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Name : guaA (SGR_2745) Accession : YP_001824257.1 Strain : Streptomyces griseus NBRC 13350 Genome accession: NC_010572 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 3247328 - 3248914 bp Length : 1587 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : GTGCCAGCAGCACCCCCCGCCGCCCCCGACGCCACGGCCGACGTGGTCCTCGTCGTCGACTTCGGCGCGCAGTACGCCCA GCTCATCGCCCGCCGAGTCCGTGAGGCCCGGGTCTACAGCGAGATCGTCCCGTCCACCATGCCGGTGGCCGAGATGCTGG CGAAGAACCCGCGCGCGATCATCCTCTCCGGCGGCCCCTCGTCGGTGTACGCGGAGGGCGCGCCGTCCCTGGACCGCGCG ATCTTCGAGGCCGGGGTGCCGGTCTTCGGCATGTGCTACGGCTTCCAGCTGATGGCCACCGCGCTCGGCGGCACGGTCGA CGACAACGGGGCCCGCGAGTACGGCCGTACCCCCCTGCACGTCACCAAGGCGGGCTCGACCCTCTTCGAGGGCACGCCCA CCGAGCAGCCGGTGTGGATGTCGCACGGCGACGCCTGCTCGGCGGCCCCCGAGGGCTTCGCCGTCACCGCGTCCACCGAC GTGGTCCCGGTCGCCGCCTTCGAGAACGACGAGAAGAAGCTCTACGGCGTCCAGTACCACCCGGAGGTCATGCACTCCAC CCACGGCCAGCAGGTCCTGGAGCACTTCCTCTACCGCGGCGCGGGCATCGAGCCGAACTGGACCACCACCAACGTGGTCG AGGAGCAGATCGCCCTCATCCGCGAGCAGGTCGGCGACAAGCGCGCCATCTGCGGCCTCTCCGGCGGTGTGGACTCCGCG GTCGCCGCGGCCCTCGTCCAGAAGGCCATCGGCTCCCAGCTCACCTGCGTGTACGTGGACCACGGCCTCATGCGCAAGGG CGAGACCGAGCAGGTCGAGAAGGACTTCGTCGCCGCGACCGGCGCGAAGCTCAAGGTGGTCGACGCGGAGAAGCGCTTCC TCGACGCCCTGGCCGGTGTGTCCGACCCGGAGCAGAAGCGGAAGATCATCGGCCGCGAGTTCATCCGCGTCTTCGAGCAG GCCCAGCTGGAGATCCTCCAGGAGGAGGGCCCCGAGGTCGCCTTCCTCGTCCAGGGCACGCTCTACCCCGACGTGGTCGA GTCCGGCGGCGGCACCGGCACCGCCAACATCAAGTCCCACCACAACGTCGGCGGCCTCCCCGACGACATCGAGTTCGAGC TCGTCGAGCCGCTGCGCCAGCTGTTCAAGGACGAGGTCCGGATGGTCGGCCAGGAGCTGGGCCTCCCCGACGAGATCGTC CAGCGCCAGCCGTTCCCCGGCCCCGGCCTCGGCATCCGCATCGTCGGCGAGGTCACCAAGGAGCGCCTGGACCTGCTCCG CGACGCCGACGCCATCGCCCGTGAGGAGCTGACGGCGGCCGGGCTGGACCGCGACATCTGGCAGTGCCCCGTGGTCCTCC TCGCCGACGTCCGCTCGGTCGGCGTGCAGGGCGACGGCCGCACCTACGGTCACCCGATCGTGCTGCGCCCGGTCTCCTCC GAGGACGCCATGACGGCCGACTGGTCGCGCCTGCCGTACGAGACGCTGGCGAAGATCTCCACCCGCATCACCAACGAGGT CGCCGAGGTCAACCGCGTCGTCCTCGACGTGACGAGCAAGCCGCCGGGGACCATCGAGTGGGAGTGA Protein sequence : MPAAPPAAPDATADVVLVVDFGAQYAQLIARRVREARVYSEIVPSTMPVAEMLAKNPRAIILSGGPSSVYAEGAPSLDRA IFEAGVPVFGMCYGFQLMATALGGTVDDNGAREYGRTPLHVTKAGSTLFEGTPTEQPVWMSHGDACSAAPEGFAVTASTD VVPVAAFENDEKKLYGVQYHPEVMHSTHGQQVLEHFLYRGAGIEPNWTTTNVVEEQIALIREQVGDKRAICGLSGGVDSA VAAALVQKAIGSQLTCVYVDHGLMRKGETEQVEKDFVAATGAKLKVVDAEKRFLDALAGVSDPEQKRKIIGREFIRVFEQ AQLEILQEEGPEVAFLVQGTLYPDVVESGGGTGTANIKSHHNVGGLPDDIEFELVEPLRQLFKDEVRMVGQELGLPDEIV QRQPFPGPGLGIRIVGEVTKERLDLLRDADAIAREELTAAGLDRDIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSS EDAMTADWSRLPYETLAKISTRITNEVAEVNRVVLDVTSKPPGTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-180 | 73 |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 8e-135 | 52 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 6e-135 | 52 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 5e-135 | 52 |
