Gene Information

Name : nanK (PMI2977)
Accession : YP_002152678.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 3263834 - 3264703 bp
Length : 870 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGAATACATTAGCGATTGATATTGGAGGAACCAAAATCTCGGCAGCATTAATTAGCCGAAATAACCAATTGACACAACA
TCGACAAATAGCAACACCAGCAAGTCCATCTCCAACACAACTTTATGAAGCATTAGTTAGCATTATTACACCATTAAAAA
ACCATGCCGATAGTGTTGCCGTTGCATCAACAGGGATCATTTGTAATGGCATTTTAACCGCATTAAACCCCGATAATTTA
GGTGGATTAAACGATTTTCCTTTAATGGAAACACTATCAACCCTTACCGGATCACCTTGTTGGTTACTTAATGATGCCCA
AGCTGCCACATGGGCTGAGTATTATCATCGTCGTGACACTATATCTGATATGGTGTTTATTACGGTCTCAACCGGCGTTG
GCGGAGGCATTGTTCAGCAAGGGCAGCTACTAATAGGAAAACGTGGTCTTGCAGGCCATTTAGGTCATACCTTAGCTGAT
CCTCGAGGCCCTCGTTGTGGATGTGGCCGCTATGGTTGTGTTGAAGCCATCGCATCGGGGCGTGCGATTGCCTCACAGGC
CGAAGGGGAACTTGCTGGTAAAGATGCTAAGGCAATTTTCAGCGCTTTTCATCAGGGAAACTTACAGGCTACCACCATTA
TTAAACGCTCTGCCAACACCATAGCTAATTTGATCACAAATATTAAAGCTACAACAGATGCTGATTGTGTTGTGCTTGGT
GGCAGTGTGGGGCTTGCTAACGGCTATCTCGAATTGGTTCAAGTTGCTATGGCACAACAACCATTAGCATTACAAGTGCC
GATTGTATCAGCTCACTATCATCATGATGCTGGATTATGGGGCGCAGCCCTATGGTCTAGAGAGCAATAA

Protein sequence : 
MNTLAIDIGGTKISAALISRNNQLTQHRQIATPASPSPTQLYEALVSIITPLKNHADSVAVASTGIICNGILTALNPDNL
GGLNDFPLMETLSTLTGSPCWLLNDAQAATWAEYYHRRDTISDMVFITVSTGVGGGIVQQGQLLIGKRGLAGHLGHTLAD
PRGPRCGCGRYGCVEAIASGRAIASQAEGELAGKDAKAIFSAFHQGNLQATTIIKRSANTIANLITNIKATTDADCVVLG
GSVGLANGYLELVQVAMAQQPLALQVPIVSAHYHHDAGLWGAALWSREQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 4e-40 52
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-30 43
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-30 43
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 7e-30 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nanK YP_002152678.1 N-acetylmannosamine kinase VFG1115 Protein 1e-30 43