTATAAAATTGCAGCTCA
TGCCGCAGACCTTGCCAAGGGCCACCCAGGTGCGAAGGAACGAGATGATTTGCTGAGCAAAGCTCGGTTTGAATTTCGTT
GGGAAGACCAGTTTGCACTCTCACTCGATCCTGAACTGGCAAGGTCATACCACGACGAGTCCCTCCCGCAGGATGGAATG
AAAAAGGCACATTTCTGTTCGATGTGTGGGCCTCATTTTTGTTCGATGCGACTCACATCCGACTTACGGAAAGATACCGT
TGGTGTCAGCGGAGAAGTTGGTTCAAAGGAAAGAGGAGAGGAAGGAAAGGGATAG

Protein sequence :
MSDSGQGSLMSQNHSNHSPIKEMFTPETTIPLSDGTEYKTYRTEGMYCIHEETYDYKQGIPKLRKPWVDVRESRGDQNVS
QLYYAKRNIITEEMLYVAKREGMSPEFVLNEVKIGRAIIPSNKRHLELEPMIIGKKFLVKINANIGNSAILSSIDDEVEK
LRWALHWGADTVMDLSTGKNIHETREWIIRNSPVPIGTVPLYQTLEKVKGKVEDLNIGVFLETLEEQAEQGVDYFTIHAG
VLRDYVRLTENRITGIVSRGGSILAKWCNHHKKENFLYEHFDEISKVMQKYGVSYSLGDGLRPGCINDANDAAQFAELKT
LGELTKRAWAFDIQVMVEGPGHVPMHLIQENVKLQEEICMEAPFYTLGPLVTDIAPGYDHITSAIGAAMIAWYGTAMLCY
VTPKEHLGLPNKQDVKDGVIAYKIAAHAADLAKGHPGAKERDDLLSKARFEFRWEDQFALSLDPELARSYHDESLPQDGM
KKAHFCSMCGPHFCSMRLTSDLRKDTVGVSGEVGSKERGEEGKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 6e-160 62
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 6e-160 62
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 3e-147 59