Gene Information

Name : serS (PMI0700)
Accession : YP_002150467.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 764633 - 765922 bp
Length : 1290 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATCCAAATCTACTGCGTAATGAGCTAGACGCGGTCGCCGAAAAACTGGCTCGCAGGGGGTTTACCCTCGATGT
GGAAAAAATTCGTCAACAAGAAGAACGCCGTAAGGTGTTACAGGTTGAAACAGAATCCCTGCAAGCAGAACGTAATTCCC
GATCGAAGTCTATTGGTGCTGCTAAAGCGCGTGGTGAAGATATTGAGCCACTTCGTCAGGAAGTTAACCAATTAGGTGAA
AAACTTGAAGCGGCAAAAGCGGAATTAGATAAACTGCAAGCCGACATTCGTGACTATGCGTTAACTTTACCGAATCTGCC
TCATGACTCTGTGCCTAATGGTAAAGATGACAGCGAGAACGTTGAAGTATTTCGTTGGGGTGAACCAAAGACTTATGACT
TTGAATTAAAAGATCACGTTACTCTAGGTGAACTTACAGATGGTTTAGATTTCCCATCTGCCGTGAAAATCACCGGTTCA
CGTTTTGTTGTGATGAAAGGTCAAATTGCACGTTTACATCGCGCGATCGCCCAGTTCATGCTGAACTTGCATACAGAACA
ACATGGCTATCAAGAAATGTATGTGCCTTATTTAGTTAACCATGCCACTTTATATGGCACAGGACAGTTACCTAAATTCA
GTGGTGATTTATTCCATACCAAACCACTTGAAGAAGAGTCTGAAAGCCAATATGCGCTGATCCCAACAGCAGAAGTACCT
GTTACCAATATGGTTAGAGACGTTATTCTCGAAGAAGACGAACTACCATTGCGAATGACTGCACATACGCCATGTTTCCG
CTCAGAAGCGGGCTCTTATGGCCGTGATACACGTGGTCTGATCCGTATGCACCAATTTGATAAAGTAGAGTTAGTACAAA
TTGTACATCCTGAAAAATCAATGGATGCATTAGAAGAGCTAACTGGCCATGCAGAGAAAGTGTTGCAATTGCTCAATCTG
CCTTACCGTAAAGTGGTACTTTGTACAGGTGATATGGGCTTTGGTGCACGTAAAACCTATGACTTAGAAGTGTGGGTACC
GGCACAAAATACCTACCGTGAAATTTCTTCATGCTCTAACTGCTGGGATTTCCAAGCACGCCGTATGCAAGCACGTTTCC
GTGCTAAAGGTGACAAGAAAACTCAACTTGTGCACACTTTAAATGGTTCAGGTTTAGCTGTAGGGCGTACTTTAGTCGCC
ATTATGGAAAACTATCAAACCGCTGATGGTCGTATTGAAATTCCAGAAGTTTTACGTCCTTATATGAATGGCCTTGAGTA
TATTGGTTAA

Protein sequence :
MLDPNLLRNELDAVAEKLARRGFTLDVEKIRQQEERRKVLQVETESLQAERNSRSKSIGAAKARGEDIEPLRQEVNQLGE
KLEAAKAELDKLQADIRDYALTLPNLPHDSVPNGKDDSENVEVFRWGEPKTYDFELKDHVTLGELTDGLDFPSAVKITGS
RFVVMKGQIARLHRAIAQFMLNLHTEQHGYQEMYVPYLVNHATLYGTGQLPKFSGDLFHTKPLEEESESQYALIPTAEVP
VTNMVRDVILEEDELPLRMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQIVHPEKSMDALEELTGHAEKVLQLLNL
PYRKVVLCTGDMGFGARKTYDLEVWVPAQNTYREISSCSNCWDFQARRMQARFRAKGDKKTQLVHTLNGSGLAVGRTLVA
IMENYQTADGRIEIPEVLRPYMNGLEYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-97 55