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Name : topB (PMI1496) Accession : YP_002151227.1 Strain : Proteus mirabilis HI4320 Genome accession: NC_010554 Putative virulence/resistance : Unknown Product : DNA topoisomerase III Function : - COG functional category : L : Replication, recombination and repair COG ID : COG0550 EC number : 5.99.1.2 Position : 1586782 - 1588749 bp Length : 1968 bp Strand : - Note : decatenates replicating daughter chromosomes DNA sequence : ATGAGATTATTTATTGCAGAAAAACCCAGCCTTGCTCGAGCTATTGCTGATGTATTACCAAAACCGCATAAACGTGGTGA TGGTTTTATTGTTTGTGGTGATAACCAGTATGTGACGTGGTGTGTTGGTCATTTACTTGAGCAGGCTGAGCCGGATGCAT ATGATCCGCGCTATGCGCGTTGGTCGTTAGATGATTTGCCCATTATTCCGAATAAATGGCAACTCAAACCGCGCGCTGAT GTGAAAAAACAGCTAGATACGATCAACACATTACTAAAACAAGCCGATGAAGTGATCCACGCAGGAGACCCCGATCGCGA AGGGCAACTGTTAGTAGATGAAGTACTTAATTACCTTAATATTAGTGATGCTCAAAGGAAACAGGCACGCCGCTGCCTGA TTAACGATTTAAACCCCGCCGCGGTATCTCGAGCAATTGATAAGCTCCGCTACAATCATGAATTTATTCCATTATGTGTT TCTGCCTTAGCAAGAGCGAGGGCGGATTGGCTATATGGCATTAACATGACACGCGCTTACACGTTATTAGGACAGCGCAA TGGTTACCAAGGCGTACTCTCTGTTGGGCGAGTACAAACCCCGGTGCTAGGTTTAGTCGTACGCCGTGATGAAGAAATTG AAAACTTTGTACCGAAAGATTTTTTTGAAGTCAAAGCGCATATCGTTACTCCTGCAGATGAGCGATTTACCGCTATTTGG CAGCCGAGTGAACACTGCGAGCCTTGGCAAGATGAAGAAGGGCGTTTATTACATCGCAAATTAGCAGAGCATGTTGTTGA TAGAATAGCTGGCAAGCCTGCTAATGTTACCGATTATCAAGATAAACAAGAGTCTGAAATAGCACCTTTGCCTTTTTCAT TATCTGCTTTACAAATTGAAGCGGCGAAACGCTTTGGTTTAAGCGCTCAACAAGTGTTAGACACATGTCAACGCTTATAT GAAACGCATAAACTTATTACTTATCCACGCTCCGATAGTCGCTATCTCCCTGATGAACACTTTGCTGGGCGTCATGCGGT GATGAATGCCATTAGTGTGCATGATAATAGTCTTTTACCACAAGAAACATTAGATATTGATAAAAAGAACCGTTGCTGGG ATGACAAGAAAGTAGATGCGCACCATGCCATTATTCCTACTGCGAAAACAGGTAATATTTCATTAAGTGAAAATGAAAAG AATATTTACTATTTGATTGCCCGACAATATCTAATGCAATTTATGCCAGATGCGGTGTACCGCAAATGTGTGATTGAACT CGATATTGAGAATGGAAAGTTTATTGCTAAGGCACGATTTTTAGCACAAGCCGGCTGGCGTACCTTATTAGGTAGTAAAG AGCAAGATGCGGAAAATGATGGTAGCGCCTTACCTATTGTGGCTAAAGGTGATGAGTTACTTTGTGAAAAAGGCGAAATT GTTGCCAAGCAGACCCAACCACCAAGACCTTTTACAGATGCTACGCTACTTTCGGCTATGACCGGTATTGCACGTTTTGT GCAAGACAAAGAGCTAAAGAAAATCCTAAGAGCGACGGATGGGCTAGGTACTGAAGCGACTAGGGCTGGTATTATTGAAT TACTGTTTAAACGCGGCTTTCTGCAAAAGAAAGGGCGAGCTATCAACTCGACACCAGCAGGAAGAGCATTAATTCATGTT TTGCCAGATATGGCGACATTACCCGATATGACCGCTCATTGGGAATCAATATTAACGCAAATTAGTGAGAAGCAATTTAA GTATCAAGATTTTATGATGCCATTAAGTAACACACTATTTGAATTAATTACTCAAGCTAAACGTCGTCCTAATATTCAAG CGTTTAGAAACCTGCCTGCGCCTGCGCAGAATAAAAAACGTAAAGGTGCGACGAAAAAAAGTGCACAAGGGAAAAGTCGT TCAGCGCAGTCTCAATCTACGAATCGCAATATAAAGAGTGATGCTTAG Protein sequence : MRLFIAEKPSLARAIADVLPKPHKRGDGFIVCGDNQYVTWCVGHLLEQAEPDAYDPRYARWSLDDLPIIPNKWQLKPRAD VKKQLDTINTLLKQADEVIHAGDPDREGQLLVDEVLNYLNISDAQRKQARRCLINDLNPAAVSRAIDKLRYNHEFIPLCV SALARARADWLYGINMTRAYTLLGQRNGYQGVLSVGRVQTPVLGLVVRRDEEIENFVPKDFFEVKAHIVTPADERFTAIW QPSEHCEPWQDEEGRLLHRKLAEHVVDRIAGKPANVTDYQDKQESEIAPLPFSLSALQIEAAKRFGLSAQQVLDTCQRLY ETHKLITYPRSDSRYLPDEHFAGRHAVMNAISVHDNSLLPQETLDIDKKNRCWDDKKVDAHHAIIPTAKTGNISLSENEK NIYYLIARQYLMQFMPDAVYRKCVIELDIENGKFIAKARFLAQAGWRTLLGSKEQDAENDGSALPIVAKGDELLCEKGEI VAKQTQPPRPFTDATLLSAMTGIARFVQDKELKKILRATDGLGTEATRAGIIELLFKRGFLQKKGRAINSTPAGRALIHV LPDMATLPDMTAHWESILTQISEKQFKYQDFMMPLSNTLFELITQAKRRPNIQAFRNLPAPAQNKKRKGATKKSAQGKSR SAQSQSTNRNIKSDA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| topB | NP_458624.1 | topoisomerase B | Not tested | SPI-7 | Protein | 1e-109 | 42 |
| topB | NP_807836.1 | DNA topoisomerase III | Not tested | SPI-7 | Protein | 1e-109 | 42 |
| topB | AAF14809.1 | topoisomerase B | Not tested | SPI-7 | Protein | 9e-110 | 42 |
| topB1 | YP_005176228.1 | DNA topoisomerase III | Not tested | ICEPmu1 | Protein | 2e-111 | 41 |
