Gene Information

Name : guaA (BamMC406_1891)
Accession : YP_001808589.1
Strain :
Genome accession: NC_010551
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 2105431 - 2107050 bp
Length : 1620 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACGACAAAATCCTGATTCTCGACTTCGGTTCGCAAGTCACCCAACTGATCGCGCGCCGCGTGCGCGAAGCGCACGT
CTACTGCGAAATCCACCCGAACGACGTGTCCGACGAGTTCGTCCGCGAGTTCGCGCCGAAGGCGGTGATCCTGTCGGGCA
GCCACGCGAGCACGTACGAAGACCATCAACTGCGCGCGCCGCAGGCCGTGTGGGATCTCGGCGTGCCGGTGCTCGGCATC
TGCTACGGCATGCAGACGATGGCCGTGCAGCTCGGCGGCAAGGTCGAGTGGAGCGACCACCGCGAGTTCGGCTATGCGGA
AATGCGCGCGCACGGCCATACGCGCCTGCTCGACGGCATCGAGGATTTCACGACGGCCGAAGGCCACGGCATGCTGAAGG
TCTGGATGAGCCACGGCGACAAGGTTGCCGAGCTGCCGCCGGGCTTCGCGTTGATGGCGTCGACGCCGAGCTGCCCGATC
GCCGGCATGGCCGACGAGGCGCGCGGCTACTACGCGGTGCAGTTCCACCCGGAAGTCACGCACACGGTGAAGGGCCGCCA
GATCATCGAACGCTTCGTGCTGCAGATCGCCGGCGCGAAGCCCGACTGGATCATGAGCAACCACATCGAGGAAGCCGTCG
CGAAGATTCGCGAGCAGGTCGGTGATGAGGAAGTGATTCTCGGCCTGTCGGGCGGCGTCGATTCGAGCGTCGCGGCCGCG
CTGATCCACCGCGCGATCGGTGACCAGCTGACCTGCGTGTTCGTCGACCACGGCCTGCTGCGCCTGAACGAGGGCAAGAT
GGTGCTCGACATGTTCGAGGGCCGCCTGCATGCGAAGGTCGTGCACGTCGACGCATCCGAGCAGTTCCTCGGCCACCTGA
CCGGGGTGACCGATCCGGAAGCGAAGCGCAAGATCATCGGCCGTGAATTCGTCGAGGTGTTCCAGGCCGAAGCGAAGAAG
CTGTCGAAGGCGAAGTGGCTTGCGCAGGGCACGATCTATCCGGACGTGGTCGAGTCGGGCGGCACGAAGACGAAGAAAGC
GACGACGATCAAGAGCCACCACAACGTCGGCGGCCTGCCGGAAACACTCGGCCTGAAGCTGCTCGAACCGCTGCGCGACC
TGTTCAAGGACGAAGTGCGCGAACTGGGCGTCGCGCTCGGTCTGCCGCCGGAGATGGTGTACCGCCATCCGTTCCCGGGC
CCGGGCCTCGGCGTGCGGATTCTCGGCGAAGTGAAGCGCGAATACGCGGACTTGCTGCGTCGCGCGGATGCGATCTTCAT
CGAGGAACTGCGCGGCACGACCGCGACGACGCAGGACGCGGCAGCCGGCCTGTGCGGCGAGGCCGACGTCGGCAAGACCT
GGTACGACCTGACGAGTCAGGCATTCGCGGTGTTCCTGCCGGTGAAGTCGGTCGGCGTGATGGGCGATGGCCGCACGTAC
GACTACGTGACGTCGCTGCGCGCGGTGCAGACCACCGATTTCATGACCGCGCACTGGGCGCACCTGCCGTATGCGCTGCT
CGGCCGTGCGTCGAACCGGATCATCAACGAGGTGCGCGGGATCAACCGTGTGGTGTACGACATCTCGGGCAAGCCGCCGG
CGACGATCGAATGGGAGTGA

Protein sequence :
MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDEFVREFAPKAVILSGSHASTYEDHQLRAPQAVWDLGVPVLGI
CYGMQTMAVQLGGKVEWSDHREFGYAEMRAHGHTRLLDGIEDFTTAEGHGMLKVWMSHGDKVAELPPGFALMASTPSCPI
AGMADEARGYYAVQFHPEVTHTVKGRQIIERFVLQIAGAKPDWIMSNHIEEAVAKIREQVGDEEVILGLSGGVDSSVAAA
LIHRAIGDQLTCVFVDHGLLRLNEGKMVLDMFEGRLHAKVVHVDASEQFLGHLTGVTDPEAKRKIIGREFVEVFQAEAKK
LSKAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVALGLPPEMVYRHPFPG
PGLGVRILGEVKREYADLLRRADAIFIEELRGTTATTQDAAAGLCGEADVGKTWYDLTSQAFAVFLPVKSVGVMGDGRTY
DYVTSLRAVQTTDFMTAHWAHLPYALLGRASNRIINEVRGINRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-117 49
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-117 49
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-117 49
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-107 49