Gene Information

Name : thyA (PAa_0084)
Accession : YP_001798767.1
Strain : Candidatus Phytoplasma australiense
Genome accession: NC_010544
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 92493 - 93359 bp
Length : 867 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAAACTTATTTAGATTTATGTCGTTTTATTTTAAAAAAAGGTTTTAATAAAGAAGACCGAACGAAAACAGGAACTAA
AAGCGTTTTTGGTTATCAAATGCGTTTCAATCTCCAAGATGGCTTCCCCTTGCTAACTACTAAAAAAATGTATTTCAAAG
CGATTATTCATGAACTTTTATGGTTTTTAAAAGGAGACACGAACATTTCTTATTTAGTCAAAAACAATGTTAATATTTGG
AATGATTGGCCTTATCAAAAATATCAAAAATCGCCTCATTTTAAAAACGAAACTATGGAAGAATTTATTCAAAAAATTAA
AAAAGATAAAGCTTTTGCTGGTTTGCATGGAAATTTAGGTCCTGTTTATGGCAAACAATGGCGTGATTTTAATGGCTTTG
ATCAAATTAAATTTTTAATTTCTGAAATAAAAAATAATCCAGATTCTAGGCGTTTGATTTTGAGTTCTTGGAATCCAGAA
CAATTACATCAAATGGTTTTACCTCCTTGTCATATTTTAATGCAATTTTATGTTTTAGAAGGAAAACTTTCCTTGCAACT
TTATCAAAGGAGTGGCGATGTTTTTTTAGGAGTACCTTTTAATATTGCTTCTTATGCTTTGTTGCTTTTGATGGTTGCTC
AAGTGACAAATTTAGAAGTTGGCGAATTTATTCATACTTTGGGAGACGCACATATTTATCACAACCATTTAAATCAAATC
AAAATTCAAATCCAAAGAACTCCAAAAAAACTTCCCCAAATGATTTTAAACCCTCATATTAAAGATATTGATGGCTTTTC
ATTTGAAGATTTTACTTTAAAAAATTATTTTTGCGATGGAACTTTGAAAGGAGATATTGCTATATGA

Protein sequence :
MKTYLDLCRFILKKGFNKEDRTKTGTKSVFGYQMRFNLQDGFPLLTTKKMYFKAIIHELLWFLKGDTNISYLVKNNVNIW
NDWPYQKYQKSPHFKNETMEEFIQKIKKDKAFAGLHGNLGPVYGKQWRDFNGFDQIKFLISEIKNNPDSRRLILSSWNPE
QLHQMVLPPCHILMQFYVLEGKLSLQLYQRSGDVFLGVPFNIASYALLLLMVAQVTNLEVGEFIHTLGDAHIYHNHLNQI
KIQIQRTPKKLPQMILNPHIKDIDGFSFEDFTLKNYFCDGTLKGDIAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 5e-68 52
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-55 47