Gene Information

Name : leuS (Exig_2275)
Accession : YP_001814744.1
Strain : Exiguobacterium sibiricum 255-15
Genome accession: NC_010556
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 2242187 - 2244592 bp
Length : 2406 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCCGTACAATCATCGTGAAATCGAACCGAAATGGCAAGCGCGTTGGGAACAGGACAATGCGTTCGTCACAACAGAAGA
TCCGGAAAAAGAAGGCTTTTATGCGTTAGACATGTTTCCTTATCCATCGGGAGCAGGACTTCATGTCGGTCACCCGGAAG
GATACACGGCAACCGATATCCTGGCCCGGATGAAACGGATGCAAGGATACAACGTCCTTCACCCGATGGGATGGGATGCG
TTTGGACTTCCGGCGGAGCAGTATGCGCTTGATACAGGAAATGACCCGCGGGAGTTCACTGCCCAAAACATCGAAACCTT
TAAACGTCAGTTAAAAGACTTGGGATTCTCGTACGACTGGGATCGTGAAATCAATACGACGGATCCGAAATATTACAAAT
GGACACAGTGGATTTTTACGAAATTGTATGAACAGGGACTCGCTTTCGTTGACGAAGTCGCCGTTAACTGGTGCCCGGCT
CTTGGAACGGTGCTTGCGAACGAGGAAGTCATCGACGGGCTGTCCGAGCGTGGTAATCATCCGGTTGTCCGCGTCCCGAT
GCGGCAGTGGGTTTTAAAAATTACCGAGTACGCGGACCGTTTGCTCGAAGATTTGGATGAACTCGACTGGCCGGAATCCG
TCAAGGAAATGCAACGGAACTGGATCGGAAAATCGGAAGGTGCGGAAATCGACTTTACGATCGACGGTCATAAAAAACAA
GTAACGGTCTTCACGACACGTCCGGATACCGTCTTCGGCGCAACGTATCTCGTTCTGGCACCGGAGCATCCATTTGTCAC
GGATATCACAACAGAGGATCACGAAGAAGCGGTTAAAGCATACATCGCGTCTGTCCAGACGAAGTCAGATTTGGAACGGA
CGGATCTTGCGAAAGAAAAAACAGGCGTCTTCACGGGAGCTTTTGCCGTCAACCCGATTTCAGGCGAACGTCTGCCAATC
TGGATCGCCGATTATGTCCTCGCGACATACGGAACAGGCGCGATCATGGCCGTTCCGGCACACGATGAGCGTGATCATGA
ATTTGCGAAACAGTTTGACCTTCCGATCATCGAAGTCGTCAAAGGCGGTAACGTTGACGAAGTAGCGTATACGGGTGAAG
GCGAACACGTCAATTCACAAATGCTCGACGGATTGTCAAAACAGGAGGCGATTGAAACGATCATCGCTGAACTGGAGACG
AATCAAGTCGGACGCAAAAAAATCACGTTCCGATTGCGTGACTGGTTATTCAGCCGTCAGCGCTACTGGGGTGAACCGAT
TCCGGTCGTCCACATGGAAGACGGAACGATGAAGACACTCGATAAATCGGAACTTCCGCTTGAATTGCCGATGATTCCGG
AAATCAAGCCGTCCGGCACAGGTGAATCACCACTCGCCCTTGCAGAAGACTGGCTCGATTACACGGATCCGGTCACGGGA
CTTAAAGGACGCCGCGAGACGAATACGATGCCACAATGGGGCGGCAGCTGCTGGTACTACCTCCGCTTCATTGATCCGCA
TAATGAAGAGGCGATTGCCGATCCGGAAAAACTAAAATACTGGCTTCCGGTCGATATTTATATCGGAGGAGCCGAGCATG
CCGTGCTTCATTTACTGTATGCCCGCTTCTGGCATAAAGTCTTGTATGATATCGGTGTCGTACCGACGAAAGAACCATTC
CAAAAGTTGTATAACCAAGGGATGATTCTTGGAGAAAACAATGAAAAAATGTCGAAATCACGCGGAAACGTCATCAATCC
GGATGAAATCGTCAAATCGCACGGTGCAGATACACTCCGCTTGTACGAAATGTTCATGGGACCGCTTGATGCTTCGGTGT
CGTGGTCGGAGAACGGTCTTGACGGGGCACGTCGTTTCCTTGACCGCGTCTGGCGTCTGTTCGAACGGACAGCGGACATT
CAGGACGTGACGACAGTCGATGCAGACTTTGAACGTGTCTACCATCAGACGGTTAAAAAGGTAACGGAAGACTTCACGAA
CATTCAGTTCAACACCGGGATTTCGCAGTTGATGGTCTTCGTCAACGAGGCCAATAAACAACCGGTCTTACCGCGTCACT
TCCTTCGAGGATTCATTCAATTGCTGACCCCGGTCGCACCGCACCTTGGGGAAGAGTTATGGGAACAGCTTGGTTTTGAG
GATACATTGACATATGCGGCATGGCCGACATTTGACGAAACGAAACTCGTCAGCGATACAATGGAATTCGTCATTCAAGT
CAACGGTAAAGTCCGTTCGAAGCTCGTCATCAGCATGGAGGCAACAAAAGAAGAAATTGAAGCCCTTGCGTTTGCCGATG
AAAAAACACAAGAGTGGATTGGCGATAAAACGGTTCGGAAAGTCATCGTCGTTCCGAAAAAACTGATCAATATCGTAGCG
AACTAA

Protein sequence :
MPYNHREIEPKWQARWEQDNAFVTTEDPEKEGFYALDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLHPMGWDA
FGLPAEQYALDTGNDPREFTAQNIETFKRQLKDLGFSYDWDREINTTDPKYYKWTQWIFTKLYEQGLAFVDEVAVNWCPA
LGTVLANEEVIDGLSERGNHPVVRVPMRQWVLKITEYADRLLEDLDELDWPESVKEMQRNWIGKSEGAEIDFTIDGHKKQ
VTVFTTRPDTVFGATYLVLAPEHPFVTDITTEDHEEAVKAYIASVQTKSDLERTDLAKEKTGVFTGAFAVNPISGERLPI
WIADYVLATYGTGAIMAVPAHDERDHEFAKQFDLPIIEVVKGGNVDEVAYTGEGEHVNSQMLDGLSKQEAIETIIAELET
NQVGRKKITFRLRDWLFSRQRYWGEPIPVVHMEDGTMKTLDKSELPLELPMIPEIKPSGTGESPLALAEDWLDYTDPVTG
LKGRRETNTMPQWGGSCWYYLRFIDPHNEEAIADPEKLKYWLPVDIYIGGAEHAVLHLLYARFWHKVLYDIGVVPTKEPF
QKLYNQGMILGENNEKMSKSRGNVINPDEIVKSHGADTLRLYEMFMGPLDASVSWSENGLDGARRFLDRVWRLFERTADI
QDVTTVDADFERVYHQTVKKVTEDFTNIQFNTGISQLMVFVNEANKQPVLPRHFLRGFIQLLTPVAPHLGEELWEQLGFE
DTLTYAAWPTFDETKLVSDTMEFVIQVNGKVRSKLVISMEATKEEIEALAFADEKTQEWIGDKTVRKVIVVPKKLINIVA
N

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 63