Gene Information

Name : alr (PMI2742)
Accession : YP_002152443.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 2995314 - 2996405 bp
Length : 1092 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGAAAGCGGCAACCGCAGTAATAGATCGCCGCGCTCTGCGTCACAATTTTCAGCATGTAAGAGACTATGCACCACATAG
CCACCTGATAGCTGTCGTGAAAGCAAACGCTTATGGTCATGGGTTATTAGAAACAGCATATACTTTAATGGATGATGCTG
ATTGTTTTGGCGTAGCACGTATCGGTGAAGCCTTAACATTACGTAGTGGGGGGATTGTGAAACCCATCCTACTACTTGAA
GGCTTCTTTGATGCTGTTGATTTACCCATTTTGGTGGTTAACCATATTGAGACTGTTGTTCATAGTGAAGAGCAACTCGA
AGCGTTAGAAAATGCCGATTTAGAAGAACCCGTAAAAGTCTGGATGAAGCTCGATACTGGAATGCATCGTTTAGGCGTCC
GTCCTGAAGAAGCTGAGGCTTTTTATCAACGACTTTGTGCTTGTAAAAATGTCCAACAACCCGTCAATTTGGTCAGTCAC
TTTAGTCGCGCGGATGAGCCTGATATTCCTGAAGTCACACAAAATCAAATTCAGCTATTTCAAGCCTTTATCCAAGATAA
AGCGGGTGATAAATCTATCGCTGCTTCTGCGGGAATTTTATTTTGGCCACAAGTCCATTATCAATGGGTTCGCCCTGGGA
TCATCACATACGGTATCTCACCAACGGGTGATAACAGAACAGGTAAAGACTTTGGTTTAACCCCGGCAATGACATTAAAA
ACGAGCCTTATTGCGGTTCGTAAACATAAAGCAGGTGAACCCGTTGGTTATGGTGGTACATGGGTAAGTGAAAAAGATAC
TTATCTGGGTGTTATTGCTATCGGTTATGGTGATGGTTACCCACGTAGTGCACCTTCTGGTACTCCTGTTTGGATCAACG
GTCGAAAAGTGCCGATTGTTGGACGCGTTTCTATGGATATGATCAGCGTCGATTTGGGATCTGAGCTAATTGATCGTGTC
GGTGATGAAGCTATTTTATGGGGAGATGTGCTACCCGTAGAAGAAATTGCCAAATATAGTGGTATTAGCGCGTACGAATT
AATTACCAAATTAACTTCGCGCGTCATTATGGAATACCTAGACGAACAATAG

Protein sequence :
MKAATAVIDRRALRHNFQHVRDYAPHSHLIAVVKANAYGHGLLETAYTLMDDADCFGVARIGEALTLRSGGIVKPILLLE
GFFDAVDLPILVVNHIETVVHSEEQLEALENADLEEPVKVWMKLDTGMHRLGVRPEEAEAFYQRLCACKNVQQPVNLVSH
FSRADEPDIPEVTQNQIQLFQAFIQDKAGDKSIAASAGILFWPQVHYQWVRPGIITYGISPTGDNRTGKDFGLTPAMTLK
TSLIAVRKHKAGEPVGYGGTWVSEKDTYLGVIAIGYGDGYPRSAPSGTPVWINGRKVPIVGRVSMDMISVDLGSELIDRV
GDEAILWGDVLPVEEIAKYSGISAYELITKLTSRVIMEYLDEQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 1e-55 41