Gene Information

Name : Exig_2343 (Exig_2343)
Accession : YP_001814810.1
Strain : Exiguobacterium sibiricum 255-15
Genome accession: NC_010556
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2309428 - 2310594 bp
Length : 1167 bp
Strand : -
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGCGTAAAAAGACAGCATTGATTCATGGAGGAACAGGCGTCGATCGAGCAACAGGTGCCGTTACACCCCCGATTTATCA
AACAAGCACATACAAACAGGAAAAAATCGGTCAGTTAAAAGAAGGATATGAGTATTCCCGGACAGCGAACCCGACACGGA
CGAGCATCGAACGTCTGATTGCCGATCTTGAAGGCGGTGCACGCGGTTTTGCCTTCGGATCAGGGATGGCAGCGATTCAC
GCTGTCTTTAACCTGCTCGAATCAGGCGACCACATCGTCATGACAGATGACGTCTACGGCGGGACATTCCGTTTGATGCA
GCGTGTCTTACCGAAGTTCAACATCCAAGTGACGTTCGTCGATACGACGGATCTCGCGGCGACGGAAGCTGCGGTGCAAG
ACAACACGAAGATGCTGTATGTCGAAACACCGACGAACCCATTGTTGAAAGTTACAGATATCGCAGCAGTTGCTGAGATC
GCGAAACGCAACAACTTGAAACTCGTCGTCGATAACACATTCGCGACACCGTACTTGCAACAACCACTCGCTCTCGGCGC
AGATATCGTCTTGCACAGCGCGACAAAATACATCGGCGGTCATTCGGACGTCGTCGCCGGACTTGTCGTTGTCAACAGCG
ACGAGCTCGGAGAAGATCTTCACTTCATCCAAAACTCGACCGGCGGTATTCTTGGACCGCAGGACAGCTTCCTGCTCGTC
CGTGGATTACGGACACTTGGTATCCGGATGGATGCAATCGAAGAAACATCACACGATCTCGTTCACTTCTTACAGGAACA
GGACGTCGTTTCAAACATCTTCTATCCGGGACTTCCAACACATCCGGGTCACGCGACACAACAGAAACAGGCGACCGGTT
TCGGCGGAATGATCAGTTTTGATGTCGGTTCAGCAGAAAATGCGGAGAAACTCGTCGAAGCGACACATTTCTTCACATTG
GCTGAAAGTCTTGGAGCGGTCGAGAGTTTGATTTCCGTTCCGGCACGGATGACGCATGCGTCGATTCCAGCAGAGCGTCG
CGCAGAACTCGGAATTACAGATGGTCTCGTTCGGATCTCGGTCGGTCTTGAGGACGCGGAAGACTTGAAAGAAGATTTGG
CACGTGCTTTCAGTCTGCTTCAACCGGTTTCAGAAAAAACTGTTTGA

Protein sequence :
MRKKTALIHGGTGVDRATGAVTPPIYQTSTYKQEKIGQLKEGYEYSRTANPTRTSIERLIADLEGGARGFAFGSGMAAIH
AVFNLLESGDHIVMTDDVYGGTFRLMQRVLPKFNIQVTFVDTTDLAATEAAVQDNTKMLYVETPTNPLLKVTDIAAVAEI
AKRNNLKLVVDNTFATPYLQQPLALGADIVLHSATKYIGGHSDVVAGLVVVNSDELGEDLHFIQNSTGGILGPQDSFLLV
RGLRTLGIRMDAIEETSHDLVHFLQEQDVVSNIFYPGLPTHPGHATQQKQATGFGGMISFDVGSAENAEKLVEATHFFTL
AESLGAVESLISVPARMTHASIPAERRAELGITDGLVRISVGLEDAEDLKEDLARAFSLLQPVSEKTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-111 61
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-112 61
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-74 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Exig_2343 YP_001814810.1 cystathionine beta-lyase BAC0207 Protein 1e-66 42