Gene Information

Name : leuS (cce_4237)
Accession : YP_001805651.1
Strain :
Genome accession: NC_010546
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 4370842 - 4373403 bp
Length : 2562 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGAGTCCCAATATAACGCAGCAGAGATCGAACAAAAATGGCAACAAGACTGGGTTAACCAGGGGTTAGACAAAACCCC
AGAAAACAGCGATAAACCCAAATTTTACGCCTTATCCATGTTTCCCTACCCATCTGGAAACCTACACATGGGCCATGTTC
GCAACTATGTTATTACAGATGTTATCGCCCGTCTCAAACGATTGCAAGGATACCGAGTTTTACATCCGATGGGGTGGGAT
GCGTTCGGACTTCCGGCGGAAAATGCAGCCATCGATCGCAATATTCCCCCCGCAGACTGGACTTATAAAAATATTGCCCA
AATGAAGCAACAACTGCAAACCTTGGGACTATCTATCGACTGGGATCGAGAAGTGGCCACCTGTTCCCCAGACTATTACA
AATGGACGCAATGGTTATTCTTGCAATTTTATCAAGCAGGGTTAGCTTATCAAAAAGAAGCAGCAGTCAACTGGGACCCC
ATCGATCAAACGGTGTTGGCCAATGAACAAGTGGACAGCGAGGGGTATTCCTGGCGATCGGGTGCTAAAGTAGAACGAAA
ACTGTTGCGTCAGTGGTTCTTTAAAATTACGGACTATGCAGAACAATTATTAACGGACTTGGATAAATTAACCGGATGGC
CCGACCGTGTTAAATTAATGCAGGAAAACTGGATCGGTAAGTCTGTCGGTGCATATTTGGAGTTTCCTGTCAAGGGCAGT
GAGGAAAAAATCGCCGTCTTTACCACCCGTCCGGATACGGTTTACGGGGTGACTTATGTGGTTTTGGCCCCTGAACACCC
TTTGACCCCCAAAGTGACTACAGAGGGGCAAAAAGAAGCCGTAGAAGCGTTTATTGAAGAGGTTTCCAACGAAAGCGAAA
TCGAACGCACAGCAGAAGATAAACCCAAACGAGGGATATTAACCGGAGGGACTGCTGTTAACCCCTTTAATGGTGAAGAA
ATCCCCATTTTGATTGCAGATTATGTATTGTATGAATATGGTACCGGTGCGGTGATGGGTGTACCGGCCCATGATACCCG
TGACTTTAAGTTTGCAACGGAGAAAGAGTTACCGATCAAAGTGGTGATCGTTCCTGAAAATTCCGAGGATAATAACCCTA
CGTTAACAGAAGCCTATACCGAACCAGGAATTATGGTCAATTCGGGTGAATTTAACGGAATGCAGTCCACTGAAGGCAAA
ACGGCTATTATTAACTATGCAGAGAAACAGGGTTACGGTAAAGCAAGGATACAGTATCGTCTGCGAGATTGGTTAATTTC
TCGGCAACGTTATTGGGGTTGTCCTATTCCAGTGGTGCATTGTCCCAGTTGCGGAACTGTGGCGGTTCCTGATGCAGATT
TACCTGTGAAATTGCCCGAAAATGTGGAATTTACGGGGCGTGGGGCTTCTCCTTTGGCAAAAATGGAAGATTGGATCAAC
GTTCCTTGTCCCAGTTGTGGGGAACCAGCAAAGCGTGAAACGGATACAATGGACACTTTTATTGACTCTTCTTGGTACTA
TTTACGTTACACGGATGCAATGAATGATCAAGAAGCATTTAAGTTAGAAAAAGCCAATGATTGGATGAATGTAGATCAAT
