Gene Information

Name : cur_1103 (cur_1103)
Accession : YP_001800497.1
Strain : Corynebacterium urealyticum DSM 7109
Genome accession: NC_010545
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 1308946 - 1310766 bp
Length : 1821 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAGCGCGCAAAACGCAGATATTTACGCGTCCGAAATTCACCCAAAGCACCGTTACGAACCCCTGCGGGTCAACGGTCT
CGAGGTGCCGCAGACCGCGATCGACCTGGACGATTCCCCCACTGGACCGAACGAGCCGGTGAAGATCTACCGCACCCGCG
GTCCCTACGCGGAGCCGGAGGTGGGCCTGCCCGCGCTGCGCAGCGAGTGGATCCAGGAACGCGGTGACGTCGAGGAATAC
GAGGGCCGGAAGCGCAACCTGCTGGACGACGGCACCCGGGCCGCCAAGCGCGGCGCAGCCAGCGAAGAATGGCGTGGCGA
GAAGCGCGCACCACTTCGAGCGAAGCAGGGGCAGCGCGTGACGCAGATGGCTTATGCCCGCCGCGGGGAGGTCACCCGCG
AGATGGAGTTCGTCGCACTGCGCGAGAACTGCGACGTCGAGAAGGTACGCGCGGCGGTGGCCTCCGGCCGGGCGATCATC
CCGAACAACGTCAACCACCCGGAATCCGAGCCGATGATCATCGGTAACCAGTTCCTCACCAAGATCAACGCCAACATCGG
CAACTCCGCGGTGACCAGCTCCATCCGCGAGGAAGTGGACAAGCTGCGCTGGGCGACCCGTTGGGGCGCGGACACCGTCA
TGGACCTGTCCACCGGTAACGACATCCACACCACCCGCGAATGGATCCTGCGCAACTCCCCTGTTCCGATCGGCACCGTT
CCGATCTACCAGGCACTGGAGAAGGTGGGTGGCGTGGCCGAGGACCTGACCTGGGAGATCTTCCGCGACACGGTCATCGA
GCAGGCCGAGCAGGGCGTGGACTACATGACCGTGCATGCAGGCGTGCGCTTGCCGTTTGTGCCGCTGACATCCAAGCGTG
TCACCGGCATCGTCTCCCGCGGCGGGTCGATCATGGCGGGCTGGTGCTTGGCCCACCACAAGGAGTCCTTCCTCTACGAG
AACTTCGATGAGCTGTGCGAAATCTTCGCGGCCTACGACGTCGCGTTCTCCCTGGGTGACGGTCTGCGGCCAGGCTCCAT
CGCCGACGCCAACGACACCGCCCAGTTCGCGGAGCTGAAGACCATCGGCGAACTGTGCAAGCGCGCCTGGGATTACGACG
TCCAGGTCATGATCGAAGGCCCGGGACATGTGCCGCTGAACAAGATCCAGATCAACAACGAGAAGGAAGAGGAATGGTGC
GGGGGCGCGCCGTTCTATACCCTTGGGCCGCTGGTCACGGATATCGCACCGGGTTATGACCACATCACCTCCGCAATCGG
CGCGGCGAACATCGCTGCCGGTGGCACCGCGATGCTGTGCTACGTCACCCCGAAGGAGCACCTGGGGCTGCCGAATAAGG
ACGACGTGAAGACCGGCGTGATCACCTACAAGCTCGCCGCGCACGCCGCAGACGTGGCCAAGGGCCATCCCGGCGCCCAC
GAGTGGGACGATGCCATGAGTAAGGCCCGCTTCGAGTTCCGCTGGCACGACCAGTTCGCGCTCTCGCTGGACCCCGACAC
CGCGCAGGCGTACCACGACGAGACGCTGCCGGCTGAGCCCGCGAAGACCGCTCACTTCTGTTCGATGTGTGGCCCGAAGT
TCTGCTCGATGCGCATCAGCCAGGACATTCGCGACGAATTCGGCGACAAGATGGCCGCAGACCTGGGGCTACCAAGCATC
GGCCAGCCCGAGGACGCAGCACATGCCGACGCGGACGTCCTCGCGGCAGTCGAGGCTGGCATGGACGAAAAGTCCGCTGA
GTTCCTGGAACGTGGCGGGCAGATCTACTTGGAGGATGATGCGAGTGTGCAACACAGTTGA

Protein sequence :
MSAQNADIYASEIHPKHRYEPLRVNGLEVPQTAIDLDDSPTGPNEPVKIYRTRGPYAEPEVGLPALRSEWIQERGDVEEY
EGRKRNLLDDGTRAAKRGAASEEWRGEKRAPLRAKQGQRVTQMAYARRGEVTREMEFVALRENCDVEKVRAAVASGRAII
PNNVNHPESEPMIIGNQFLTKINANIGNSAVTSSIREEVDKLRWATRWGADTVMDLSTGNDIHTTREWILRNSPVPIGTV
PIYQALEKVGGVAEDLTWEIFRDTVIEQAEQGVDYMTVHAGVRLPFVPLTSKRVTGIVSRGGSIMAGWCLAHHKESFLYE
NFDELCEIFAAYDVAFSLGDGLRPGSIADANDTAQFAELKTIGELCKRAWDYDVQVMIEGPGHVPLNKIQINNEKEEEWC
GGAPFYTLGPLVTDIAPGYDHITSAIGAANIAAGGTAMLCYVTPKEHLGLPNKDDVKTGVITYKLAAHAADVAKGHPGAH
EWDDAMSKARFEFRWHDQFALSLDPDTAQAYHDETLPAEPAKTAHFCSMCGPKFCSMRISQDIRDEFGDKMAADLGLPSI
GQPEDAAHADADVLAAVEAGMDEKSAEFLERGGQIYLEDDASVQHS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 9e-161 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 9e-161 63
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 3e-153 59