Gene Information

Name : serS (SPCG_0410)
Accession : YP_001835127.1
Strain : Streptococcus pneumoniae CGSP14
Genome accession: NC_010582
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 405984 - 407342 bp
Length : 1359 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGCACACCTGTGAAGTTGGATGGAACCGTGGCCCTGCCACTCCAACGTTTTGTCAAGCGTGCTTTTTTCATAAAGGAGT
TCTTATGTTAGATATCAAACGTATTCGTACAGATTTTGAAGCTGTCGCAGAAAAATTAGCTACACGTGGTGTAGATGCTG
CTGTCTTGAATGAAATGAAAGAAATCGATGCTAAACGTCGTAACATCTTGATTAAGGTTGAAACTCTCAAAGCAGAACGT
AACACAGTTTCTGCTGAGATTGCCCAAGCTAAGCGCAACAAGGAAAATACAGATGACAAGATTGCTGCCATGCAAAATCT
ATCTGCTGAGGTTAAAGCCTTGGATGCTGAATTGGCAGAAATCGATGCTAAATTGACAGAATTTACAACGACTCTTCCAA
ATATCCCAGCTGACAGCGTTCCTGTTGGGGCTGACGAAGACGACAATGTGGAAGTTCGCCGTTGGGGTACTCCACGCGAG
TTTGACTTCGAACCTAAAGCTCACTGGGATCTCGGTGAAGACCTTGGTATCCTTGACTGGGAACGCGGTGGTAAGGTAAC
AGGCGCTCGCTTCCTCTTCTATAAAGGCCTCGGTGCTCGTTTGGAACGTGCTATCTACAACTTTATGTTGGATGAACATG
GAAAAGAAGGCTATACTGAAGTCATCACACCTTACATAGTCAACCATGATTCTATGTTTGGTACTGGTCAGTATCCAAAA
TTTAAGGAAGATACTTTTGAACTCAGCGATACCAACTTTGTCTTGATTCCAACTGCTGAAGTTCCTCTGACAAACTACTA
CCGTGATGAAATCTTAGACGGCAAAGATCTTCCAATCTACTTCACTGCCATGAGTCCGTCATTCCGTTCTGAGGCTGGTT
CTGCCGGTCGTGATACGCGTGGCTTGATCCGTTTGCACCAATTCCACAAGGTTGAAATGGTCAAATTTGCCAAACCAGAA
GAATCTTACGAAGAATTGGAAAAAATGACAGCCAACGCTGAAAACATTCTTCAAAAACTCAACCTTCCATACCGTGTCGT
TGCTCTCTCTACTGGAGATATGGGCTTCTCAGCTGCGAAGACTTACGACTTGGAAGTGTGGATTCCAGCACAAAACAATT
ACCGTGAAATCTCAAGCTGTTCAAACACAGAAGATTTCCAAGCCCGTCGTGCCCAAATCCGTTACCGTGATGAAGCAGAT
GGCAAGGTGAAACTCCTTCATACCTTGAACGGTTCTGGACTTGCAGTTGGACGTACAGTGGCTGCAATTCTTGAAAATTA
CCAAAATGAAGATGCTTCTGTGACCATCCCAGAAGCACTTCGTCCATACATGGGTGGAGCTGAAGTCATCAAACCATAA

Protein sequence :
MHTCEVGWNRGPATPTFCQACFFHKGVLMLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIKVETLKAER
NTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTTTLPNIPADSVPVGADEDDNVEVRRWGTPRE
FDFEPKAHWDLGEDLGILDWERGGKVTGARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPK
FKEDTFELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPE
ESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTYDLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEAD
GKVKLLHTLNGSGLAVGRTVAAILENYQNEDASVTIPEALRPYMGGAEVIKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 0.0 97