Gene Information

Name : thiC (PMI2777)
Accession : YP_002152478.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3046719 - 3048671 bp
Length : 1953 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCCAAAAATCAAACTATCTCTATTAAAGATGTTTCGCCCACTGCGAATAAACAGCGCCCACGTAAAGAACAACGCGA
TGCAGCGCAATCCTTTATTAGCACTATTCAAGGTATTAATTTTCCCAATTCAAAACGTATTTATATCACTGGTACTCGTT
CAGATATTCAAGTGCCAATGCGTGAGATCCAACTTGATAAGACCCTGATCGGTGGCTCAAAAGAAGATCCTATTTTTGAA
GAGAATGAACCTATTCCAGTCTATGACACTTCAGGGCCTTATGGTGATCCAACTTCTCAACTTGACGTTAATCTTGGCTT
AAAAAAAATTCGCCAACCATGGATTGATGCGCGTAATGATACCGAACCTCTTTCACACTTAAGTTCTGATTTCACTCAAC
AACGCCTTACTGATGCAGGATTAGAACATCTACGCTTTCCGTTAAAACCCAGCCCTAGAAAAGCGCTAAATAATAAGAGA
GTGACGCAATTACATTACGCTCGCAAAGGTATTATTACGCCAGAAATGGAATTTATTGCCATTCGAGAAAATATGGGGCG
AGAACGTATTCGTAGCGAAGTATTACGCCAACAACATGCCGGATTTAGCTTTGGTGCACATTTACCTGACAATATTACGC
CTGAGTTTGTACGCCAAGAAGTTGCTGCTGGTCGTGCCATTATTCCTGCCAATATCAATCACCCAGAATCTGAGCCGATG
ATTATTGGCCGTAATTTCTTAGTTAAGGTGAATGCTAATATCGGCAACTCTTCGGTTACCTCATCTATCGAAGAAGAAGT
AGAAAAACTGATTTGGTCAACACGTTGGGGGGCCGATACCGTGATGGATCTGTCAACTGGACGTTATATCCACGAAACAC
GTGAATGGATCATCCGTAATAGCCCAGTCCCTATTGGTACTGTTCCTATTTATCAAGCTCTCGAAAAAGTTAACGGTATT
GCAGAAGATCTCACTTGGGAAATGTTCCGTGATACTTTATTAGAACAAGCGGAACAAGGGGTGGATTATTTCACTATCCA
TGCAGGTGTCCTATTACGCTATGTTCCTATGACCGCAAAACGTTTAACGGGTATTGTCTCTCGTGGTGGTTCAATTATGG
CGAAGTGGTGTTTATCACACCATAAAGAAAATTTCCTCTATACCCACTTCCGAGAGATTTGCGAAATCTGCACCGCTTAT
GATGTTTCATTATCATTAGGTGATGGTCTAAGACCTGGCTCTATCCAAGATGCTAACGATGAAGCACAGTTCGCTGAATT
ACATACCTTGGGTGAATTAACAAAGATTGCTTGGGAATATGATGTACAAGTCATGATTGAAGGCCCAGGTCATGTACCAA
TGCAGATGATACGTCGCAATATGACGGAAGAACTAGAGCATTGTCATGAAGCCCCCTTCTATACATTAGGCCCTCTAACA
ACTGATATAGCACCGGGCTACGATCATTTTACTTCCGGTATTGGCGCTGCAATGATTGGCTGGTTTGGCTGTGCCATGCT
CTGTTATGTCACTCCGAAAGAGCATCTCGGACTCCCCAATAAAGAAGATGTGAAACAAGGTCTTATTACTTATAAAATCG
CCGCCCATGCTGCTGATCTTGCCAAAGGACATCCCGGCGCGCAAATTCGTGATAACGCCATGTCTAAAGCCCGTTTTGAG
TTTCGATGGGAAGATCAATTTAATCTAGCACTTGATCCTGAAACTGCCCGTCAATATCACGATGAAACCTTACCTCAAGC
ATCGGGGAAAGTCGCTCACTTCTGCTCTATGTGTGGACCTAAATTCTGCTCAATGAAGATAACACAAGAAGTGCGTGATT
ATGCAGCAGGTATGGAGCAGATGTCGCAAGCCTTTAAAGCCCATGGTAGTGAGCTATACCACAGTGCAGAAATAGCCAGT
TCCGAGGTAGCTGATAATGAACAGATCCTCTAA

Protein sequence :
MSKNQTISIKDVSPTANKQRPRKEQRDAAQSFISTIQGINFPNSKRIYITGTRSDIQVPMREIQLDKTLIGGSKEDPIFE
ENEPIPVYDTSGPYGDPTSQLDVNLGLKKIRQPWIDARNDTEPLSHLSSDFTQQRLTDAGLEHLRFPLKPSPRKALNNKR
VTQLHYARKGIITPEMEFIAIRENMGRERIRSEVLRQQHAGFSFGAHLPDNITPEFVRQEVAAGRAIIPANINHPESEPM
IIGRNFLVKVNANIGNSSVTSSIEEEVEKLIWSTRWGADTVMDLSTGRYIHETREWIIRNSPVPIGTVPIYQALEKVNGI
AEDLTWEMFRDTLLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHKENFLYTHFREICEICTAY
DVSLSLGDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLT
TDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFE
FRWEDQFNLALDPETARQYHDETLPQASGKVAHFCSMCGPKFCSMKITQEVRDYAAGMEQMSQAFKAHGSELYHSAEIAS
SEVADNEQIL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 72
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 72
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 71