Gene Information

Name : SPCG_1327 (SPCG_1327)
Accession : YP_001836044.1
Strain : Streptococcus pneumoniae CGSP14
Genome accession: NC_010582
Putative virulence/resistance : Resistance
Product : rRNA methylase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0030
EC number : -
Position : 1314900 - 1315637 bp
Length : 738 bp
Strand : +
Note : -

DNA sequence :
ATGAACAAAAATATAAAATATTCTCAAAACTTTTTAACGAGTGAAAAAGTACTCAACCAAATAATAAAACAATTGAATTT
AAAAGAAACCGATACCGTTTACGAAATTGGAACAGGTAAAGGGCATTTAACGACGAAACTGGCTAAAATAAGTAAACAGG
TAACGTCTATTGAATTAGACAGTCATCTATTCAACTTATCGTCAGAAAAATTAAAACTGAACATTCGTGTCACTTTAATT
CACCAAGATATTCTACAGTTTCAATTCCCTAACAAACAGAGGTATAAAATTGTTGGGAATATTCCTTACCATTTAAGCAC
ACAAATTATTAAAAAAGTGGTTTTTGAAAGCCGTGCGTCTGACATCTATCTGATTGTTGAAGAAGGATTCTACAAGCGTA
CCTTGGATATTCACCGAACACTAGGGTTGCTCTTGCACACTCAAGTCTCGATTCAGCAATTGCTTAAGCTGCCAGCGGAA
TGCTTTCATCCTAAACCAAAAGTAAACAGTGTCTTAATAAAACTTACCCGCCATACCACAGATGTTCCAGATAAATATTG
GAAGCTATATACGTACTTTGTTTCAAAATGGGTCAATCGAGAATATCGTCAACTGTTTACTAAAAATCAGTTTCATCAAG
CAATGAAACACGCCAAAGTAAACAATTTAAGTACCATTACTTATGAGCAAGTATTGTCTATTTTTAATAGTTATCTATTA
TTTAACGGGAGGAAATAA

Protein sequence :
MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLI
HQDILQFQFPNKQRYKIVGNIPYHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHAKVNNLSTITYEQVLSIFNSYLL
FNGRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ermA NP_373288.1 rRNA methylase Not tested Type-II SCCmec Protein 1e-53 52
ermA-3 YP_190052.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 1e-53 52
unnamed BAB47663.1 rRNA adenine N-6-methyltransferase Not tested Type-III SCCmec Protein 3e-53 52
unnamed BAC53825.1 rRNA adenine N-6-methyltransferase Not tested SRImec-III and SCCmec-III region Protein 3e-53 52
ermA BAC57474.1 rRNA methylase Not tested Type-IIIinv SCCmec Protein 1e-53 52
ermA BAA82205.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 1e-53 52
ermA1 YP_039522.1 rRNA adenine N-6-methyltransferase 1 Not tested Type-II SCCmec Protein 1e-53 52
ermA NP_370576.1 rRNA methylase Not tested Type-II SCCmec Protein 1e-53 52
ermC NP_273130.1 rRNA adenine N-6-methyltransferase Not tested IHT-A Protein 6e-57 51

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPCG_1327 YP_001836044.1 rRNA methylase AM410044.gene14.p01 Protein 3e-112 99
SPCG_1327 YP_001836044.1 rRNA methylase AM903082.gene3.p01 Protein 3e-112 99
SPCG_1327 YP_001836044.1 rRNA methylase AM180355.1.gene2254. Protein 3e-110 98
SPCG_1327 YP_001836044.1 rRNA methylase AM180355.1.gene2259. Protein 3e-110 98
SPCG_1327 YP_001836044.1 rRNA methylase M64090.gene.p01 Protein 5e-56 53
SPCG_1327 YP_001836044.1 rRNA methylase AJ313523.1.orf0.gene Protein 2e-53 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_009782.5559087.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002758.1121630.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002952.2859615.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002745.1123579.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002745.1124852.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_009782.5559229.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002758.1120012.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002952.2859614.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002745.1122822.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002745.1124324.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase NC_002745.1125313.p0 Protein 7e-54 52
SPCG_1327 YP_001836044.1 rRNA methylase V01278.gene.p01 Protein 3e-58 52
SPCG_1327 YP_001836044.1 rRNA methylase M15332.gene.p01 Protein 5e-53 51
SPCG_1327 YP_001836044.1 rRNA methylase NC_007209.3523503.p0 Protein 3e-57 51
SPCG_1327 YP_001836044.1 rRNA methylase NC_007792.3912746.p0 Protein 1e-56 51
SPCG_1327 YP_001836044.1 rRNA methylase NC_010686.6295746.p0 Protein 3e-57 51
SPCG_1327 YP_001836044.1 rRNA methylase NC_010685.6295744.p0 Protein 3e-57 51