Gene Information

Name : SGR_2579 (SGR_2579)
Accession : YP_001824091.1
Strain : Streptomyces griseus NBRC 13350
Genome accession: NC_010572
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 3040017 - 3041162 bp
Length : 1146 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
ATGAGCGACCAGCACAGCTTCGAAACCCTCGCCATCCACGCGGGGAACACCGCCGACCCCCTCACCGGCGCGGTGGTTCC
GCCGATCTACCAGGTCTCCACGTACAAGCAGGACGGCGTGGGCGGACTGCGCGGCGGCTACGAGTACAGCCGCAGCGCCA
ACCCGACCCGCACCGCCCTGGAGGAGAACCTCGCGGCCCTCGAAGGCGGCCGCCGCGGTCTCGCCTTCGCCTCCGGTCTC
GCCGCCGAGGACTGCCTCCTGCGGACGCTGCTGACCCCCGGCGACCACGTGGTCATCCCGAACGACGCATACGGCGGCAC
GTTCCGGCTGTTCGCGAAGGTCGCCTCGCGGTGGGGCGTGGAGTTCTCCGTGGCCGACACCTCGGACGTGGCCGCCGTAC
GGGCCGCGATCACCCCGCGCACCAAGGCGGTCTGGGTGGAGACCCCGTCCAACCCGCTGCTCGGCATCACCGACATCGCC
GCCGTCGCCCAGGTCGCGCACGACGCCGGGGCCCGCCTCGTCGTCGACAACACCTTCGCCTCGCCCTACCTCCAGCAGCC
CCTCGCGCTCGGCGCCGACGTCGTCGTGCACTCCACCACCAAGTACATGGGCGGCCACTCCGACGTCGTCGGGGGCGCGC
TCGTCGTCAGCGACCCGGAACTCGCCGAGGAACTGGCGTACCACCAGAACGCCATGGGCGCGGTCGCCGGACCCTTCGAC
GCCTGGCTCGTGCTGCGCGGCATCAAGACCCTCGCCGTCCGCATGGACCGGCACACCGAGAACGCCACCAAGGTCGCCGA
CCTGCTGACCCGGCACCCCAAGGTCTCCCAGGTCCTCTACCCGGGCCTGCCCGAGCACCCCGGCCACGAGGTCGCCGCCA
AGCAGATGAAGGCCTTCGGCGGCATGGTGTCGTTCCGCGTCGCGGGCGGCGAGGAGGCGGCGGTCGAGGTCTGCAACCGG
GCGAAGCTGTTCACGCTCGGCGAGTCCCTCGGCGGGGTCGAGTCCCTCCTGGAGCACCCGGGCCGGATGACGCACGCCTC
CGCCGCCGGCTCCCCGCTGGAGGTCCCGGCCGACCTGGTCCGGCTCTCCGTCGGCATCGAGAACGGCGACGACCTGCTCG
CCGACCTCGCCCAGGCGCTCGGCTGA

Protein sequence :
MSDQHSFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGVGGLRGGYEYSRSANPTRTALEENLAALEGGRRGLAFASGL
AAEDCLLRTLLTPGDHVVIPNDAYGGTFRLFAKVASRWGVEFSVADTSDVAAVRAAITPRTKAVWVETPSNPLLGITDIA
AVAQVAHDAGARLVVDNTFASPYLQQPLALGADVVVHSTTKYMGGHSDVVGGALVVSDPELAEELAYHQNAMGAVAGPFD
AWLVLRGIKTLAVRMDRHTENATKVADLLTRHPKVSQVLYPGLPEHPGHEVAAKQMKAFGGMVSFRVAGGEEAAVEVCNR
AKLFTLGESLGGVESLLEHPGRMTHASAAGSPLEVPADLVRLSVGIENGDDLLADLAQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-68 48
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-69 48
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-52 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SGR_2579 YP_001824091.1 cystathionine gamma-synthase BAC0207 Protein 3e-56 44