Gene Information

Name : SGR_3653 (SGR_3653)
Accession : YP_001825165.1
Strain : Streptomyces griseus NBRC 13350
Genome accession: NC_010572
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4272374 - 4274194 bp
Length : 1821 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACCACAGCGGACGCACGCACGCCTGCCTCGAAACAGAACGACGGAACGCCGGACGGCACGACGCCGGACGCCGGGAC
GCCGAACGACGGGGCCGGGAAGTCCATCGGCTGGCACAAGGGGTACGTCCAGGGCTCGCGCCCGGACCTCCGGGTGCCGG
TCCGACAGGTGCACCTCACCAACGGCAAGCACGTGACGCTGTACGACACGTCCGGGCCGTACACCGACGCCTCCGTCGAC
ACCGATGTCCGCCGCGGCCTCGCGCCCCTGCGGGAGAACTGGATCATCGCCCGCGGCGACACCGAGGAGTACGCGGGCCG
GCCGGTCCGCCCCGAGGACGACGGGCTCAAGCACACCTCGCCGCGCGGCGGGCTGCGCAACCTCGACGCGGTCTTCCCCG
GCCGCCCGCGCCAGCCGCGCCGCAGCCGCGACGGACGGCCCGTCACCCAGCTCGCGTACGCCCGGCGGGGGGAGGTCACC
CCGGAGATGGAGTACGTGGCGATCCGGGAGAACGTCGAGGCCGAGGTCGTCCGCGAGGAGATCGCGGCGGGCCGGGCGGT
GCTGCCGGCCAACGTCAACCACCCCGAGATCGAGCCGATGATCATCGGCAAGCGGTTCCTGGTGAAGGTCAACGCCAACA
TCGGCAACTCGGCCGTCACCTCGTCCATCGAGGAGGAGGTGGACAAGATGACCTGGGCGACCCAGTGGGGCGCCGACACG
GTCATGGACCTGTCCACCGGCCGCAACATCCACACCACCCGCGAGTGGGTGCTGCGCAACTCCCCCGTGCCGATCGGCAC
CGTTCCGCTCTACCAGGCCCTGGAGAAGGTCGACGGCCGGGCCGAGGAACTGACCTGGGAGATCTACAAGGACACCGTCA
TCGAGCAGGCCGAGCAGGGCGTGGACTACATGACGGTGCACGCCGGAGTGCGCCTGCCGTACGTCCCGCTGACGGCCCGT
CGCAAGACCGGGATCGTCTCGCGCGGCGGCTCGATCATGGCGGCCTGGTGCCTCGCCCACCACAAGGAGTCGTTCCTCTA
CGAGCACTTCGAGGAGCTCTGCGAGATCCTCGCGACGTACGACGTCACGTACTCGCTGGGCGACGGGCTGCGGCCCGGGT
CGATCGCGGACGCCAACGACGAGGCGCAGTTCGCGGAGCTGCGCACGCTGGGCGAGCTGAACACGGTCGCGAAGCGGTTC
GGGGTCCAGACCATGATCGAGGGTCCCGGACACGTCCCGATGCACAAGATCAAGGAGAACATCGACCTCCAGCAGGAGAT
CTGCGAGGAGGCGCCGTTCTACACGCTCGGCCCGCTGACCACGGATGTCGCGCCCGCCTACGACCACATCACCTCGGGCA
TCGGCGCCGCGATGATCGCCTGGTGGGGCACGGCGATGCTCTGTTACGTCACGCCCAAGGAGCACCTGGGGCTGCCGAAC
CGGGACGACGTGAAGACCGGCGTCATCACGTACAAGATCGCCGCCCACGCGGCCGACCTGGCCAAGGGGCACCCGGGCGC
CCAGGAATGGGACGACGCCCTCTCCGACGCGCGGTTCGAGTTCCGCTGGGAGGACCAGTTCAACCTGGCCCTGGACCCGG
ACACGGCCCGGGAGTTCCACGACGAGACGCTGCCCGCCGAACCGGCGAAGACGGCGCACTTCTGCTCGATGTGCGGGCCG
AAGTTCTGCTCGATGAAGATCTCCCAGGACATCCGGCGCCAGCACGGCGGCTCGCGGGAGGAGATCGAGGAGGGCATGGC
CGAGAAGTCGAAGGAGTTCGCGGCCGCCGGCAACCGGGTCTACCTGCCCATCGCCGACTGA

Protein sequence :
MTTADARTPASKQNDGTPDGTTPDAGTPNDGAGKSIGWHKGYVQGSRPDLRVPVRQVHLTNGKHVTLYDTSGPYTDASVD
TDVRRGLAPLRENWIIARGDTEEYAGRPVRPEDDGLKHTSPRGGLRNLDAVFPGRPRQPRRSRDGRPVTQLAYARRGEVT
PEMEYVAIRENVEAEVVREEIAAGRAVLPANVNHPEIEPMIIGKRFLVKVNANIGNSAVTSSIEEEVDKMTWATQWGADT
VMDLSTGRNIHTTREWVLRNSPVPIGTVPLYQALEKVDGRAEELTWEIYKDTVIEQAEQGVDYMTVHAGVRLPYVPLTAR
RKTGIVSRGGSIMAAWCLAHHKESFLYEHFEELCEILATYDVTYSLGDGLRPGSIADANDEAQFAELRTLGELNTVAKRF
GVQTMIEGPGHVPMHKIKENIDLQQEICEEAPFYTLGPLTTDVAPAYDHITSGIGAAMIAWWGTAMLCYVTPKEHLGLPN
RDDVKTGVITYKIAAHAADLAKGHPGAQEWDDALSDARFEFRWEDQFNLALDPDTAREFHDETLPAEPAKTAHFCSMCGP
KFCSMKISQDIRRQHGGSREEIEEGMAEKSKEFAAAGNRVYLPIAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-174 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-174 63