Gene Information

Name : Pnec_1159 (Pnec_1159)
Accession : YP_001797932.1
Strain : Polynucleobacter necessarius STIR1
Genome accession: NC_010531
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1003613 - 1004923 bp
Length : 1311 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATTGATCCGCAATTACTCCGTAAAGATATCGCCGCAGTTGCTGCACGCCTAGCTACTCGCAAATTCCAATTGGATGT
TGAGAAATTCAACGCCCTAGAATCGGAGCGAAAATCTCTACAAACCCGTACTGAAGAACTGCAGGCCAAACGTAATCAAT
TGTCTAAAGCGATTGGTATGAAAAAAGGTAAGGGCGAAGGCGCCGCTGCTGAGATGGCTGAGGTTACGCAAGTTAACGCA
GACATGGAATCTGGTTCATCACGCTTAGCAGTATTGCAGGCTGAGATTTCTGATTTCTTGATGGGTATTCCGAATCTCCC
GGATGAGTCTGTACCTGCCAGTAAAGATGAAACAGAAAATAAAGAAGTGAAACGCTGGGGCGAGCAGCCTATTTTTGATT
TTGAGGTTAAAGATCATGTTGACCTTGGTGGTCCATTGGGCTTGGATTTTGAAGTGGCAGCCAAGATCAGTGGTTCCCGC
TTTATCGTACTCAAGGGGCCGATTGCAAGATTGCATCGTGCCTTAGCGCAATTCATGATTGATACGCACGCTACTGAGCA
TCAGTACCAAGAAGTTTATGCGCCTTATATGGTGAATGCTGCATCAATGCGCGGTACTGGTCAGTTACCCAAGTTTGAAG
AGGACTTATTCAAAGTTCCGCGTCAAATGGGTGGCGAGGATGGTAATGGAGAGGCCAAAACTGAAAACTTTTACCTTATT
CCAACAGCTGAAGTTCCTGTTACCAATCTAGTTCGAGATGAAATTGTGAACACCGACAATCTGCCAATGAAGTTTGTCGC
TCACACACCTTGCTTTCGATCAGAGGCAGGTAGCTATGGTCGTGACGTACGCGGCATGATTCGTCAGCATCAGTTTGACA
AAGTAGAGTTGGTGCAAATTACTAAGCCAGAAGATTCAATGCAGGCTTTGGAGGATCTCACAGGCCATGCAGAAAGAATC
CTAGAGCTTTTAGAGCTGCCTTATAGAAAAGTATTGCTCTGTACTGGCGACATGGGCTTTGGTAGCACTAAGACTTATGA
CCTAGAAGTTTGGGTGCCGTCACAAAATGCCTATAGAGAAATTAGTTCATGCTCTAGCATGGGCGATTTCCAGGCAAGAC
GTATGCAAGCTAGATTTAAAGTGGGTCAAGGCAAGCCTGAACTGGTTCATACTTTAAATGGTTCAGGCCTAGCCGTAGGC
AGGGCGTTAGTTGCATTGTTAGAGAATAAGCAACAGGTTGATGGCAGCATTGCTATTCCTAAAGCACTGCAACCCTACTT
GGGTGGTTTAGAAGTTCTCAAGCCAATTTAA

Protein sequence :
MIDPQLLRKDIAAVAARLATRKFQLDVEKFNALESERKSLQTRTEELQAKRNQLSKAIGMKKGKGEGAAAEMAEVTQVNA
DMESGSSRLAVLQAEISDFLMGIPNLPDESVPASKDETENKEVKRWGEQPIFDFEVKDHVDLGGPLGLDFEVAAKISGSR
FIVLKGPIARLHRALAQFMIDTHATEHQYQEVYAPYMVNAASMRGTGQLPKFEEDLFKVPRQMGGEDGNGEAKTENFYLI
PTAEVPVTNLVRDEIVNTDNLPMKFVAHTPCFRSEAGSYGRDVRGMIRQHQFDKVELVQITKPEDSMQALEDLTGHAERI
LELLELPYRKVLLCTGDMGFGSTKTYDLEVWVPSQNAYREISSCSSMGDFQARRMQARFKVGQGKPELVHTLNGSGLAVG
RALVALLENKQQVDGSIAIPKALQPYLGGLEVLKPI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-90 50