Gene Information

Name : Exig_2569 (Exig_2569)
Accession : YP_001815035.1
Strain : Exiguobacterium sibiricum 255-15
Genome accession: NC_010556
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2543180 - 2544523 bp
Length : 1344 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: sat:SYN_01113 UDP-N-acetyl-D-galactosamine 6-dehydrogenase

DNA sequence :
ATGAACAAGGCAGTCAAACACATCGTAGATACGACAGCAGCCCAAACACGATCACTCCCCATCGCCAACCGTTCGATTGC
CGTCGTCGGTCTAGGATATGTCGGGCTTCCCGTCGCTGTCGCCTTTGGTGAAAAAACGGAAGTCGTCGGCTTTGACATCA
AAGAACAGCGGGTTGCCGAACTGAAAGAGGGCATCGATGCGACGCTTGAACTTAGTCCATTCGTTCTTAAGAATGCCGAC
GTCGAATACGTCACCGACGCAGCGGCACTCGGAGCAAGCGACTTCATCATCATCGCTGTTCCGACACCGATCAATGCGCA
AAATCAGCCGGATTTGACGCCGCTCCTCCGTGCGTCGCAACTCGTCGGACGCCAGTTGAACAAAGGGGATATCGTCGTCT
ACGAGTCGACGGTCTACCCGGGAGCGACGGAGGAAGATTGTATCCCGGTCCTCGAAGAAGCATCGGGTCTGCAGGCCGGG
GTCGACTTCTTCGTCGGCTACTCGCCGGAACGGATCAATCCCGGCGATCATGAGCATACATTTAAAACGATCAAAAAAAT
CGTCTCGGCCCAAAATCAAGAAACACTTGATATCGTCGCTGAAGTCTACGAAGCGGTCGTCGAAGCCGGCGTCCACCGGG
CATCTTCGATCAAAGTCGCCGAAGCCGCTAAAATCATCGAGAATACACAACGCGACCTGAACATCGCCTTGATGAACGAA
CTGGCGATCATCTTCGACCGGATGAACATCGATACGCTCGAGGTCCTCGAGGCTGCCGGAACAAAATGGAACTTCTTACC
GTTCCGTCCGGGACTCGTCGGTGGTCATTGCATCGGTGTCGACCCGTTCTACTTGACGATGAAGGCAGAATCACTCGGTT
ATCATCCGGAAGTCATCCTCGCCGGACGGCGGATCAACGACACGATGGGACGGTTCATCGCCACGTCGCTCGTCAAGAAT
CTGATTAAACAAAACATGCCGGTTCTTGGTGCACGAGTGACGGTGCTTGGTCTGTCATTCAAGGAAAACGTCAGCGATAT
CCGGAACTCGAAAGTTGCGAACCTCGTCAAGGAAATCGAAGAGTTCGGAATTGAAGTCCAGGTGACGGATCGTCTCGTCG
AAAAAGGGGACGCGAAACGCGAGTACGGCATCGATTTAGTCGATTTAGCAGACTTAAAACCAGCCGATGTCGTCATCTTC
GCCGTCTCGCATGAAGAGTACGTCGAAGGCAACTGGCTGCTTGCGCAACACCTGCTCAAAGTCGGTCGCGGCATCGTCAT
CGATATCAAAGGGATGTTGACGCCGTCAGAAAAACCGGAAGGGGTGCATTTATGGCGACTTTAA

Protein sequence :
MNKAVKHIVDTTAAQTRSLPIANRSIAVVGLGYVGLPVAVAFGEKTEVVGFDIKEQRVAELKEGIDATLELSPFVLKNAD
VEYVTDAAALGASDFIIIAVPTPINAQNQPDLTPLLRASQLVGRQLNKGDIVVYESTVYPGATEEDCIPVLEEASGLQAG
VDFFVGYSPERINPGDHEHTFKTIKKIVSAQNQETLDIVAEVYEAVVEAGVHRASSIKVAEAAKIIENTQRDLNIALMNE
LAIIFDRMNIDTLEVLEAAGTKWNFLPFRPGLVGGHCIGVDPFYLTMKAESLGYHPEVILAGRRINDTMGRFIATSLVKN
LIKQNMPVLGARVTVLGLSFKENVSDIRNSKVANLVKEIEEFGIEVQVTDRLVEKGDAKREYGIDLVDLADLKPADVVIF
AVSHEEYVEGNWLLAQHLLKVGRGIVIDIKGMLTPSEKPEGVHLWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-124 62
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-101 54
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 3e-101 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Exig_2569 YP_001815035.1 nucleotide sugar dehydrogenase VFG0431 Protein 1e-101 54