Gene Information

Name : Lcho_4084 (Lcho_4084)
Accession : YP_001793101.1
Strain : Leptothrix cholodnii SP-6
Genome accession: NC_010524
Putative virulence/resistance : Virulence
Product : type VI secretion ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 4577943 - 4580693 bp
Length : 2751 bp
Strand : -
Note : KEGG: azo:azo3903 putative ATP-dependent Clp protease, ATP-binding subunit ClpB; TIGRFAM: type VI secretion ATPase, ClpV1 family; PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase AAA-2 domain protein; SMART: AAA ATPase

DNA sequence :
ATGACCGAGATCTCCCGCACGGCCCTGTTCGGCAAGCTCGACCCGCTGGCCTACAAGGCGATCGAAGGCGCCACGGTGTT
CTGCAAGATGCGCGGCAATCCCTACGTCGAGCTGCAGCACTGGCTGGCGCAGATCCTCAACACGCCCGATTCCGACCTGC
ACCGCATCATTCGCCACTACGAGCTCGACAGCGCCGCGCTCGCCGCCGACCTGACGCGCTCGCTCGACCGCCTGCCGCGC
GGCGCCTCGTCGATCTCGGACTTCTCGACCTTCGTGCTCGATGCGGTCGAGCGGGCCTGGATCTACGGCTCGCTGATGTT
CGGCGAACGCCAGATCCGCACCGGCCACCTGCTGATCGGGCTGCTCAAGACGCCGTCGCTGCGCAACGTGCTGCTGTCGA
TCTCGAAGCAGTTCGAGCGCGTCAAGCTCGATGACCTGGCCGACCGATTCGCCAGCCTGCTGGCGGCGTCGCCCGAGCAG
TCGCAAGGCGCCAGCGACAGCGGTGCCGCACCCGGCGAGGCCAGCGACGCGATCCCGCCCGCGGCGATGGGCAAGCAGGA
GGCGCTCAAGCGCTTCACCACCGACCTCACCGAGCAGGCGCGCGCCGGCAAGATGGACCCGATCGTCGGCCGCGACGACG
AGATCCGCCAGGTGGTCGACATCCTGATGCGCAGGCGCCAGAACAACCCGATCCTGGTCGGCGAGGCCGGTGTCGGCAAG
ACCGCGGTGGTGGAAGGTTTCGCCCAGCGCATCGCCCGCGGCGACGTGCCGCCGGCGCTGAAGGAGGTGCAGCTGCTCGC
GCTCGACGTCGGCCTGCTGCAGGCGGGGGCGAGCATGAAGGGCGAGTTCGAGCAGCGCCTGCGTTCGGTGATCGAGGAGG
TGCAGGCGAGCCCGAAGCCGATCATCCTGTTCGTCGACGAGACCCACACGCTGGTCGGCGCCGGTGGCGCGGCCGGCACG
GGGGACGCGGCCAACCTGCTCAAGCCCGCGCTGGCCCGCGGCACGCTGCGCACGGTGGGCGCCACCACCTTTGCCGAGTA
CAAGAAATACATCGAGAAGGACCCGGCGCTGACGCGGCGTTTCCAGAGCGTGCAGGTCGACGAGCCGGATGAAAAACGCG
CCATCCTGATGATGCGCGGCGTCGCCAGCACGATGGAAAAGCACCACCAGGTGCAGATCCTCGACGAGGCGCTGGAGGCC
GCCGTCAAGTTGAGCCACCGCTACATCCCGGCGCGCCAGCTGCCCGACAAGAGCGTCAGCCTGCTCGACACCGCCTGCGC
CCGCGTGGCGGTGAGCCTGCACGCGACGCCGGCCGAGGTCGACGACACGCGCAAGCGCATCGAGGCGCTCGAGACCGAGC
TCGGCATCATCGGCCGCGAGCGCGCCATCGGCATCGACGTGCTGGAACGCGAGGCCGATGCATCGCGCCTGCTGGCCGAT
GAACGCGAGCGCCTGGCCCTGCTCGACCAGCGCTGGGCCGAAGAGAAGACGCTGGTCGACGAGCTGCTCGCCCTGCGCGC
GAAGCTGCGTGGCGGCGTGCGGCCGGTCGAAGGCACCGGCAGCGAACTCGAAGCGGCGGTGGCGCCGGTGGCCGAGGGGG
TCGCCGAGCCGGGTCTGAGCGAGGGCGAGCGCGCCGACGCGCTGGCCCGCCTGCGCGAGGTGCAGGCGCAGCTCGCCACG
CTGCAAGGCGAGAGCCCGCTGATCCTGCCCACGGTCGACTACCAGGCGGTGGCCAGCGTGGTCGGCGACTGGACCGGCAT
CCCGGTCGGCCGCATGGCGCGCAACGAGATCGACACCGTGCTCAAGCTGCCCACGCTGCTGGCCCAGCGCGTGATCGGCC
AGGACCACGCGATGGAGATGATCGCCAAGCGCATCCAGACCTCGCGCGCCGGCCTCGACAACCCGGGCAAGCCGATCGGC
GTCTTCATGCTCGCCGGCACTTCGGGCGTCGGCAAGACCGAAACCGCGCTGGCGCTGGCCGAGGCGCTCTACGGCGGCGA
GCAGAACCTCATCGTCATCAACATGAGCGAGTACCAGGAGGCTCACACCGTGAGCTCGCTCAAAGGCGCGCCACCCGGCT
ACGTCGGCTATGGCGAAGGGGGCGTGCTGACCGAGGCGGTGCGCCGCAAGCCCTACAGCGTGGTGCTGCTCGACGAGGTC
GAGAAGGCCCACCCGGATGTGCACGAGCTGTTCTTCCAGGTCTTCGACAAGGGCTTCATGGAAGACGGCGAAGGCCGCGT
GATCGACTTCAAGAACACCCTGATCCTGCTGACCACCAACGCCGGCACCGAGCTGATCTCGGCGCTGTGCCGCGACCCCG
CGCGCATGCCCGACCCGGAGGGCATGGCGAAGGCGCTGCGCCAGCCGCTGCTGGAGATCTTTCCGCCCGCGCTGCTCGGC
CGGCTGGTGGCGATCCCGTATTACCCGCTCAGCGACGAGATGCTCGGGCGCATCGTCAAGCTGCAGCTGGAGCGCATCCG
CAAGCGGGTGGAGACGCGCTACAAGATCCCGTTCGAGTATGGCGACGACGTGGTCGAGCTGGTGGTCAGCCGCTGCACCG
AGAGCGAGTCGGGCGGGCGGATGATCGACGCGATCCTGACCAACACGATGCTGCCGGACATCAGCCGCGAGTTCCTGAAT
CGCATGCTCGATGGCACGCCGATCGAGCGGGTGGAGGTGCAGGTCAGCGAAGGCAATTTCGCCTACGGCTTCGGGCCCGA
CACGGCCGCGCCCGCACGCGATGAACCCTGA

