Gene Information

Name : macB (RALTA_B1841)
Accession : YP_002008476.1
Strain :
Genome accession: NC_010530
Putative virulence/resistance : Resistance
Product : macrolide-specific ABC-type efflux ABC transporter ATP-binding domain (modular protein)
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : -
Position : 1992590 - 1993282 bp
Length : 693 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11544226; Product type t : transporter

DNA sequence : 
ATGAGCACGGCGCCGCTGGTGCAGATCGCGCACGTCGCCAAGTCGTACCGGCGCGGCGTGCAGACGGTGCCGGTGCTGAC
CGATATCTCGCTGGAGATCGGCGAAGGCGATTTCGTCGCGCTGATGGGCCCCTCCGGCTCGGGCAAGAGCACGCTGCTGA
ACCTGATTGCCGGCATCGACCGGCCCGACAGCGGCACGCTGCGCGTCGCCGGGCTGGACATCACGCAGCTGCCGGAAGCG
GCGCTGGCCGACTGGCGCGCCGCCAATGTCGGCTTTATCTTCCAGTTCTACAACCTGATGCCGGTGCTGACCGCGTTCGA
GAACGTCGAGCTGCCGCTGATGCTGACGCGCCTGCCGCGGGCGGAGCGGCGCGCGCGCGTGGAACTGGTGCTGGACATGG
TCAACCTGGCCGACCGCATGAGCCACTATCCGTCGGAGCTGTCGGGCGGCCAGCAGCAGCGCGTGGCGATCGCGCGCGCG
CTGATCACCGACCCCGCGCTGATCGTCGCCGACGAGCCCACCGGCGACCTCGACCGCACCTCGGCGGCCGAGATCCTGGC
GATGCTGCAGCGGCTCAACGCTGATGCCGGCAAAACCATCATCATGGTCACGCACGATGCGCACGCCGCCGCCGCGGCCG
GCTCGCTGGTCCACCTGGAGAAGGGGGAGCTGATCCGTGGCGAGCCGGCGTAG

Protein sequence : 
MSTAPLVQIAHVAKSYRRGVQTVPVLTDISLEIGEGDFVALMGPSGSGKSTLLNLIAGIDRPDSGTLRVAGLDITQLPEA
ALADWRAANVGFIFQFYNLMPVLTAFENVELPLMLTRLPRAERRARVELVLDMVNLADRMSHYPSELSGGQQQRVAIARA
LITDPALIVADEPTGDLDRTSAAEILAMLQRLNADAGKTIIMVTHDAHAAAAAGSLVHLEKGELIRGEPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Cp1002_1464 YP_005681730.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 5e-33 44
CpC231_1466 YP_005683828.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-33 43
cpfrc_01473 YP_003783873.1 hypothetical protein Not tested PiCp 5 Protein 3e-33 43
CpI19_1473 YP_005685914.1 ABC transporter ATP-binding protein Not tested PiCp 5 Protein 3e-33 43
cur_1502 YP_001800896.1 cell division ATP-binding protein FtsE Not tested Not named Protein 6e-36 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
macB YP_002008476.1 macrolide-specific ABC-type efflux ABC transporter ATP-binding domain (modular protein) NC_008702.1.4606598. Protein 2e-40 52
macB YP_002008476.1 macrolide-specific ABC-type efflux ABC transporter ATP-binding domain (modular protein) NC_012469.1.7686878. Protein 5e-45 50
macB YP_002008476.1 macrolide-specific ABC-type efflux ABC transporter ATP-binding domain (modular protein) CP001581.1.gene798.p Protein 2e-38 43