Gene Information

Name : Pnec_1042 (Pnec_1042)
Accession : YP_001797831.1
Strain : Polynucleobacter necessarius STIR1
Genome accession: NC_010531
Putative virulence/resistance : Resistance
Product : O-succinylhomoserine sulfhydrylase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 904716 - 905924 bp
Length : 1209 bp
Strand : -
Note : catalyzes the conversion of O-succinylhomoserine into homocysteine

DNA sequence :
ATGAAGAGTAAAACTACACGCAAAAAACTGGATTTTTCTAAACTTGCACTCGAAACCATAGCAGTTCGTGTAGGCACTCG
TCGTACGGCTGAATATCAAGAGCACTCCGAGGCAATGTTCCTCACATCAAGCTTTTGCTTTGATAGCGCCGAATTAGCGG
CTGATGGCTTTGCTCATGCTGATCAAGGTTTTATTTATTCACGCTTTACCAATCCAACCGTGAGTATGTTCCAAGATCGC
TTGGCTGCTCTTGAGGGTGGCGAAGCTTGTATTGCTACTGCCTCTGGTATGTCTGCCATTCTGACAATGGCAATGGCTCA
CCTGCAAGCAGGTGATCACGTTATTTGCTCGCGTTCTGTATTTGGTGCAACGATTCAGTTGTTCACGAATATTTTGGGTC
GCTTTGGTATTACGACAACTTATGTTGATTTGACTGATACTAAGTCATGGCAGGCTGCTGTCCAACCAAACACCAAACTC
TTTTATCTAGAGACACCTTCCAATCCTTTGACTGAGATTGCGGATATCAAAGCAATTTCAAGGATAGCAAAAAAGGCAGG
TGCCTTGTTTGCTGTAGATAACTGCTTCTGCACTCCGGCATTACAAAAACCATTGGCGCTTGGTGCTGATGTTGTGATTC
ATTCTGCAACTAAGTATTTAGATGGTCAGGGCAGGATGGTTGGTGGCGCCATTGTAGGCAACAAAGATTTCATTATGGGA
AAAGTGTTCCCTTATGTGCGTACTGCAGGCCCAACACTGTCAGCATTCAATGCTTGGGTATTCTTAAAAGGCTTGGAGAC
TCTAGAGCTTCGCATGAAGCAGCAGAGTCAAAATGCGCTTGCCTTGGCTCAATGGTTGGAGAAGCAACCTGGCGTAGAAC
GCGTGTACCATCCAGGCCTGAAAACGCACCCTCAACATGCCTTAGCTAAACGCCAGCAAAAAGAGGGTGGGGCGATTCTA
TCTTTTACCCTCAAGGGTGGAAAGAAGGCGGCATTCAAACTTATCAATCAAACCAAGCTCTGCTCGATCACTGCAAACTT
AGGGGATACCCGCACAACAATTACCCATCCAGCGACAACGACACATTGTCGCGTCAGTCCTGAAGCCAGAAAAGCAGCAG
GCATATCCGATGGATTGGTGCGTATTGCAGTTGGCCTCGAGAATATCAGCGATTTAAAGAACGACCTCCTTGGTGGACTC
AAAAAATAA

Protein sequence :
MKSKTTRKKLDFSKLALETIAVRVGTRRTAEYQEHSEAMFLTSSFCFDSAELAADGFAHADQGFIYSRFTNPTVSMFQDR
LAALEGGEACIATASGMSAILTMAMAHLQAGDHVICSRSVFGATIQLFTNILGRFGITTTYVDLTDTKSWQAAVQPNTKL
FYLETPSNPLTEIADIKAISRIAKKAGALFAVDNCFCTPALQKPLALGADVVIHSATKYLDGQGRMVGGAIVGNKDFIMG
KVFPYVRTAGPTLSAFNAWVFLKGLETLELRMKQQSQNALALAQWLEKQPGVERVYHPGLKTHPQHALAKRQQKEGGAIL
SFTLKGGKKAAFKLINQTKLCSITANLGDTRTTITHPATTTHCRVSPEARKAAGISDGLVRIAVGLENISDLKNDLLGGL
KK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 8e-50 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Pnec_1042 YP_001797831.1 O-succinylhomoserine sulfhydrylase BAC0207 Protein 6e-61 41