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Name : leuS (SGR_4973) Accession : YP_001826485.1 Strain : Streptomyces griseus NBRC 13350 Genome accession: NC_010572 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 5866612 - 5869485 bp Length : 2874 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAGCGAGACGAATTCCGCCGCCGAGACGGCCGCGCCGCACCGCTACACGGCGGCGATGGCCGCCGACATCGAGGCACG CTGGCAGGACTTCTGGGACGCCGAGGGGACCTACGAGGCGCCGAACCCCACCGGTGACCTGGCGGGCGACCCGGAGCTGG CCGCCAGGCCGAAGAAGTTCATCATGGACATGTTCCCGTACCCCTCGGGCGCGGGGCTGCACGTCGGACACCCCCTGGGC TACATCGCCACCGATGTCTACGCCCGCCACCAGCGGATGACCGGCCACAACGTGCTGCACACCCTGGGCTTCGACGCGTT CGGCCTGCCCGCCGAACAGTACGCGGTGCAGACGGGCACCCACCCCCGGGTCTCCACCGAGGCCAACATGGAGAACATGA AGGTCCAGCTGCGCCGGCTGGGTCTGGGCCACGACAACCGCCGCTCCTTCGCGACGATCGACTCCGAGTACTACAAGTGG ACGCAGTGGATCTTCCTGCAGATCTTCAACTCCTGGTACGACTCCGAGGCCGACAGGGCCCGTCCGATCGCCGAGCTGGT CGAGCAGTTCGAGAACGGCACGCGCGCGACCCCCGACGGCCGTGAGTGGGGGGCGCTGAGCGCCGCCGAGCGCGCCGACC TGCTGAGCGAGTACCGCCTGGCGTACGCCTCCGACGCCCCGGTGAACTGGTCGCCCGGCCTGGGCACCGTCCTGGCCAAC GAGGAGGTCACCGCCGACGGCCGTTCCGAGCGCGGCAACTTCCCCGTCTTCAAGGCCAAGCTGCGCCAGTGGAACATGCG CATCACCGCCTACGCCGACCGGCTGCTGAACGACCTGGACGGGCTGGACTGGCCCGAGGCCATCAAGCTGCAGCAGCGCA ACTGGATCGGCCGCTCCGAGGGCGCCCGGGTCGAGTTCCCGGTGGACACCGCGGGCGGCATCACCGTCTTCACCACCCGC CAGGACACCCTGTTCGGCGCGACGTACATGGTCCTGGCGCCCGAGCACGACATGGTGGAGCGGATCATTCCGGCCGCCTG GCCCGAGGGCACCCACCCGGTGTGGACGGGCGGCCACGCGAGCCCGGCCGAGGCCGTCACCGCGTACCGCAAGCAGGCCG CCGCCAAGTCCGACGTCGAGCGGCAGGCCGAGGCCAAGGACAAGACCGGTGTCTTCACCGGCGCGTACGCGACCAACCCG GTCAGCGGCGAGAAGGTCCCCGTCTTCATCGCCGACTACGTCCTGATGGGCTACGGCACCGGCGCGATCATGGCCGTACC GGCGCACGACGCGCGCGACTTCGCCTTCGCGCGCGCCTTCGAGCTGCCGATGCGCTGTGTCGTCCAGCCCTCCGACGACC GCGGCACCGACCCCGCCACGTGGGACGACGCCTTCAGCTCGTACGACGCGAAGCTGGTCAACTCCGCCAACGACGAGATC TCGCTGGACGGCCTGGGCGTCGTGGAGGCCAAGGCGAGGATCACCGAGTGGCTGAAGGAGCACGGCGTCGGCGAGGGCAC CGTCAACTTCCGGCTGCGCGACTGGCTGTTCAGCCGGCAGCGCTACTGGGGCGAGCCCTTCCCGATCGTGTACGACGAGG ACGGCATCGCCCACCCGCTGCCCGAGTCGATGCTGCCGCTGGAGCTGCCCGAGGTCGAGGACTACTCCCCGCGCACCTTC GACCCGGAGGACGCGACAGCCCAGCCCGAGACCCCGCTGTCGCGCAACGCTGACTGGGTCAACGTCACGCTGGACCTGGG CGACGGCGCCGGTCCGCGGAAGTACCGCCGCGAGACCAACACCATGCCCAACTGGGCCGGTTCCTGCTGGTACGAGCTGC