Gene Information

Name : guaA (Pnec_0530)
Accession : YP_001797407.1
Strain : Polynucleobacter necessarius STIR1
Genome accession: NC_010531
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 476903 - 478510 bp
Length : 1608 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGCACGACAAAATACTGATTCTTGATTTTGGTTCGCAAGTAACTCAACTCATTGCTCGCCGCGTGCGTGATGGGCGCGT
GTACTCAGAGATCCATCCGTATGATTGTGATCCGGAGCTTATTCGCAAGTTCATTCAAGAGCAGGGTGGTAAAGGCATCA
TCCTTTCTGGTGGTCCGAGTTCTGTAACTGAAGAAGGTAGTCCTCGTGCGCCACAAATTGTTTTTGAACTTGGCGTTCCA
GTTTTGGGTATTTGTTACGGCATGCAAACCATGGCTACCCAGTTAGGTGGGGCCGTCGCTTCTGCTGAGTCCTTGGGTAA
GGCCCGTGAGTTTGGGTATTCAGAAGTGCGCGCCCATGGTCACACGAATTTGCTTAAAGGCATTCAGGACTTTTCTACCA
GTGAAGGCCATGGCATTTTGAAGGTGTGGATGAGTCATGGCGACTCCGTAACTACATTGCCGTCATCATTCAAATTGATG
GCCTCGACTGAGTCTTGCCCTATTGCAGGTATGGCTGATGAAGAGCGTAGTTTCTATGCATTCCAGTTTCACCCTGAAGT
AACACATACCATTCAAGGCACCGCAATCATTGAGCGCTTTGTACATGAGATTTGCAAGTGCAAGCCTGATTGGGTAATGG
GTGATTACATCGCAGAGGCTGTAGAAAATATTCGCAAACAAGTTGGCGACGAAGAGGTAATTCTCGGTTTATCGGGTGGT
GTTGATTCTAGTGTTGCAGCTGCCTTGATTCATCGAGCGATTGGCGATCAACTCACTTGTGTGTTTGTTGATCATGGCTT
GCTTCGTCTTAATGAAGGCGATATGGTGATGGAAATGTTCGCACGCAATTTAGGTGTGAAAGTCATTCGTGTCGATGCTA
AAGAAACTTTTATGGGTGAGTTAGCCGGCGTTTCTGACCCAGAAGCAAAGCGAAAAATTATCGGTAAAGAATTCGTTGAA
ATTTTCCAAGCTGAATCTGGAAAAATCAAAAATGCTAAGTGGCTTGCACAGGGAACCATCTATCCAGACGTGATTGAGTC
TGCTGGTAAGGGCAAGAAGGGCGCGCATACCATTAAGAGTCATCATAACGTTGGTGGCTTGCCAGAAGATATGCATCTCA
AGCTGCTTGAGCCATTGCGTGAACTTTTTAAAGATGAAGTGCGCGAACTCGGCGTAGCACTTGGATTGCCTCGTGAGATG
GTGTATCGCCATCCATTCCCGGGCCCGGGTTTAGGTGTTCGTATCTTAGGTGAAGTGAAGGCAGAGTTTGCAAGCTTGTT
GCAGCGTGCCGATGCTATCTTCATTGAGGAGTTACGCAATACGATTGATGAAGTTAGCCAGAAGTCTTGGTATGACTTAA
CTAGCCAAGCCTTTGCTGTATTCCTGCCAGTCAAGTCTGTTGGTGTGATGGGTGACGGCAGAACATATGAGTACGTCGTT
GCTTTACGAGCAGTGCAAACTCAAGACTTTATGACGGCACACTGGGCACATCTACCGCATGAATTGCTAGGTAAGGTATT
CAACCGAATCATTAACGAAGTGCGTGGCATTAATCGAGTGGTATACGACATTAGCGGAAAGCCGCCAGCAACGATCGAGT
GGGAATAA

Protein sequence :
MHDKILILDFGSQVTQLIARRVRDGRVYSEIHPYDCDPELIRKFIQEQGGKGIILSGGPSSVTEEGSPRAPQIVFELGVP
VLGICYGMQTMATQLGGAVASAESLGKAREFGYSEVRAHGHTNLLKGIQDFSTSEGHGILKVWMSHGDSVTTLPSSFKLM
ASTESCPIAGMADEERSFYAFQFHPEVTHTIQGTAIIERFVHEICKCKPDWVMGDYIAEAVENIRKQVGDEEVILGLSGG
VDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGDMVMEMFARNLGVKVIRVDAKETFMGELAGVSDPEAKRKIIGKEFVE
IFQAESGKIKNAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPEDMHLKLLEPLRELFKDEVRELGVALGLPREM
VYRHPFPGPGLGVRILGEVKAEFASLLQRADAIFIEELRNTIDEVSQKSWYDLTSQAFAVFLPVKSVGVMGDGRTYEYVV
ALRAVQTQDFMTAHWAHLPHELLGKVFNRIINEVRGINRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-124 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-124 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-124 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-110 47