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Name : tktA (SPCG_1995) Accession : YP_001836712.1 Strain : Streptococcus pneumoniae CGSP14 Genome accession: NC_010582 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : - Position : 1981749 - 1983725 bp Length : 1977 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGTCAAATCTATCTGTTAATGCAATTCGTTTTCTAGGTATTGACGCCATTAATAAAGCCAACTCAGGTCATCCAGGTGT GGTTATGGGAGCGGCTCCGATGGCTTACAGCCTCTTTACAAAACAACTTCATATCAATCCAGCTCAACCAAACTGGATTA ACCGCGACCGCTTTATTCTTTCAGCAGGTCATGGTTCAATGCTCCTTTATGCTCTTCTTCACCTTTCTGGTTTTGAAGAT GTCAGCATGGATGAGATTAAGAGTTTCCGTCAATGGGGTTCAAAAACACCAGGTCACCCAGAATTTGGTCATACGGCAGG GATTGATGCTACGACAGGTCCTCTAGGGCAAGGGATTTCAACTGCTACTGGTTTTGCCCAAGCAGAACGTTTCTTGGCAG CCAAATATAACCGTGAAGGTTACAATATCTTTGACCACTATACTTACGTTATCTGTGGAGACGGAGACTTGATGGAAGGT GTCTCAAGCGAGGCAGCTTCATACGCAGGCTTGCAAAAACTTGATAAGTTGGTTGTTCTTTATGATTCAAATGATATCAA CTTGGATGGTGAGACAAAGGATTCCTTTACAGAAAGTGTTCGTGACCGTTACAATGCCTACGGTTGGCATACTGCCTTGG TTGAAAATGGAACAGACTTGGAAGCCATCCATGCTGCTATCGAAACAGCAAAAGCTTCAGGCAAGCCATCTTTGATTGAA GTGAAGACGGTTATTGGATACGGTTCTCCAAACAAACAAGGAACTAATGCTGTACACGGCGCCCCTCTTGGAGCAGATGA AACTGCATCAACTCGTCAAGCCCTCGGTTGGGACTACGAACCATTTGAAATTCCAGAACAAGTATATGCTGATTTCAAAG AACATGTTGCAGACCGTGGCGCATCAGCTTATCAAGCTTGGACTAAATTAGTTGCAGATTATAAAGAAGCTCATCCAGAA CTGGCTGCAGAAGTAGAAGCCATCATCGACGGACGTGATCCAGTCGAAGTGACTCCAGCAGACTTCCCAGCTTTAGAAAA TGGTTTTTCTCAAGCAACTCGTAATTCAAGTCAAGATGCCTTGAATGTTGTGGCAGCTAAATTACCAACCTTCCTAGGTG GATCAGCTGACCTTGCTCACTCAAACATGACTTATATCAAGACGGATGGACTTCAAGACGATACCAATCGCTTGAATCGT AACATTCAGTTTGGTGTTCGTGAATTTGCAATGGGAACAATCTTGAACGGGATGGCCCTTCATGGTGGACTTCGTGTATA CGGTGGAACTTTCTTCGTCTTCTCTGACTATGTGAAGGCAGCTGTCCGCTTGTCAGCCTTACAAGGACTTCCTGTGACTT ATGTCTTTACCCATGATTCAATCGCAGTTGGGGAAGATGGTCCGACTCATGAACCAGTTGAGCATTTAGCAGGTCTTCGT GCTATGCCAAATCTAAATGTTTTCCGTCCAGCAGATGCGCGTGAAACGCAAGCAGCTTGGTACCTTGCAGTGACAAGTGA GAAAACACCAACTGCCCTTGTCTTGACACGTCAAAATTTGACTGTTGAAGATGGAACAGACTTCTTTAAGGTTGCTAAAG GTGCTTATGTTGTATATGAAAATGCAGCCGACTTTGATACCATCTTGATTGCGACAGGTTCAGAGGTTAATCTTGCTGTC TCAGCTGCTAAAGAATTGGCTAGTCAAGGCGAAAAAATCCGCGTAGTCAGCATGCCATCTACAGATGTCTTTGATAAACA AGATGCAGCTTACAAGGAAGAGATTCTTCCAAATGCAGTCCGCCGTCGTGTTGCAGTCGAAATGGGTGCAAGTCAAAACT GGTACAAATATGTTGGTCTCGATGGTGCCGTTCTAGGTATTGATACCTTCGGAGCCTCTGCCCCAGCACCAAAAGTATTG GCAGAATATGGCTTTACTGTAGAAAATCTTGTAAAAGTTGTTCGAAACTTGAAATAA Protein sequence : MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLHINPAQPNWINRDRFILSAGHGSMLLYALLHLSGFED VSMDEIKSFRQWGSKTPGHPEFGHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGTDLEAIHAAIETAKASGKPSLIE VKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALGWDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPE LAAEVEAIIDGRDPVEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQDDTNRLNR NIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGLPVTYVFTHDSIAVGEDGPTHEPVEHLAGLR AMPNLNVFRPADARETQAAWYLAVTSEKTPTALVLTRQNLTVEDGTDFFKVAKGAYVVYENAADFDTILIATGSEVNLAV SAAKELASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAVLGIDTFGASAPAPKVL AEYGFTVENLVKVVRNLK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 4e-154 | 50 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 3e-147 | 48 |
