Gene Information

Name : Exig_2634 (Exig_2634)
Accession : YP_001815099.1
Strain : Exiguobacterium sibiricum 255-15
Genome accession: NC_010556
Putative virulence/resistance : Virulence
Product : polysaccharide biosynthesis protein CapD
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 2613131 - 2614981 bp
Length : 1851 bp
Strand : -
Note : PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: bce:BC5274 UDP-N-ac

DNA sequence :
ATGAAACTTTATTATTATTATCGTACTCTGACGCTCGCCTGTATTGATGCGGCAGCATTAGTTATTGCTATGAGTTTTAC
GTACTTTTTCTTATATCCAAAAGAATTATTTAAATTAATTGATAGTCAACTATTACTTCAATCTGCAGGTGTCTTTGCAC
TATTATTCGTGACACTTGCTTTTTTGATGAAACTTTATCGAGTCAATTGGAAGTATGCAAGTGTTCAAGAAGCCATGACA
TTATCCTTATCTCTAGGCCTAAGTTCAATTGGATTGATGGTTTACCAAAATATTATTTTTAATGAAGTACTAGAGCGAAT
CACAATTCTTAGTTTTTGTATTGCTTTATTATTACTCGGTGCAATTCGTGTTGCTTTACGATTACTCGGTATTGGACAAC
ATTTACGTAAATATGCGCTACCGAGAAGAATGGTCAAATCACGTAAACGGACACTTGTAATCGGAGCAGGGCGCGCTGGT
CGTTCTTTAGTCCGACAGCTTTACGTATCTCCTTTTCATGAGTTAAAACCGGTAGCTTTTCTAGACGATGATCCAAAAAA
TATGCACTTTATGATTCAGGGAATTGAAGTTGTCGGAACGACTGAAGATTTAAAAGCAGTCATCGAAAAGCACCGAATTG
AAGCGATTGTTTTAGCGATTCCTTCACTAACACAACAACGGCGGATTGAGCTGATTACAGAAGCCAAAACACTTTGTAAA
AACGTTCAGACATTGCCGATGATTGAAGAATTAATTACCGGTAAAATTTCAGTCAGTGCAATCCGTGATGTGTCGATTGA
GGATTTGCTTGGTCGTGAACCGGTTGAACTAGATATTTCCGGAATTAAATCGGAAATTGAGGGACGAACAGTCCTTGTAA
CCGGAGCCGGTGGGTCGATTGGATCAGAAATTTGCCGACAAATCATTCAATTTAATCCAACTACGCTTGTGTTACTTGGT
CATGGTGAAAACAGTATTTACTTGATTGAACGTGAACTACGTGGACTTCAGTTTCCGATTAATTTGGTGTCGATTATTGC
AGATGTCCAGGATCGCACTCGACTAGAAGAAGTATTTGCGACACATAAACCGCAAGTTGTGTTCCATGCAGCTGCACACA
AGCATGTCCCTTTAATGGAAGCAAACCCATATGAATCGGTTAAAAACAATGTCTATGGAACAAAAAATGTCGCAGAAGTA
GCTGATTTGTTTAACGTTGAACGCTTTGTGATGATTTCAACGGATAAGGCAGTAAATCCAACGAATGTCATGGGATCCAC
AAAACGCATCGCAGAGATGGTCATTCAAGATTTAGGACGTCGTAGTAAAACAAAATTTGCAGTTGTACGTTTTGGAAACG
TGCTGGGAAGTCGTGGTTCTGTCATTCCACTCTTTAAGTCGCAGATTTTAGCTGGTGGACCAGTTACGGTGACCCATCCA
GAAATGACACGTTTCTTTATGACAATTCCCGAAGCAAGTCGTTTGGTCATTCAAGCGGGGATTTTAGCTGATGGTGGAGA
AGTGTTTGTCCTTGATATGGGAGAACCGGTTAAGATTGTTGACCTTGCGAAGAACATGATTGAACTGAGTGGATTTACGG
AAGATGAAATGCCAATCGTATTCTCAGGGATTCGACCGGGAGAAAAGATGTATGAAGAACTGCTGAAAGACGGTGAAGTT
GACCCGGAAGCGATCTATCCGAAAATCTTTGTTGGCAGAACACGCCAAAAAGAATCACTCGAGCACATCTTTGCACTCGT
AAACCAACACAGAGAGTCACCATTACAATTACGCAATGTTTTACTTGATATTGCTAACGATGTCAGTACGCTTGAAAAGA
ATTTTATTTAA

Protein sequence :
MKLYYYYRTLTLACIDAAALVIAMSFTYFFLYPKELFKLIDSQLLLQSAGVFALLFVTLAFLMKLYRVNWKYASVQEAMT
LSLSLGLSSIGLMVYQNIIFNEVLERITILSFCIALLLLGAIRVALRLLGIGQHLRKYALPRRMVKSRKRTLVIGAGRAG
RSLVRQLYVSPFHELKPVAFLDDDPKNMHFMIQGIEVVGTTEDLKAVIEKHRIEAIVLAIPSLTQQRRIELITEAKTLCK
NVQTLPMIEELITGKISVSAIRDVSIEDLLGREPVELDISGIKSEIEGRTVLVTGAGGSIGSEICRQIIQFNPTTLVLLG
HGENSIYLIERELRGLQFPINLVSIIADVQDRTRLEEVFATHKPQVVFHAAAHKHVPLMEANPYESVKNNVYGTKNVAEV
ADLFNVERFVMISTDKAVNPTNVMGSTKRIAEMVIQDLGRRSKTKFAVVRFGNVLGSRGSVIPLFKSQILAGGPVTVTHP
EMTRFFMTIPEASRLVIQAGILADGGEVFVLDMGEPVKIVDLAKNMIELSGFTEDEMPIVFSGIRPGEKMYEELLKDGEV
DPEAIYPKIFVGRTRQKESLEHIFALVNQHRESPLQLRNVLLDIANDVSTLEKNFI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 4e-111 53
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 1e-115 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Exig_2634 YP_001815099.1 polysaccharide biosynthesis protein CapD VFG1300 Protein 4e-113 50
Exig_2634 YP_001815099.1 polysaccharide biosynthesis protein CapD VFG0029 Protein 1e-79 44