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Name : nhaA (SGR_3327) Accession : YP_001824839.1 Strain : Streptomyces griseus NBRC 13350 Genome accession: NC_010572 Putative virulence/resistance : Unknown Product : pH-dependent sodium/proton antiporter Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG3004 EC number : - Position : 3908977 - 3910398 bp Length : 1422 bp Strand : + Note : exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH DNA sequence : GTGGCACCGCCCAATCCGCCCACCCCCGCGCCCCCGGCGCCGCCCCGGCGCCCGCTGCTCGGCAGGCTCTCGCTGCCCGA GCGGAACTACGTGGCGGAGGCGCTGCGCACCGAGACGGTCGGCGGTGTGCTGCTGCTGGTGGCGGCGGTCGCCGCGCTCG TCTGGGCGAACACCTTCGGCGGCTCGTACGACGAGGTCAGCGGCTTCCACTTCGGGCCCGGCTCCCTCGGCCTGGATCTC TCCGTGGCGCACTGGGCGGCGGACGGACTGCTCGCCGTCTTCTTCTTCGTCGCCGGCGTCGAGCTCAAGCGCGAACTGGT CGCGGGCGAGCTCCGCGACCCGAAGGCCGCCGCCCTCCCGGTGGTGGCGGCGCTGTGCGGCATGGCGGTGCCCGCCCTCG TCTACTTCCTCACCACGGCCGTCGGCGGCGGCTCGTCGGCCGGCTGGGCGGTCCCCACCGCCACCGACATCGCCTTCGCC CTCGCCGTCCTCGCGGTGATCGGCACCTCGCTGCCGTCCGCGCTACGGGCCTTCCTGCTCACGCTGGCCGTCGTCGACGA CCTCTTCGCGATCCTGATCATCGCGGTGTTCTTCACCTCGGACCTGAACTTCCTGGCGCTCGGCGGGGCCGTTCTCGGCC TGGTCGTCTTCCATCTCCTCCTGCGCTTCGACGTCCGGGGCTGGTACGTCTACGTTCCGCTCGCCCTGGTCATCTGGGGC CTGATGTACAACAGCGGCGTGCACGCCACCATCGCCGGTGTCGCCATGGGCCTGATGCTGCGCTGCACCCGTCGCGAGGG CGAGGAGCACTCCCCCGGCGAGCACATCGAACACCTGGTCCGCCCGCTCTCCGCCGGGATCGCCGTGCCGCTGTTCGCCC TGTTCTCCGCCGGGGTCGCGCTGAACGGCGAGGCGCTGGCCGGCGTCTTCACCCGGCCCGAGACGCTCGGCGTCGTCCTC GGTCTCGTCGTCGGCAAGACCGTGGGCATCTTCGGCGGCACCTACCTCGCCGCCCGCTTCACCAGGGCGGAGCTGAACAA GGACCTGGCCTGGGCCGATGTCTTCGCGGTCGCCTCGCTCGCCGGCATCGGGTTCACCGTCTCGCTGCTCATCGGCGAGC TCGCCTTCGAGGGCGACCCGGAGATGGTCAACGAGATCAAGGCCGCCGTCCTGATCGGATCGCTGACCGCGGCCCTGCTC GCCTGCGTGCTGCTCAAGATCCGGGTACGCAAGTACCGGGCGCTGGTCACGGCCGAGGAGCTGGACGAGGACGAATCCGG GGTACCCGACGTCTACGAGCAGGATGATCCCGAATATCACCTGCGGATGGCCGCCCTCCACGAGCGGAAGGCGGCGGAAC ACCGCCGTCTCGCCGAAGAACGGGCGGGGGCAGCGCGCAACAAGCCGAACAGTCCGGCATGA Protein sequence : MAPPNPPTPAPPAPPRRPLLGRLSLPERNYVAEALRTETVGGVLLLVAAVAALVWANTFGGSYDEVSGFHFGPGSLGLDL SVAHWAADGLLAVFFFVAGVELKRELVAGELRDPKAAALPVVAALCGMAVPALVYFLTTAVGGGSSAGWAVPTATDIAFA LAVLAVIGTSLPSALRAFLLTLAVVDDLFAILIIAVFFTSDLNFLALGGAVLGLVVFHLLLRFDVRGWYVYVPLALVIWG LMYNSGVHATIAGVAMGLMLRCTRREGEEHSPGEHIEHLVRPLSAGIAVPLFALFSAGVALNGEALAGVFTRPETLGVVL GLVVGKTVGIFGGTYLAARFTRAELNKDLAWADVFAVASLAGIGFTVSLLIGELAFEGDPEMVNEIKAAVLIGSLTAALL ACVLLKIRVRKYRALVTAEELDEDESGVPDVYEQDDPEYHLRMAALHERKAAEHRRLAEERAGAARNKPNSPA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| nhaA1 | YP_001220808.1 | NahA family Na(+)/H(+) antiporter | Not tested | chp/tomA region | Protein | 4e-55 | 50 |
