Gene Information

Name : guaA (cur_0401)
Accession : YP_001799795.1
Strain : Corynebacterium urealyticum DSM 7109
Genome accession: NC_010545
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 488025 - 489596 bp
Length : 1572 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGAATCACCAAAATCATCAGCCAGTCCTCGTGGTGGATTTCGGCGCGCAGTACGCACAGTTGATCGCGCGCCGCGTGCG
TGAGGCTCGGGTCTACTCCGAGGTCGTTCCGCACACCGCCACCATTGAAGAAATCAAGGCCAAGAACCCTGCGGCCATCG
TGCTGTCGGGTGGTCCGAGCTCGGTCTACGCCGATGGTGCACCGGCCCTGCGGCCGGAGCTGCTGGAGCTGGGCGTGCCG
GTGTTTGGCATTTGCTACGGCTTCCAGGCCATGACGCACGCGCTCGGCGGCACCGTTTCCGAGACGGGGCAGCGCGAGTA
CGGTCGCACCGAGGTCGAGATCCTCGATGACGGCGGCGTGCTGCACGCGGGCCTGGGCTCGCACAAGGCCTGGATGAGCC
ACGGCGATGCGGTCTCGCAGGCCCCGGAGGGCTTCACCGTTACCGCGAAGTCCGCCGGTGCGCCGGTCGCCGCCTTCGAG
TGCCTGGATCGCCGCATGGCCGGCGTGCAGTACCACCCGGAGGTCATGCACAGCCCGCACGGCCAGGAGGTGCTGGAGCG
CTTCCTCACGGAGGTCGCGGGCCTGGAGCAGAACTGGACCGCCTCCAACATCGCCGAGGAGCTCATCGAGCAGGTTCGGG
AGCAGATCGGTGAGGACGGCCGCGCCATCTGTGGCCTGTCCGGTGGCGTGGACTCCGCCGTGGCCGCTGCGATCGTGCAG
CGCGCCGTCGGCGACCGCCTGACCTGTGTGTTCGTGGACCACGGTCTGCTGCGCGCAGGGGAGCGCGAGCAGGTGGAGAA
CGACTTCGTCGCCGCGACCGGCGCGAAGCTGGTCACCGTGGATGAGCGCGAGGCCTTCCTCAAGCGCCTGGACGGCGTGA
CCGACCCGGAGGCCAAGCGCAAGGCCATCGGTGCGGAGTTCATCCGCTCCTTCGAGCGCGCCGTCGCTGGCGTGCTGGCC
GACTCCCCGGAGGGCTCCACCGTGGACTTCCTGGTCCAGGGCACCCTGTACCCGGACGTCGTCGAGTCCGGCGGCGGCTC
CGGCACCGCGAACATCAAGAGCCACCACAACGTCGGTGGCCTGCCGGATGACGTCGAGTTCAAGCTGGTCGAGCCGTTGC
GCCAGCTGTTTAAGGACGAGGTCCGCGCGGTGGGCCGCGAGCTCGGCCTGCCGGAGATTATCGTCGCCCGTCAGCCGTTC
CCGGGCCCGGGCCTGGGCATCCGCATCATCGGCGCGGTCAACGAGGAGCGACTGGAGACGCTGCGCGCGGCGGACAAGAT
CGCCCGCGAGGAGCTCAGCGCCGCTGGCCTGGACGGCGAGATCTGGCAGTGCCCGGTCGTCCTGCTCGCGGACGTGCGCT
CCGTGGGTGTGCAGGGCGACGGCCGTACTTACGGTCACCCGATCGTGCTGCGCCCGGTCTCCAGTGAGGACGCCATGACC
GCCGATTGGTCTCGCATCCCTTATGACGTGCTGGAGAAGGTCTCCACCCGCATCACCAACGAGGTGGCGGAGGTTAACCG
CGTGGTGCTGGACATCACCAGCAAGCCGCCGGGAACCATCGAATGGGAGTAA

Protein sequence :
MNHQNHQPVLVVDFGAQYAQLIARRVREARVYSEVVPHTATIEEIKAKNPAAIVLSGGPSSVYADGAPALRPELLELGVP
VFGICYGFQAMTHALGGTVSETGQREYGRTEVEILDDGGVLHAGLGSHKAWMSHGDAVSQAPEGFTVTAKSAGAPVAAFE
CLDRRMAGVQYHPEVMHSPHGQEVLERFLTEVAGLEQNWTASNIAEELIEQVREQIGEDGRAICGLSGGVDSAVAAAIVQ
RAVGDRLTCVFVDHGLLRAGEREQVENDFVAATGAKLVTVDEREAFLKRLDGVTDPEAKRKAIGAEFIRSFERAVAGVLA
DSPEGSTVDFLVQGTLYPDVVESGGGSGTANIKSHHNVGGLPDDVEFKLVEPLRQLFKDEVRAVGRELGLPEIIVARQPF
PGPGLGIRIIGAVNEERLETLRAADKIAREELSAAGLDGEIWQCPVVLLADVRSVGVQGDGRTYGHPIVLRPVSSEDAMT
ADWSRIPYDVLEKVSTRITNEVAEVNRVVLDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 87
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-130 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-131 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-131 51