Gene Information

Name : SGR_4118 (SGR_4118)
Accession : YP_001825630.1
Strain : Streptomyces griseus NBRC 13350
Genome accession: NC_010572
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4810862 - 4813390 bp
Length : 2529 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGCGGCGGGTTGTCGTCCTGGCTCAGGAAGAAGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATTCTCCTGGGCCTGATCCATGAGGGTGAGGGTGTCGCCGCTAAGGCCCTGGAGAGCCTCGGGA
TTTCGCTCGAGGCGGTCCGCCAGCAGGTGGAGGAGATCATCGGGCAGGGCCAGCAGGCTCCGTCCGGGCACATCCCCTTC
ACCCCGCGAGCCAAGAAGGTCCTGGAGCTGTCGCTCCGCGAGGCCCTTCAGCTGGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTCGCCGCCCAGGTCCTCGTGAAGCTGGGCGCCGACCTGAACCGGG
TCCGGCAGCAGGTCATCCAGCTGCTTTCCGGGTACTCGGGCGGCAAGGAGGCGGCCACCGCAGGCGGTCCCGCCGAGGGC
ACGCCCTCCACGTCCCTGGTGCTCGACCAGTTCGGCCGGAATCTCACCCAGGCCGCTCGTGAGTCCAAGCTCGACCCGGT
CATCGGGCGCGAGAAGGAGATCGAGCGGGTCATGCAGGTGCTGTCCCGCCGGACCAAGAACAACCCGGTCCTCATCGGCG
AGCCCGGCGTCGGCAAGACGGCGGTCGTCGAGGGCCTGGCCCAGGCGATCGTCAAGGGCGAGGTGCCCGAGACCCTCAAG
GACAAGCACCTCTACACCCTGGACCTCGGCGCCCTGGTCGCCGGCTCCCGGTACCGGGGTGACTTCGAGGAGCGCCTGAA
GAAGGTCCTCAAGGAGATCCGCACCCGCGGCGACATCATCCTGTTCATCGACGAGCTCCACACGCTCGTCGGCGCGGGTG
CCGCGGAAGGCGCCATCGACGCGGCCTCGATCCTGAAGCCCATGCTGGCGCGCGGTGAGCTCCAGACCATCGGTGCCACC
ACGCTCGACGAGTACCGCAAGCACCTGGAGAAGGACGCCGCTCTCGAGCGCCGCTTCCAGCCCATCCAGGTCGCGGAGCC
GTCGCTGCCGCACACCATCGAGATCCTCAAGGGGCTGCGCGACCGCTACGAGGCCCACCACCGGGTCTCCATCACGGACG
AGGCCCTCGTCCAGGCCGCGACGCTGGCGGACCGGTACATCTCGGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATC
GACGAAGCCGGATCCCGCATGCGCATCCGCCGGATGACCGCGCCGCCGGACCTCCGCGAGTTCGACGAGAAGATCGCGGG
CGTCCGCCGCGACAAGGAGTCGGCCATCGACTCCCAGGACTTCGAGAAGGCGGCTTCCCTCCGCGACAAGGAGAAGCAGC
TGCTGGCGGCGAAGGCCAAGCGGGAGAAGGAGTGGAAGGCCGGCGACATGGACGTCGTCGCCGAGGTCGACGGCGAGCTC
ATCGCCGAAGTCCTGGCCACGGCCACCGGAATCCCGGTCTTCAAGCTGACGGAGGAGGAGTCCTCCCGTCTGCTGCGCAT
GGAGGACGAACTCCACAAGCGCGTCATCGGGCAGAAGGACGCCATCAAGGCCCTTTCGCAGGCGATCCGCCGTACGCGGG
CCGGCCTGAAGGACCCGAAGCGCCCCGGCGGCTCGTTCATCTTCGCCGGCCCCTCCGGTGTCGGTAAGACCGAGCTCTCC
AAGACGCTCGCCGAATTCCTCTTCGGCGACGAGGACGCCCTGATCTCCCTCGACATGTCGGAGTTCAGCGAGAAGCACAC
GGTTTCCCGTCTCTTCGGTTCGCCCCCCGGCTACGTGGGCTACGAGGAGGGCGGGCAGCTCACCGAGAAGGTGCGCCGCA
AGCCGTTCTCCGTCGTCCTCTTCGACGAGGTCGAGAAGGCCCACCCCGATATCTTCAATTCCCTGCTCCAGATTCTGGAG
GACGGTCGCCTGACCGACTCCCAGGGTCGGGTCGTGGACTTCAAGAACACGGTCATCATCATGACGACCAACCTCGGGAC
CCGGGACATCTCGAAGGGCTTCAACCTGGGATTCGCCGCCCAGGGCGACGTCAAGACGAACTACGAGCGGATGAAGACCA
AGGTCAACGAGGAGCTCAAGCAGCACTTCCGGCCGGAATTCCTCAACCGTGTCGACGACACGGTCGTCTTCCACCAGCTG
ACCGAGGAAGACATCATCCAGATCGTCGACCTCATGCTCGCCAAGGTCGACGAGCGTCTCAAGGACCGCGACATGGGCAT
CGAGCTCAGTGGCGAGGCCAAGACGCTGCTCGCGAAGAAGGGCTACGACCCCGTGATGGGCGCCCGGCCGCTGCGCCGGA
CGATCCAGCGGCAGATCGAGGACGTCCTCTCCGAGAAGATCCTCTTCGGTGAGCTGCGTCCCGGTCACATCGTGGTCGTG
GGCACCGAGGGCGAGGGTGACGACAAGACGTTCACCTTCCGCGGCGAGGAGAAGTCGGCTCTGCCCGACGTCCCGCCGAT
CGAGCAGGCGGCGGGCGGCGCCGGCCCGAACCTCACCAAGGACGCGTGA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGISLEAVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVIQLLSGYSGGKEAATAGGPAEG
TPSTSLVLDQFGRNLTQAARESKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVKGEVPETLK
DKHLYTLDLGALVAGSRYRGDFEERLKKVLKEIRTRGDIILFIDELHTLVGAGAAEGAIDAASILKPMLARGELQTIGAT
TLDEYRKHLEKDAALERRFQPIQVAEPSLPHTIEILKGLRDRYEAHHRVSITDEALVQAATLADRYISDRFLPDKAIDLI
DEAGSRMRIRRMTAPPDLREFDEKIAGVRRDKESAIDSQDFEKAASLRDKEKQLLAAKAKREKEWKAGDMDVVAEVDGEL
IAEVLATATGIPVFKLTEEESSRLLRMEDELHKRVIGQKDAIKALSQAIRRTRAGLKDPKRPGGSFIFAGPSGVGKTELS
KTLAEFLFGDEDALISLDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKPFSVVLFDEVEKAHPDIFNSLLQILE
DGRLTDSQGRVVDFKNTVIIMTTNLGTRDISKGFNLGFAAQGDVKTNYERMKTKVNEELKQHFRPEFLNRVDDTVVFHQL
TEEDIIQIVDLMLAKVDERLKDRDMGIELSGEAKTLLAKKGYDPVMGARPLRRTIQRQIEDVLSEKILFGELRPGHIVVV
GTEGEGDDKTFTFRGEEKSALPDVPPIEQAAGGAGPNLTKDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 75

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SGR_4118 YP_001825630.1 ATP-dependent Clp protease VFG0079 Protein 0.0 61
SGR_4118 YP_001825630.1 ATP-dependent Clp protease VFG0080 Protein 9e-151 53