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Name : secA (SPCG_1674) Accession : YP_001836391.1 Strain : Streptococcus pneumoniae CGSP14 Genome accession: NC_010582 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 1649630 - 1652143 bp Length : 2514 bp Strand : - Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGCTAATATTTTAAAAACAATTATCGAAAATGATAAAGGAGAAATCCGTCGTCTGGAAAAGATGGCTGACAAGGTTTT CAAATACGAAGACCAAATGGCTGCTTTGACTGACGACCAACTAAAAGCAAAAACAGTTGAATTTAAGGAACGTTATCAAA ATGGAGAATCACTGGATTCATTGCTTTACGAAGCATTTGCGGTTGTCCGTGAAGGTGCCAAACGTGTCCTAGGTCTCTTC CCTTATAAGGTTCAGGTCATGGGGGGGATTGTTCTTCACCATGGTGACGTGCCAGAGATGCGTACAGGGGAAGGGAAAAC CTTGACTGCGACCATGCCGGTATACCTCAATGCCCTTTCAGGTAAAGGGGTTCACGTAGTTACGGTTAATGAATACCTGT CAGAACGTGACGCGACTGAGATGGGTGAATTGTACTCTTGGCTTGGTTTGTCAGTAGGGATTAACTTGGCTACCAAATCT CCAATGGAGAAAAAAGAAGCCTATGAGTGTGATATTACTTACTCAACTAACTCAGAAATCGGATTTGACTACCTTCGTGA CAATATGGTCGTTCGCGCTGAAAACATGGTACAACGTCCGCTTAACTATGCCTTGGTCGATGAGGTTGACTCTATCTTGA TTGACGAGGCTCGTACACCTTTGATTGTATCAGGTGCCAATGCGGTTGAAACCAGTCAGTTGTATCACATGGCAGACCAC TATGTAAAATCTTTGAACAAAGATGACTACATCATCGATGTGCAGTCTAAGACTATTGGTTTGTCTGATTCAGGGATTGA CAGGGCTGAAAGCTACTTCAAACTTGAAAACCTCTATGACATCGAAAACGTGGCTTTGACCCACTTTATCGATAACGCCC TTCGTGCCAACTACATCATGCTTCTCGATATTGACTATGTGGTGAGCGAAGAGCAAGAAATCTTGATTGTCGACCAATTT ACAGGTCGTACCATGGAAGGTCGTCGTTATTCTGATGGATTGCACCAAGCTATTGAAGCCAAAGAAGGTGTGCCAATCCA GGATGAAACCAAGACATCTGCCTCAATCACGTACCAAAACCTTTTCCGTATGTACAAAAAATTGTCTGGTATGACGGGTA CAGGTAAGACTGAGGAAGAAGAATTTCGTGAAATCTACAACATTCGTGTTATTCCAATCCCAACAAACCGTCCTGTTCAA CGTATTGACCACTCAGACCTTCTTTATGCAAGTATAGAATCTAAGTTTAAAGCGGTTGTCGAAGACGTTAAGGCTCGTTA CCAAAAGGGTCAACCTGTCTTGGTTGGTACAGTAGCGGTTGAAACTAGTGACTACATTTCTAAGAAATTGGTTGCAGCTG GTGTTCCTCACGAAGTCTTGAATGCCAAAAACCACTATAGAGAAGCCCAAATCATCATGAATGCTGGTCAACGTGGTGCC GTTACCATCGCAACCAACATGGCGGGTCGTGGTACCGACATCAAGCTTGGTGAAGGTGTTCGTGAACTTGGAGGACTTTG TGTTATTGGTACAGAACGTCATGAAAGTCGTCGTATCGATAACCAGCTTCGTGGACGTTCAGGTCGTCAAGGAGATCCAG GTGAGTCACAATTCTACCTATCTCTTGAAGATGATTTGATGAAACGTTTTGGTTCTGAACGCTTGAAGGGAATCTTTGAA CGCTTGAACATGTCTGAAGAGGCGATTGAGTCTCGCATGTTGACGCGTCAGGTTGAAGCAGCTCAGAAACGTGTCGAAGG AAATAACTACGATACCCGTAAACAAGTCCTTCAATACGATGATGTCATGCGTGAACAACGTGAGATTATCTATGCTCAAC GTTACGATGTCATCACTGCAGATCGTGACTTGGCACCTGAAATTCAGTCTATGATCAAACGCACGATTGAACGTGTCGTT GATGGTCATGCGCGTGCCAAACAAGATGAAAAACTAGAGGCAATTTTGAACTTTGCTAAGTACAACTTGCTTCCTGAAGA TTCTATTACGATGGAAGACTTGTCAGGCTTGTCTGATAAGGCCATCAAGGAAGAGCTTTTCCAACGTGCCTTGAAGGTTT ACGATAGTCAGGTTTCAAAACTACGCGATGAAGAAGCAGTTAAAGAATTCCAAAAAGTTTTGATTCTACGAGTGGTGGAT AACAAGTGGACAGATCATATCGATGCCCTTGATCAATTGCGTAACGCGGTTGGACTTCGTGGCTATGCTCAGAACAACCC TGTTGTTGAGTATCAGGCAGAAGGTTTCCGTATGTTTAATGATATGATTGGTTCGATTGAGTTTGATGTGACACGCTTGA TGATGAAAGCACAAATTCATGAACAAGAAAGACCACAGGCAGAACGTCATATCAGTACAACAGCGACTCGCAATATCGCT GCTCACCAAGCAAGTATGCCAGAAGATTTGGATTTGAGCCAGATTGGACGCAATGAACTTTGCCCATGTGGTTCTGGTAA GAAATTTAAAAACTGTCACGGTAAAAGACAATAA Protein sequence : MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLF PYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH YVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQF TGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQ RIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFE RLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQSMIKRTIERVV DGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVD NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRNIA AHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 2e-140 | 42 |
