Gene Information

Name : intB (PMI3468)
Accession : YP_002153152.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Unknown
Product : prophage integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 3798109 - 3799374 bp
Length : 1266 bp
Strand : +
Note : identical over its internal regions to the partial CDS PMI3494 and PMI3502

DNA sequence :
ATGGCTCTTACTGATGCTAAAGTCAGGGCTGCCAAGCCTCTGGATAAATCGTATAAATTGACCGATGGTGATGGTATGCA
CTTGATGGTACATACCAACGGCTCAAAATATTGGCGTTTACAGTATCGCTTTGGCGGTAAGCAAAAAATGTTAGCGCTGG
GTGTTTACCCGGATATTTCACTTGCAGAAGCCAGAGAGAAAAGAGATGCAGCCAGAAAGTTAATAGCGAATGGTTTTGAT
CCCAGTGAAAAACGGAAAGAAGTGAAAGAAGAGCAACAAAAGGAATTTAATACATTCGAGAAGGTTGCACGTGATTGGCA
TGCAACTAATCAGCGATGGTCAGAAGGGCATAGCCATCGAGTACTCAAAAGCCTTGAGGACAATATCTTTGTTGCTATTG
GTAAACGTAATATTGCTGAACTAAAAACTCGCGATCTACTCGAACCTATTAAAGCCGTAGAGATGTCTGGACGTCTTGAG
GTGGCGGCACGTTTACAACAACGTGTAACCGCCATCATGCGCTATGCCGTACAAAGCGGTTTGATCGACTATAACCCAGC
GCAAGATATGGCTGGCGCAGTTGCGACAGGCAAACGAGTTCATAGAGCGGCATTAGAGCTTAAACGCCTACCTGAGTTCT
TAGAACGCATCGATGATTATAAGGGAAGGCCTTTAACTAAACTTGCAGTCAAACTTACCTTATTAGTCTTTATTCGTTCC
AGCGAACTGCGTTTTGCACGTTGGGATGAAATCGATTTTGAAAATGCCATGTGGACGATACCTGCTGAACGAGAAGCGAT
AGAAGGCGTTAAACACTCTCATCGCGGATCAAAAATGCGCACTACCCATTTAGTTCCTTTAAGCCGACAAGCCATTGAGA
TCTTAAAACAGATCTATCAATTCAGTGGTAACCACGAACTGATCTTTATCGGCGATCATAATCCTAGAAAGCCAATGAGT
GAAAATACGGTAAACAATGCATTACGTGTGATGGGCTATGATACTAAGACGGAAGTGTGTGGTCATGGTTTTAGAACAAT
GGCGTGTAGTTCGTTGATTGAGTCAGGTTTGTGGTCAAAGGATGCAGTAGAGAGGCAAATGAGCCACCAAGAGCGTAATT
CAGTCAGGGCTGCTTATATTCATAAAGCAGAACATATTGAGGAAAGGCGGCTGATGGTGCAATGGTGGGCTGATTATCTG
GATGCGAGTAGGGGAGGGGAAATTTCGCCGTTTAGTTTTGCGAAAATAAGTAATGAGATAGTGTGA

Protein sequence :
MALTDAKVRAAKPLDKSYKLTDGDGMHLMVHTNGSKYWRLQYRFGGKQKMLALGVYPDISLAEAREKRDAARKLIANGFD
PSEKRKEVKEEQQKEFNTFEKVARDWHATNQRWSEGHSHRVLKSLEDNIFVAIGKRNIAELKTRDLLEPIKAVEMSGRLE
VAARLQQRVTAIMRYAVQSGLIDYNPAQDMAGAVATGKRVHRAALELKRLPEFLERIDDYKGRPLTKLAVKLTLLVFIRS
SELRFARWDEIDFENAMWTIPAEREAIEGVKHSHRGSKMRTTHLVPLSRQAIEILKQIYQFSGNHELIFIGDHNPRKPMS
ENTVNNALRVMGYDTKTEVCGHGFRTMACSSLIESGLWSKDAVERQMSHQERNSVRAAYIHKAEHIEERRLMVQWWADYL
DASRGGEISPFSFAKISNEIV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 2e-139 78
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 4e-133 68
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 4e-133 68
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 4e-133 68
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 4e-133 68
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 3e-133 68
int AAL51028.1 CP4-like integrase Not tested LEE Protein 7e-132 68
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 3e-132 68
int-phe AAL60261.1 Int-phe Not tested LEE Protein 7e-132 68
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 3e-132 68
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 8e-131 68
int AAK16198.1 Int Not tested PAI-I AL862 Protein 2e-132 68
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 2e-132 68
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 3e-131 68
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 1e-131 68
int AAL51003.1 CP4-like integrase Not tested LEE Protein 1e-131 68
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 7e-132 68
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 1e-131 68
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 2e-131 67
int AAK00456.1 Int Not tested SHI-1 Protein 7e-123 67
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 5e-131 67
int CAC81896.1 integrase Not tested LEE II Protein 2e-121 67
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 6e-117 62
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 6e-117 62
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 6e-76 61
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 1e-89 60
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 3e-110 59
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 2e-103 57
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 2e-103 57
int CAA08754.1 integrase Not tested HPI Protein 3e-101 56
int YP_002346908.1 integrase Not tested HPI Protein 1e-100 56
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 1e-100 56
int2 NP_993013.1 integrase Not tested HPI Protein 1e-100 56
int CAA21384.1 - Not tested HPI Protein 1e-100 56
int CAB59974.1 integrase Not tested HPI Protein 5e-101 56
unnamed AAD17660.1 unknown Not tested HPI Protein 3e-97 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 8e-97 52
int AAD44730.1 Int Not tested SHI-2 Protein 5e-77 48
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-77 47
int CAC39282.1 integrase Not tested LPA Protein 2e-77 47
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 2e-75 47
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 2e-75 47
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 2e-75 47
int ACU09430.1 integrase Not tested LEE Protein 3e-76 46
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 3e-76 46
ECs4534 NP_312561.1 integrase Not tested LEE Protein 3e-76 46
int AAC31482.1 CP4-like integrase Not tested LEE Protein 3e-76 46
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-66 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 3e-65 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
intB YP_002153152.1 prophage integrase VFG1536 Protein 1e-139 78
intB YP_002153152.1 prophage integrase VFG0626 Protein 2e-133 68
intB YP_002153152.1 prophage integrase VFG1693 Protein 1e-132 68
intB YP_002153152.1 prophage integrase VFG0598 Protein 9e-76 47
intB YP_002153152.1 prophage integrase VFG0783 Protein 1e-76 46