Gene Information

Name : murD (PMI2072)
Accession : YP_002151791.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 2235538 - 2236848 bp
Length : 1311 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCAAATTATCAGGGGAAAAAAGTTGTTATCGTGGGACTAGGCATTACTGGTCTATCCTGCGTTGACTTTTTTATCCG
CCAAGGTGTAACACCTAAAGTGATAGATACTCGCCAGCATCCCGCGGGTTTAGATAAGCTACCTGCTGATGTTGAGTATC
ATACGGGGAGTTTTCATCAAGTATGGCTTAATGATGCTGATTTAATTGTCTCAAGTCCGGGTATTGCGTTATCAACGCCT
GAGTTAGTTGAAGCGCGAGATCATGGAGTGGAAATTGTCGGTGATATTGAGCTATTTTGCCGTGAGGCAAAAGCACCTAT
TGTTGCGATAACAGGCTCTAATGGCAAAAGTACCGTAACGACGTTGGTGGGGGAAATGGCTAAAGCTGACGGGATCCCTG
TCGGTGTCGGTGGCAATATTGGTGTACCTGCTTTAACGTTATTAACACAGCCTTATGACTTATATGTCTTAGAGCTATCG
AGCTTTCAATTAGAGACAACCTATAGCTTAACAGCGGCGGCTGCTACGGTATTAAATATTAGCGAAGATCATATGAATCG
CTATCCGTTAGGATTAGAACAATACCGTGAAGCTAAATTACGTATTTATGATAATGCTAAAACCTGTGTCTATAACGCAG
ATGATGTTCTGACATTGCCTTTAGCTGGCAAAGATGCACGTTGTGTGAGTTTTGGTATCGGACAAGGGGATTATCAGCTT
GATAATACCAATCGTTACTTGAACGTAAATGGTGAAAATCTTCTTGCCACTTCACAGATGTTCCTTTCTGGTCAACACAA
TTACACCAATGCATTAGCCGCATTAGCGTTAGCTGATGCAGTGGGAATTTCTCGTAAAGCATCACTGGCTGTTTTAAACA
CCTATCATGGCCTTGCTCATCGTTTCCAATTAGTTTACTCCCATAATGGGGTACGTTGGATCAATGATTCTAAAGCGACT
AATGTAGGTAGCACAGAAGCAGCTTTAAGAGGGCTTGAAGTAGAAGGGACTTTGCACCTGTTGTTAGGTGGGGACGGTAA
GTCTGCTGATTTTAGCGCGCTATTACCTTATCTCAGTGGCGATAATATTCGCTTATATTGCTTTGGACAAGATGGTCAAG
CATTGGCAAATTTACGACCACAAGTCTCACAATTAACCGCGACTATGGAAGAGGCGATGCGATTACTTGCACCAACAGTG
CAAACTGGCGATATGGTGCTACTTTCACCCGCTTGTGCAAGTCTAGATCAGTTTAAAAGTTTCGAACAACGTGGTGATGA
GTTTGCCCGTTTAGCGCAGGAGCTTGGCTGA

Protein sequence :
MANYQGKKVVIVGLGITGLSCVDFFIRQGVTPKVIDTRQHPAGLDKLPADVEYHTGSFHQVWLNDADLIVSSPGIALSTP
ELVEARDHGVEIVGDIELFCREAKAPIVAITGSNGKSTVTTLVGEMAKADGIPVGVGGNIGVPALTLLTQPYDLYVLELS
SFQLETTYSLTAAAATVLNISEDHMNRYPLGLEQYREAKLRIYDNAKTCVYNADDVLTLPLAGKDARCVSFGIGQGDYQL
DNTNRYLNVNGENLLATSQMFLSGQHNYTNALAALALADAVGISRKASLAVLNTYHGLAHRFQLVYSHNGVRWINDSKAT
NVGSTEAALRGLEVEGTLHLLLGGDGKSADFSALLPYLSGDNIRLYCFGQDGQALANLRPQVSQLTATMEEAMRLLAPTV
QTGDMVLLSPACASLDQFKSFEQRGDEFARLAQELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 1e-56 44
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 1e-56 44