Gene Information

Name : ireA (PMI1945)
Accession : YP_002151668.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Virulence
Product : iron-regulated outer membrane virulence protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG4771
EC number : -
Position : 2091575 - 2093614 bp
Length : 2040 bp
Strand : -
Note : iron-responsive element (ireA); ireA gene is located on pathogenicity island I (PAI I); outer membrane protein

DNA sequence :
ATGAAATTTAAAATAAGTGCTTTAACAGCCTGTATTTTAATGACTTCTTATTCACTACATGCACAAGAAGATAAAGTAGA
ACGATTAGTTGTATCAGCCTCAGGGTTTGCACAGCAACAAACAGATGCACCCGCTAGCATTACGGTAATCAACAAAGAAC
AATTAGAGAAAAAACCGATACACGATCTTGCTGATGCCGTAAAAGGGGTTGAAGGCGTCAGTGTGAATGGTAATGCAAAT
AAACAAGAAATTACTATTCGTGGCTTACCCGGAGAATACACACTGATTTTGGTTGATGGCAGACGTCAAAATAGTCGTGA
ATCACGCCCTAATGGGAGTGGTGGATATGAAGGTGGATTTATTCCTCCTGCGGATGCCATTGAACGGATCGAGGTAATAC
GTGGGCCAATGTCATCACTTTATGGCTCAGATGCGATGGGCGGTGTGATTAATATTATTACTAAGCCTGTTACTAAAGAG
TGGCATGGTGCAGTTTCCATGGGGGGAACATTGCAACATAACCGTGACGCGGGAGATTCTATCAATGGTGATTTTTATCT
TTCAGGCCCATTAATTGAAGATAAATTAGGTTTACAACTTTATGGTAGTAGCTACTTACGTGCAGAAGATAAAATTACGT
ATGGGCAAGGGCGTAACGATAATAAAAATATTACGGCCAAATTAGCCTTTACTCCTACAGATAACCAAACCATTTTATTA
GAAGCTGGGCGCAATTCGCTACAACGCACGACAACACCGGGTAAATCGATGAGCGAATTTACCAATCGTGGTGGACGTCT
TGATAAAAACAAAATGTTAGAAACGAATAATGACCGTAACCATTGGGCATTAACTTATAAAAATCAGTTTGATATTTTGC
ACTCTGAGTTAAGTGTTTATCAAGAGCAAACCAAGCGTGTTCAAAAGACGGAAGGTGTAGATAAAGCGACAGGAAATAGC
TACAAATATTATGAAGATCGCCGCCCTGAAATCACTAATACTGTTTTCGATGCTAAATTTACCGCATTCCTTCCTGATAA
TGTGATGACTTTTGGTGGTCAATACCAATATGCACGTTTAAAAGACGAATCTTCAGTCGGTGGTAAAGAGGTCAAACAAT
CTACGATCACCGCTGATCAAAAAGCGTTATTTTTAGAAGATGAATTTAGTGTCACAGATAATTTAGCCCTAACTGGGGGA
ATACGTCTTGATGATCATGAATACTATGGTAAGCACTGGAACCCAAGAGCATACGCGGTTTACCATTTAACCGACGAATT
TACCATCAAAGGAGGGATTGCTAAGGCCTTTAAAGCCCCGAGTTTACGAGAAATTAGCCCTCAATATGGTACATCAACGG
AAAAAGGGCGAGCGATTATGTATGGTAATCGTGACTTAAAACCTGAAACTTCGGTTAGCCAAGAAATTGGTGTTGGTTAT
GACAATGGTGATGGTTTTACCGCCAATGTGACCTTCTTTAATACAGAATTTAAAGATAAGCTTACCAACTACGATACGGG
TGAAATCGATCCTATTACCGGATTAAAACTGTACCAATATGATAATGTGGGTAAAGCTAATATTAAAGGGATTGAAACCG
CGGTTGCATTCCCTGTCGCTGATAATTGGCGAGTAAGTGCTAATTACACTTATATCAACTCTAAGCGTAAAAGTGATGAC
GAAAAATTAGGCTCTGGTGAATCATTAAAAGGTTATCCATTGGATATGACACCAAAACATAGCGCCAATGCGCGTGTTGA
TTGGCAATACGATGAAGCTACCAGTTTCTATGCCAATACTGCCTATACTGGTAAGCAAATTTGGGCGGCTCAACGAAATG
GTTATACTGGCGCTCGTTATCGTAGTGGTTATACAACCTTTGATTTAGGAATGACCTATAACTTTAATAAAAATACCATG
CTAAATTTAGCCGTATTGAATATTACTGATGAAACGGGTCCTGCGGTCAACGATAAAGGGGGGAACTGGGTCGTTGATGA
AGGCCGTCGTTATTGGGCAAATATCAAATATAGTTTTTAA

Protein sequence :
MKFKISALTACILMTSYSLHAQEDKVERLVVSASGFAQQQTDAPASITVINKEQLEKKPIHDLADAVKGVEGVSVNGNAN
KQEITIRGLPGEYTLILVDGRRQNSRESRPNGSGGYEGGFIPPADAIERIEVIRGPMSSLYGSDAMGGVINIITKPVTKE
WHGAVSMGGTLQHNRDAGDSINGDFYLSGPLIEDKLGLQLYGSSYLRAEDKITYGQGRNDNKNITAKLAFTPTDNQTILL
EAGRNSLQRTTTPGKSMSEFTNRGGRLDKNKMLETNNDRNHWALTYKNQFDILHSELSVYQEQTKRVQKTEGVDKATGNS
YKYYEDRRPEITNTVFDAKFTAFLPDNVMTFGGQYQYARLKDESSVGGKEVKQSTITADQKALFLEDEFSVTDNLALTGG
IRLDDHEYYGKHWNPRAYAVYHLTDEFTIKGGIAKAFKAPSLREISPQYGTSTEKGRAIMYGNRDLKPETSVSQEIGVGY
DNGDGFTANVTFFNTEFKDKLTNYDTGEIDPITGLKLYQYDNVGKANIKGIETAVAFPVADNWRVSANYTYINSKRKSDD
EKLGSGESLKGYPLDMTPKHSANARVDWQYDEATSFYANTAYTGKQIWAAQRNGYTGARYRSGYTTFDLGMTYNFNKNTM
LNLAVLNITDETGPAVNDKGGNWVVDEGRRYWANIKYSF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAL67402.1 IrgA-like protein Virulence PAI II CFT073 Protein 0.0 57
ireA YP_854314.1 iron-regulated outer membrane virulence protein Virulence PAI I APEC-O1 Protein 0.0 57
c5174 NP_757022.1 iron-regulated outer membrane virulence protein Not tested PAI II CFT073 Protein 0.0 57
ireA AAZ04447.1 iron-regulated outer membrane protein Virulence PAI I APEC-O1 Protein 0.0 57