Gene Information

Name : guaA (RALTA_A1664)
Accession : YP_002005672.1
Strain :
Genome accession: NC_010528
Putative virulence/resistance : Unknown
Product : gmp synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1752841 - 1754460 bp
Length : 1620 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCACGACAAAATCCTCATTCTTGATTTCGGCTCGCAGGTCACGCAACTGATCGCGCGGCGCGTCCGCGAGGCGCACGT
CTATTGCGAAATCCATCCGAACGACGTCAGCGACGCGTTCGTGCGCGAATTCGCTCCCAAGGCGATCATCCTGTCCGGCA
GCCACGCCAGCACCTATGAAGACCACCAGCTGCGCGCGCCGCAGGCGGTGTGGGACCTGGGCGTGCCGGTGCTGGGCATC
TGCTACGGCATGCAGACCATGGCGGTGCAGCTGGGCGGCAAGGTCGAGTGGAGCGACCATCGCGAATTCGGCTACGCCGA
GATGCGCGCCCACGGCCATACCGAGCTGCTCAAGGACATCGAGGACTTCCGCACGCCGGAAGGCCACGGCATGCTCAAGG
TGTGGATGAGCCATGGCGACAAGGTCACCGGCCTGCCGCCCGGCTTCAAGCTGATGGCCTCCACGCCGAGCTGCCCGATC
GCCGGCATGGCCGACGAGACGCGCCACTACTACGCCGTGCAGTTCCACCCCGAGGTCACGCACACCGTCAAGGGCCGCCA
GATGCTGGAGCGCTTCGTGCTGCAGATCGCCGGCTGCAAGCCTGACTGGGTCATGCGCGACCATATCGAGGAAGCGGTCG
CCAAGATCCGCGAGCAGGTCGGCGATGAGGAAGTCATCCTGGGCCTGTCCGGCGGCGTCGATTCGTCGGTGGCCGCGGCG
CTGATTCATCGCGCCATCGGCGACCAGCTCACCTGCGTGTTCGTCGACCACGGCCTGCTGCGCCAGGACGAAGGCAAGCT
GGTGATGGAAATGTTCGTCGGCCGCCTGCACGCCAAGGTGGTCCATGTCGACGCCTCCGAGCAGTTCCTCGGCCACCTGG
CCGGCGTGACCGACCCCGAGCAGAAGCGCAAGATCATCGGCCGCGAATTCGTCGAGGTGTTCCAGGCCGAGGCCCGCAAG
CTGACCAACGCCAAGTGGCTGGCGCAGGGCACCATCTACCCGGACGTGGTCGAGTCGGGGGGCACCAAGACCAAGAAGGC
CACCACCATCAAGAGCCACCACAACGTCGGCGGCCTGCCCGAGACGCTGGGCCTGAAACTGCTCGAACCGCTGCGCGACC
TGTTCAAGGACGAAGTGCGCGAGCTGGGCGTGGAGCTGGGCCTGCCGCCCGAGATGGTCTACCGCCACCCGTTCCCGGGC
CCGGGCCTGGGCGTGCGCATCCTTGGCGAAGTCAAGCGCGACTACGCCGACCTGCTGCGCCGCGCCGATGCCATCTTCAT
CGAAGAACTGCGCAAGACCATCGCCACCGAGCACGACGCCGCCGCGGGCCTGTGCGAACCCGAACAGGTCGGCAAGAGCT
GGTACGACCTGACCAGCCAGGCCTTCGCCGTGTTCCTGCCGGTCAAGTCCGTCGGCGTGATGGGCGACGGCCGCACCTAC
GACTACGTCGTCGCGCTGCGCGCGGTGCAGACAACCGACTTCATGACCGCGCACTGGGCGCACCTGCCGTATGCGCTGCT
GGGCCGCTGCTCGAACCGCATCATCAACGAAGTCCGGGGTTTGAACCGGGTCGTGTATGACGTGTCGGGGAAGCCGCCGG
CGACGATCGAGTGGGAGTGA

Protein sequence :
MHDKILILDFGSQVTQLIARRVREAHVYCEIHPNDVSDAFVREFAPKAIILSGSHASTYEDHQLRAPQAVWDLGVPVLGI
CYGMQTMAVQLGGKVEWSDHREFGYAEMRAHGHTELLKDIEDFRTPEGHGMLKVWMSHGDKVTGLPPGFKLMASTPSCPI
AGMADETRHYYAVQFHPEVTHTVKGRQMLERFVLQIAGCKPDWVMRDHIEEAVAKIREQVGDEEVILGLSGGVDSSVAAA
LIHRAIGDQLTCVFVDHGLLRQDEGKLVMEMFVGRLHAKVVHVDASEQFLGHLAGVTDPEQKRKIIGREFVEVFQAEARK
LTNAKWLAQGTIYPDVVESGGTKTKKATTIKSHHNVGGLPETLGLKLLEPLRDLFKDEVRELGVELGLPPEMVYRHPFPG
PGLGVRILGEVKRDYADLLRRADAIFIEELRKTIATEHDAAAGLCEPEQVGKSWYDLTSQAFAVFLPVKSVGVMGDGRTY
DYVVALRAVQTTDFMTAHWAHLPYALLGRCSNRIINEVRGLNRVVYDVSGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-120 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-120 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-120 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-107 48