Gene Information

Name : nrdF (SPCG_1117)
Accession : YP_001835834.1
Strain : Streptococcus pneumoniae CGSP14
Genome accession: NC_010582
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 1086742 - 1087704 bp
Length : 963 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence : 
ATGGAAACTTACTACAAAGCCATTAACTGGAATGCCATCGAAGATGTCATCGACAAATCAACTTGGGAAAAACTGACGGA
GCAATTTTGGCTCGATACACGTATTCCCTTATCAAACGACTTGGATGACTGGAGAAAGCTATCTAACAAAGAGAAAGACT
TGGTCGGAAAAGTTTTTGGTGGTTTAACCCTTCTTGACACTATGCAATCTGAAACTGGGGTTCAAGCCCTTCGCGCAGAC
ATCCGTACACCACATGAGGAAGCTGTTTTCAATAACATCCAATTTATGGAATCTGTCCACGCTAAATCTTACTCATCAAT
CTTTTCTACCTTGAATACTAAGGCTGAGATTGAAGAAATTTTCGAATGGACCAATACCAATCCTTACCTACAAAAGAAGG
CTGAGATTGTCAACGAAATCTACCTAAACGGCAGCCCACTTGAAAAGAAAGTTGCCAGCGTCTTCCTCGAAACCTTCCTC
TTCTACTCTGGTTTCTTCACTCCCCTCTACTATCTCGGTAACAACAAACTAGCCAACGTTGCAGAAATCATTAAATTGAT
TATTCGTGACGAGTCTGTTCACGGAACCTACATTGGTTACAAATTCCAACTTGGTTTCAATGAATTGCCTGAAGAAGAGC
AAGAAAAACTCAAAGAATGGATGTACGACCTACTCTATACTCTTTATGAAAATGAAGAAGGCTACACAGAGAGTCTTTAT
GACGGTGTTGGTTGGACTGAAGAGGTTAAAACCTTCCTTCGCTACAATGCCAATAAAGCTCTCATGAACATGGGACAAGA
TCCACTTTTCCCAGATTCAGCTGAAGATGTCAACCCAATCGTTATGAACGGTATTTCAACAGGAACTTCCAACCATGACT
TCTTCTCTCAAGTCGGAAATGGTTACCTTCTTGGCGAAGTTGAAGCCATGCAAGATGATGACTACAACTACGGTTTGGAC
TAA

Protein sequence : 
METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRAD
IRTPHEEAVFNNIQFMESVHAKSYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLKEWMYDLLYTLYENEEGYTESLY
DGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAEDVNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 8e-72 50