Gene Information

Name : fliI (PMI1633)
Accession : YP_002151364.1
Strain : Proteus mirabilis HI4320
Genome accession: NC_010554
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1746683 - 1748056 bp
Length : 1374 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGACCGCAAGATTGGGGCGTTGGTTAGAAAAACTCGCTGATGCAGAATCTCGTTTAAATAAAATTCCGCGCATTCGCCA
ATATGGTCGCTTAACCCGTGCTACAGGCTTAGTCATGGAAGCTAAGGGGCTAGTTATGCCCCTTGGCTCTACCTGCTTAA
TAGAACGTACCATTGGTAAAACGGTTGAAGAAGTTGAAAGTGAAGTCGTCGGATTTAACGGTAGCCAAATGTTACTCATG
CCACTACAAGAAGTGGAAGGATTAACCCCAGGTGCTCGAGTCTACGCTCAATCGATCCCCGGTCGTGAAGGCGAAGGCCG
ACAATTACCCCTTGGTGATGCCTTATTAGGCCGCGTACTTGATGGCTCAGGTGATCCGCTAGATGGTTTACCGCCGCCAG
ATACCAGTTATCGTGCACCACTGATTACACCACCTATCAACCCATTACAACGTACCCCCATTACAGATGTACTTGATGTG
GGTGTACGTGCCATCAATGCACTGCTTACGGTCGGTCGTGGCCAACGTATGGGACTCTTTGCCGGCTCGGGTGTCGGGAA
AAGTGTTCTATTAGGTATGATGGCGCGTTTTACTCAAGCCGACGTCATTGTCGTAGGGCTTATTGGTGAACGTGGTCGTG
AAGTTAAAGACTTTATTGAGAATATCCTAGGTAAAGAAGGATTAGCACGCTCGGTGGTAGTAGCAGCACCTGCTGATGTT
TCACCACTCTTACGAATGCAAGGTGCTTCTTATGCAACCCGTATTGCCGAAGATTTTCGTGATCGCGGTAAACATGTTTT
ATTAATTATGGATTCGTTAACTCGCTATAGCATGGCGCAGCGTGAAATTGCCTTAGCCGTTGGTGAACCGCCGGCGACAA
AAGGTTATCCCCCTTCTGTATTTGCAAAATTACCCGCACTTGTTGAGCGTGCCGGTAATGGCGTTGATGGTGGTGGCTCC
ATTACTGCTTTCTATACCGTGTTAACAGAAGGTGACGATCAGCAAGATCCAATCGCTGATTCTGCCCGTGCTATTTTGGA
TGGCCATATCGTGCTTTCGCGTTCACTGGCGGAATCGGGTCACTACCCTGCTATTGATATTGAAGCGTCCATTAGCCGTG
CGATGACCTCACTGATTGATAAAACACATTATCGCCGAGTACAAGTATTTAAGCAGCTATTATCCAGTTATCAGCGCAAT
CGCGACTTAATTAATGTAGGGGCTTATGCCACAGGCAGTGATCCTATGCTGGATAAGGCGATTGCCCTTTATCCATCATT
AGCAAAATTCTTACAACAAGATATTCAAGAGCAATGTAGCTATCAACATGCTTGTGAACAACTTAATCAACTGATCACAC
TAGATTCATTCTGA

Protein sequence :
MTARLGRWLEKLADAESRLNKIPRIRQYGRLTRATGLVMEAKGLVMPLGSTCLIERTIGKTVEEVESEVVGFNGSQMLLM
PLQEVEGLTPGARVYAQSIPGREGEGRQLPLGDALLGRVLDGSGDPLDGLPPPDTSYRAPLITPPINPLQRTPITDVLDV
GVRAINALLTVGRGQRMGLFAGSGVGKSVLLGMMARFTQADVIVVGLIGERGREVKDFIENILGKEGLARSVVVAAPADV
SPLLRMQGASYATRIAEDFRDRGKHVLLIMDSLTRYSMAQREIALAVGEPPATKGYPPSVFAKLPALVERAGNGVDGGGS
ITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRSLAESGHYPAIDIEASISRAMTSLIDKTHYRRVQVFKQLLSSYQRN
RDLINVGAYATGSDPMLDKAIALYPSLAKFLQQDIQEQCSYQHACEQLNQLITLDSF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 8e-71 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-64 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-64 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-64 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-64 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-73 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-73 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-75 48
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-76 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-76 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-76 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-64 48
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 9e-76 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-75 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-75 47
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-69 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-69 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-69 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 6e-67 45
escN AAK26715.1 EscN Virulence LEE Protein 2e-67 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 6e-67 45
escN AAL57542.1 EscN Virulence LEE Protein 2e-67 45
escN YP_003236088.1 translocator EscN Virulence LEE Protein 5e-67 45
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-67 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 2e-67 45
escN AAC38383.1 EscN Virulence LEE Protein 5e-67 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-67 45
escN AAC31513.1 L0034 Virulence LEE Protein 4e-67 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-67 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-59 44
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-67 44
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-67 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-62 43
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-60 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 4e-62 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-61 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 5e-62 42
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-63 42
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-62 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 4e-67 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-66 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_002151364.1 flagellum-specific ATP synthase VFG2331 Protein 5e-153 81
fliI YP_002151364.1 flagellum-specific ATP synthase VFG2499 Protein 5e-132 67
fliI YP_002151364.1 flagellum-specific ATP synthase VFG1254 Protein 2e-114 63
fliI YP_002151364.1 flagellum-specific ATP synthase VFG0515 Protein 1e-64 49
fliI YP_002151364.1 flagellum-specific ATP synthase VFG2144 Protein 1e-77 46
fliI YP_002151364.1 flagellum-specific ATP synthase VFG0192 Protein 1e-73 46
fliI YP_002151364.1 flagellum-specific ATP synthase VFG0812 Protein 2e-67 45
fliI YP_002151364.1 flagellum-specific ATP synthase VFG0730 Protein 3e-67 45
fliI YP_002151364.1 flagellum-specific ATP synthase VFG0048 Protein 2e-69 44
fliI YP_002151364.1 flagellum-specific ATP synthase VFG0390 Protein 1e-70 44
fliI YP_002151364.1 flagellum-specific ATP synthase VFG1778 Protein 3e-55 41