Gene Information

Name : tktA (cce_4627)
Accession : YP_001806041.1
Strain :
Genome accession: NC_010546
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 4779457 - 4781469 bp
Length : 2013 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGGTCGCTGCCACCCAGTCACTCGAAGAACTTTGTATTAATTCTATTCGTTTTTTAGCAGTTGATGCTGTAGAAAAAGC
AAAATCAGGACACCCAGGACTGCCCATGGGTGCGGCTCCGATGGCTTATGTCCTGTGGGATAAGTTTATGCGGTTCAATC
CCAAGAATCCCAAATGGTTTAACCGCGATCGCTTCATTTTATCGGCGGGTCATGGCTGTATGTTACAGTATGCCCTACTC
TATTTGACCGGTTACGATAGTGTCACCATTGAAGACATTAAACAATTCCGTCAATGGGGATCGAAAACTCCCGGACACCC
AGAAAACTTTGAAACCGAAGGGGTCGAAGTGACCACTGGACCCCTAGGACAAGGGATCGCCAACGGTGTGGGATTAGCTT
TAGCAGAAGCCCATTTAGCAGCTACCTTCAACAAACCTGATGCAACCATTGTGGATCATTACACCTATGTCATCCTAGGG
GATGGTTGCAATATGGAAGGGGTAGCCAGTGAAGCTTGTTCGGCTGCTGGTCACTGGGGGTTAGGCAAACTCATCGCCCT
TTATGACGATAACCACATCTCTATTGATGGTTCTACCGATGTAGCCTTTACCGAAGATGTATCCAAACGCTTTGAAGCTT
ACGGTTGGCACGTTCTCCATGTCGAAAATGGTAACACCGATTTAGATGGCATTGCCAAGGCGATCGAAGAAGCCAAAAAA
GTCACCGATAAGCCTTCGATGATCAAAGTTACCACCACCATCGGGTATGGTTCCCCCAACAAACAAAACACCGCCGGGGT
TCACGGGGCTGCTTTAGGTCCGGATGAAGTTGCCTTAACTCGTCATAACTTAGGTTGGGATCATGAACCTTTTGTTGTCC
CTCAAGATGTGCTAAGCCACATGAATAAAGCCATCGAACGGGGGGCAAACTATGAAGAGGAATGGAATAAAGCCTTTGAA
ACTTACAAGGCTAAATATCCCGCAGAAGCAGCTGAGTTTGAACGCTATTTAAGTGGCCAACTGCGTGAGGGTTGGGAAAA
AGAACTACCCACCTTTACCCCCGATGATGCAGCCAATGCTACCCGTAAACATTCTGCTGCTATCCTCAATAAACTAGCTC
CTGTGATTCCTGAATTAATCGGCGGATCGGCTGATTTAACCCACTCTAACTTAACGGAATTAAAGGTTTCCGGTGATTTC
CAAAAAGGACAGTATGGTAACCGTAACGTTCACTTTGGAGTTAGAGAACATGGAATGGGGGCTATCTGTAACGGAATGGC
CTTACATGGTTCGGGTTTAATTCCTTATGGTGCGACCTTCCTGATCTTTACTGATTATATGCGGGCTTCTATCCGTTTAT
CGGCCTTATCTCAAGCTGGAGTGATCTGGGTGATGACTCACGACTCCATCGGACAAGGGGAAGATGGTCCGACTCACCAA
CCCGTGGAAGTGTTGGCTTCTTTACGAGCTATTCCTAATTTAACCGTTATTCGTCCTGCGGATGGTAATGAGTGTTCTGG
AGCTTATAAAATAGCTATTGAGAAGGCTAAGCAAAATGCCCCTACTTTGATGGCTTTCACTCGTCAGAATGTACCTAACC
TCCCCGGAACTTCTATCGAAGGAGTAACTAAGGGAGCTTATACTATTGTCGACTGTGACGGAACCCCTGACATCATCCTC
ATTGGAACCGGTTCAGAAGTGAGTCTTTGTGTCACGGCTGCTGAAAAATTAACCGCCGAAGGTAAGAAAGTTCGGGTGGT
TTCTATGCCTTCTTGGGAGCTATTTGAAGCGCAAGACGAAGCTTATAAAGAATCTGTTCTTCCTAAAGCTGTCACGAAAC
GGGTATCCGTTGAAGCCGGTGTTAGCTTTGGTTGGGCCAAATATGTCGGAACCGAAGGTGATACCGTCAGTATTGATACT
TTTGGGGCTTCTGCTCCGGGTGCAACCTGCATGGAAAAATTTGGCTTTAGTGTAGACAATGTTTTAGCGAAAGCAAAAGC
TGTTTTAGGATAA

Protein sequence :
MVAATQSLEELCINSIRFLAVDAVEKAKSGHPGLPMGAAPMAYVLWDKFMRFNPKNPKWFNRDRFILSAGHGCMLQYALL
YLTGYDSVTIEDIKQFRQWGSKTPGHPENFETEGVEVTTGPLGQGIANGVGLALAEAHLAATFNKPDATIVDHYTYVILG
DGCNMEGVASEACSAAGHWGLGKLIALYDDNHISIDGSTDVAFTEDVSKRFEAYGWHVLHVENGNTDLDGIAKAIEEAKK
VTDKPSMIKVTTTIGYGSPNKQNTAGVHGAALGPDEVALTRHNLGWDHEPFVVPQDVLSHMNKAIERGANYEEEWNKAFE
TYKAKYPAEAAEFERYLSGQLREGWEKELPTFTPDDAANATRKHSAAILNKLAPVIPELIGGSADLTHSNLTELKVSGDF
QKGQYGNRNVHFGVREHGMGAICNGMALHGSGLIPYGATFLIFTDYMRASIRLSALSQAGVIWVMTHDSIGQGEDGPTHQ
PVEVLASLRAIPNLTVIRPADGNECSGAYKIAIEKAKQNAPTLMAFTRQNVPNLPGTSIEGVTKGAYTIVDCDGTPDIIL
IGTGSEVSLCVTAAEKLTAEGKKVRVVSMPSWELFEAQDEAYKESVLPKAVTKRVSVEAGVSFGWAKYVGTEGDTVSIDT
FGASAPGATCMEKFGFSVDNVLAKAKAVLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-153 53
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-150 52