GTTACCTGGACCCGAACAACGACCGTCAGCTGGTCGACCCGTCGATCGAGCAGTACTGGATGGGTCCGCGCGAGGGTCAG CCCACCGGGGGTGTCGACCTGTACGTCGGCGGCGCCGAGCACGCCGTGCTGCACCTGCTGTACGCGCGCTTCTGGTCCAA GGTGCTGCACGACCTGGGCCACATCTCCTCCGCCGAGCCGTTCCACAAGCTGTACAACCAGGGCATGATCCAGGCCTTCG TCTACCGCGACAGCCGGGGCATCGCCGTCCCGGCCGCCGAGGTGGAGGAGCGCGACGGCGCCTTCTACCACGCGGGCGAG AAGGTCAGCCGCGTCCTGGGCAAGATGGGCAAGTCCCTGAAGAACGCGGTCACGCCGGACGAGATCTGCGCGGAGTACGG CGCGGACACCCTGCGCCTGTACGAGATGGCGATGGGCCCCCTGGACGTGTCGCGCCCCTGGGACACCCGGGCCGTGGTCG GCCAGTACCGGCTGCTGCAGCGGCTGTGGCGCAATGTGGTCGACGAGGCGACCGGTGAGGTCACCGTCGTCGACACGGAG CCCGACGAGGACACGCTGCGCGCCCTGCACAAGGCGATCGACGGGGTCGGCCAGGACATGGCGGGGATGCGGTTCAACAC CGCCATCGCCAAGGTCACCGAGCTGAACAACCACCTGACGAAGGCCGGCGGCCCGCTGTCGCGCTCGGTCGCCGAGCGGC TGGTCCTGCTGATCGCCCCGCTGGCCCCGCACATCGCCGAGGAGCTGTGGCGCCGCCTGGGCCACGCCGATTCGGTCGTG CACCAGGACTTCCCGGTGGCCGACCCGGCGTACGTGGTCGACGAGACCGTCACCTGCGTGGTCCAGATCAAGGGCAAGGT CCGGGCCCGCCTGGAGATCTCGCCGGCCATCACGGACGAGGAGCTGGAAGCCCTGGCCCTGGCCGACGAGGCGGTCGTCG CGGCGCTGGGCGGGGCCGGGATCCGCAAGGTGATCGTGCGTGCGCCGAAGCTGGTGAACATCGTTCCCGCGTGA Protein sequence : MSETNSAAETAAPHRYTAAMAADIEARWQDFWDAEGTYEAPNPTGDLAGDPELAARPKKFIMDMFPYPSGAGLHVGHPLG YIATDVYARHQRMTGHNVLHTLGFDAFGLPAEQYAVQTGTHPRVSTEANMENMKVQLRRLGLGHDNRRSFATIDSEYYKW TQWIFLQIFNSWYDSEADRARPIAELVEQFENGTRATPDGREWGALSAAERADLLSEYRLAYASDAPVNWSPGLGTVLAN EEVTADGRSERGNFPVFKAKLRQWNMRITAYADRLLNDLDGLDWPEAIKLQQRNWIGRSEGARVEFPVDTAGGITVFTTR QDTLFGATYMVLAPEHDMVERIIPAAWPEGTHPVWTGGHASPAEAVTAYRKQAAAKSDVERQAEAKDKTGVFTGAYATNP VSGEKVPVFIADYVLMGYGTGAIMAVPAHDARDFAFARAFELPMRCVVQPSDDRGTDPATWDDAFSSYDAKLVNSANDEI SLDGLGVVEAKARITEWLKEHGVGEGTVNFRLRDWLFSRQRYWGEPFPIVYDEDGIAHPLPESMLPLELPEVEDYSPRTF DPEDATAQPETPLSRNADWVNVTLDLGDGAGPRKYRRETNTMPNWAGSCWYELRYLDPNNDRQLVDPSIEQYWMGPREGQ PTGGVDLYVGGAEHAVLHLLYARFWSKVLHDLGHISSAEPFHKLYNQGMIQAFVYRDSRGIAVPAAEVEERDGAFYHAGE KVSRVLGKMGKSLKNAVTPDEICAEYGADTLRLYEMAMGPLDVSRPWDTRAVVGQYRLLQRLWRNVVDEATGEVTVVDTE PDEDTLRALHKAIDGVGQDMAGMRFNTAIAKVTELNNHLTKAGGPLSRSVAERLVLLIAPLAPHIAEELWRRLGHADSVV HQDFPVADPAYVVDETVTCVVQIKGKVRARLEISPAITDEELEALALADEAVVAALGGAGIRKVIVRAPKLVNIVPA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-135 | 49 |
