Gene Information

Name : alr (XfasM23_1923)
Accession : YP_001830597.1
Strain : Xylella fastidiosa M23
Genome accession: NC_010577
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 2143471 - 2144559 bp
Length : 1089 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
GTGCGTCCCGCCCACGCCGTAATTGATCTGGATGCGTTACGTCACAATTATCGATTTGCTCGCCGTCTTGGCGGTGGCAA
GGCGTTAGCTGTGGTGAAAGCCGATGCGTATGGTCACGGTGCGGTGCGTTGTGCGCAGGCTTTGGAGGCTGAAGTTGATG
GTTTTGCGGTGGCGTGTATCGAAGAGGCGTTGGAGTTACGCCAAGCCGGTATCCAGGCACCGATCCTGTTGCTGGAAGGA
TTTTTCGAGGTTGAAGAGCTGGAATTGATTGCTAAGCACAATTTATGGACTGTGATTGCTTCGTCCTGGCAGGTGCGGGC
GTTGGCTGCGTTCCACAGTCCATCTCCAATTGGGGTGTGGCTTAAGTTGGATAGTGGCATGCATCGGCTTGGTTTGGAGC
CAAAGGAGTTTCGTGATGCTTGGATGTCTCTGCATAGTCTGCCGCAGGTGGGCGAGGTCGTCTTGATGACGCATTTGGCC
CGTGCTGATGAGTTGGATAATCCTCGTACCAATGAGCAGGCATCGGTTTTTGCACATGCTTCGCAGGGAATGGTGGCGCC
AGCAAGTGTGTGTAACTCTTCAGGTTTGCTTGGTTGGGCAGGGTTGTACAGTGATTGGGGTCGGCCCGGGTTAATGTTGT
ACGGTGTCAATCCTATTTCGCAGGAGAGCACGTCACTTAGTGGGCCATTGCGTCCTGTGATGATGGTGTATTCCAAGCTG
ATTGCGGTACGCGAGTTGCCTGCCGGCGAGCCAGTTGGCTATGGGGCATCCTTTGTCACTGAGCGGCCAACCCGGGTTGG
TGTGGTAGCGATGGGCTATGCAGACGGTTACCCGTATTTTGCGGTCAATGGTACGCCGCTCTTGGTTGATGGGCGTGTTT
GTCCGTTGATCGGCCGGGTTTCTATGGACATGTTGACGGTTGATCTGACAGACCATCCGCAGGCGGATGTTGGCAGTCAA
GTGCAATTGTGGGGTGTGCAACCGGGTGTGGCTGAACTTGCGGCACATTGTAATTTGAGCGCTTATCAGTTGTTGTGCGG
TCTTAAGCGTGTACGTCGATACTATTTGGGTGAGATGGGCGCAGTGTGA

Protein sequence :
MRPAHAVIDLDALRHNYRFARRLGGGKALAVVKADAYGHGAVRCAQALEAEVDGFAVACIEEALELRQAGIQAPILLLEG
FFEVEELELIAKHNLWTVIASSWQVRALAAFHSPSPIGVWLKLDSGMHRLGLEPKEFRDAWMSLHSLPQVGEVVLMTHLA
RADELDNPRTNEQASVFAHASQGMVAPASVCNSSGLLGWAGLYSDWGRPGLMLYGVNPISQESTSLSGPLRPVMMVYSKL
IAVRELPAGEPVGYGASFVTERPTRVGVVAMGYADGYPYFAVNGTPLLVDGRVCPLIGRVSMDMLTVDLTDHPQADVGSQ
VQLWGVQPGVAELAAHCNLSAYQLLCGLKRVRRYYLGEMGAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 1e-52 43