Gene Information

Name : smpB (cur_1500)
Accession : YP_001800894.1
Strain : Corynebacterium urealyticum DSM 7109
Genome accession: NC_010545
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1751580 - 1752116 bp
Length : 537 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCTAAGAAGAGCACCCCGGTGGATTCCGGGAGATCGAAGGGGAAGAAGGCCTCCGCACCACGTGGCGGGGGCCCGGC
CGTCATTGCCACCAACCGCAAGGCGCGCCACGACTACCACATCCTCGACACCTACGAGTGCGGCGTGGTTCTCGTCGGCA
CAGAGGTCAAGGCCCTGCGGGAGGGCAAGGCCAGCCTCGTGGATGCTTATGCCACTATCGATGCCGGAGAGGTATGGCTG
CGGGGACTGCATATCCCGGAGTACTCCCGCGGCAACTTCTGGAACCACACCCCGCGACGCGTGCGTAAGCTGCTGCTGCA
CCGCCGCGAGATTGATTCGCTGACGGGCAAAGTGCGCGACGGCAACCACACGCTTGTTCCGTTGCAGCTGTACTTCGTCG
ATGGGCGCTTGAAGTGCGAGCTGGCCCTGGCCCGCGGTAAGCAGGACTACGACAAGCGCCAGGACATCAAGCGCCGCACC
GAGGAGCGCGAAGTGGTCCGCGAGCTGGGGCGCAAGATCAAGGGGATGAAGGGCTAG

Protein sequence :
MAKKSTPVDSGRSKGKKASAPRGGGPAVIATNRKARHDYHILDTYECGVVLVGTEVKALREGKASLVDAYATIDAGEVWL
RGLHIPEYSRGNFWNHTPRRVRKLLLHRREIDSLTGKVRDGNHTLVPLQLYFVDGRLKCELALARGKQDYDKRQDIKRRT
EEREVVRELGRKIKGMKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-74 100
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-27 53
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-21 41