Protein sequence :
MTEISRTALFGKLDPLAYKAIEGATVFCKMRGNPYVELQHWLAQILNTPDSDLHRIIRHYELDSAALAADLTRSLDRLPR
GASSISDFSTFVLDAVERAWIYGSLMFGERQIRTGHLLIGLLKTPSLRNVLLSISKQFERVKLDDLADRFASLLAASPEQ
SQGASDSGAAPGEASDAIPPAAMGKQEALKRFTTDLTEQARAGKMDPIVGRDDEIRQVVDILMRRRQNNPILVGEAGVGK
TAVVEGFAQRIARGDVPPALKEVQLLALDVGLLQAGASMKGEFEQRLRSVIEEVQASPKPIILFVDETHTLVGAGGAAGT
GDAANLLKPALARGTLRTVGATTFAEYKKYIEKDPALTRRFQSVQVDEPDEKRAILMMRGVASTMEKHHQVQILDEALEA
AVKLSHRYIPARQLPDKSVSLLDTACARVAVSLHATPAEVDDTRKRIEALETELGIIGRERAIGIDVLEREADASRLLAD
ERERLALLDQRWAEEKTLVDELLALRAKLRGGVRPVEGTGSELEAAVAPVAEGVAEPGLSEGERADALARLREVQAQLAT
LQGESPLILPTVDYQAVASVVGDWTGIPVGRMARNEIDTVLKLPTLLAQRVIGQDHAMEMIAKRIQTSRAGLDNPGKPIG
VFMLAGTSGVGKTETALALAEALYGGEQNLIVINMSEYQEAHTVSSLKGAPPGYVGYGEGGVLTEAVRRKPYSVVLLDEV
EKAHPDVHELFFQVFDKGFMEDGEGRVIDFKNTLILLTTNAGTELISALCRDPARMPDPEGMAKALRQPLLEIFPPALLG
RLVAIPYYPLSDEMLGRIVKLQLERIRKRVETRYKIPFEYGDDVVELVVSRCTESESGGRMIDAILTNTMLPDISREFLN
RMLDGTPIERVEVQVSEGNFAYGFGPDTAAPARDEP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 0.0 53
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 4e-140 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 6e-140 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lcho_4084 YP_001793101.1 type VI secretion ATPase VFG2076 Protein 0.0 76
Lcho_4084 YP_001793101.1 type VI secretion ATPase VFG2084 Protein 3e-150 43