ACGTTGGTGGTATTGAACACGCGATTTTACACCTCTTATATTCTCGCTTTTTTACTAAAGTATTGCGAGACAGAGGTTTA
GTGAATGTGGATGAACCGTTTAAGCGTCTTTTGACACAGGGAATGGTACAAGCAATGGCCTATAAAAACCCCAAAACCGG
TAAGTATATTCCTGTGGATAAAGTGAACCCTGAAAGTCCCAAAGATCCGGATACAGGAGATGATTTAGAGGTGTTTTATG
AGAAGATGTCTAAGTCTAAATATAATGGAGTTGATCCGCAAAAAGTATTAGGAAAATATGGGGCAGATACGGCTAGAATG
TTCATTCTATTTAAAGCACCTCCTGAGAAAGATTTAGAATGGGATGATGCGGATGTAGAAGGACAATTTCGCTTTTTAAA
TCGGGTGTGGCGTTTGGTTAATGGCTATGAAAAAAAGCAAGGCGAAGTTATTAGTAACAAGGAGTTAAGCAAGGAAGAAA
AAGACTTAAGACGTGCCATCCATACTGCTATTAAAGAGATATCCGAAGACTTAGAAGGGGACTATCAATTTAATACGGCA
GTTTCTGAGTTAATGAAGTTAAGTAATGCGTTGAATGATGCTAAATGTATTAATTCTGAGGTTTATCAAGAAGGAATTGA
AACTTTATTGATTTTACTGGCACCCTTTGCTCCTCATATTGCTGAAGAATTATGGCATAATTTGGGACATGAAACTTCAA
TCCATTTAGAAACTTGGCCTCAGGTTGATCCCGATGCTTTAGTGGTAGATGAAATTACCCTAGTGATTCAAATTATGGGT
AAGACAAGGGGAACGATTCAAGTACCTGCTAATTCCAGTAAAGAGGAGTTAGAAAAATTAGCCCGTGAATCAGATATTGG
TCAACGTAACTTAGACGGAAAAGAGGTTAAAAAGGTGATTGTTGTTCCTGGAAAATTAGTTAACTTTGTGGTTCCTAAAT
AA

Protein sequence :
MESQYNAAEIEQKWQQDWVNQGLDKTPENSDKPKFYALSMFPYPSGNLHMGHVRNYVITDVIARLKRLQGYRVLHPMGWD
AFGLPAENAAIDRNIPPADWTYKNIAQMKQQLQTLGLSIDWDREVATCSPDYYKWTQWLFLQFYQAGLAYQKEAAVNWDP
IDQTVLANEQVDSEGYSWRSGAKVERKLLRQWFFKITDYAEQLLTDLDKLTGWPDRVKLMQENWIGKSVGAYLEFPVKGS
EEKIAVFTTRPDTVYGVTYVVLAPEHPLTPKVTTEGQKEAVEAFIEEVSNESEIERTAEDKPKRGILTGGTAVNPFNGEE
IPILIADYVLYEYGTGAVMGVPAHDTRDFKFATEKELPIKVVIVPENSEDNNPTLTEAYTEPGIMVNSGEFNGMQSTEGK
TAIINYAEKQGYGKARIQYRLRDWLISRQRYWGCPIPVVHCPSCGTVAVPDADLPVKLPENVEFTGRGASPLAKMEDWIN
VPCPSCGEPAKRETDTMDTFIDSSWYYLRYTDAMNDQEAFKLEKANDWMNVDQYVGGIEHAILHLLYSRFFTKVLRDRGL
VNVDEPFKRLLTQGMVQAMAYKNPKTGKYIPVDKVNPESPKDPDTGDDLEVFYEKMSKSKYNGVDPQKVLGKYGADTARM
FILFKAPPEKDLEWDDADVEGQFRFLNRVWRLVNGYEKKQGEVISNKELSKEEKDLRRAIHTAIKEISEDLEGDYQFNTA
VSELMKLSNALNDAKCINSEVYQEGIETLLILLAPFAPHIAEELWHNLGHETSIHLETWPQVDPDALVVDEITLVIQIMG
KTRGTIQVPANSSKEELEKLARESDIGQRNLDGKEVKKVIVVPGKLVNFVVPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-173 45