Gene Information

Name : Lcho_3069 (Lcho_3069)
Accession : YP_001792094.1
Strain : Leptothrix cholodnii SP-6
Genome accession: NC_010524
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 3395990 - 3397270 bp
Length : 1281 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: dar:Daro_2440 UDP-glucose/GDP-mannose dehydrogenase:6-phosphogluconate d

DNA sequence :
ATGACAACTATTGCTGTCGTGGGTTTGGGCTATGTCGGCCTGCCCCTTGCCGTCGAGTTCGGCAAGAAGCACCGCACCAT
CGGTTTTGACCTGTCGCAGGCCAAGATCGATGCGTACAAGCGCCATGTCGATCCGACAGGCGAGGTCAGCACCGAGTTGC
TGCAGTCGTCGACCGGGCTCGAGCCCACGACCGACGCCTCGGCGCTGCGCGAGGCCGATTTCGTGGTGGTCGCCGTGCCG
ACGCCGGTCGACGACGCTCACAACCCCGACTTCAGCCCGCTCGTGGGCGCCAGCCGTTCGGTCGGGCGCAACCTCAAGCC
GGGTGCGATCGTGGTCTATGAGTCGACCGTCTACCCCGGTGCGACCGAAGAGGTGTGCATCCCGATCCTGGAAAAAGAGT
CCGGCCTCAAGTGGCAGAAGGACTTCTGGGTCGGCTATTCGCCCGAGCGCATCAACCCGGGCGACAAGCTGCACACGCTG
ACCACCATCACCAAGGTGGTGTCGGGCGACTGCCCCGAAACCTTGGCCAAGGTGGCCGATGTCTACGGCAGCATCATCAC
CGCCGGGGTCTACAAGGCCAGCTCGATCAAGGTGGCCGAGGCCGCCAAGGTGATCGAGAACACCCAGCGCGACCTCAACA
TCGCGCTCGTCAACGAGCTGTCGCTGATCTTCCACCGCATCGGCATCGACACCACCGAGGTGCTGCAGGCTGCGGGCACC
AAGTGGAACTTCCTGCCGTTCCGCCCGGGCCTGGTCGGCGGCCATTGCATCGGCGTCGATCCGTACTACCTGACCAACAA
GGCCGAACGGATGGGCTATCACCCGCAGGTGATCCTGGCCGGGCGGCGCATCAACGACGGCATGGGCAAGTTCATCGCCG
AGCAGACCGTCAAGGAGCTGATCCGCCTGGGCGCGCCGGTCAAGGGTGCGCACGTGATCGTGCAGGGCCTGACCTTCAAG
GAAAACTGCCCCGACCTGCGCAACTCCAAGGTCATCGACGTGATCCGCGAGCTCGAGACCTACGGCGTGACGGTGCACGT
GCACGACCCGGTGGCCGACCCGGCCGAGGCGATGCACGAATACGGCGTCGAGCTGGTCGAGTGGGCGCACCTGCCCCGCG
CCAACGCGATCGTCGCGGCGGTGGCCCACGATGAACTGGCGCATCGCCCGATCGACGCCCTGCTGACCAAGCTGGCGCCG
GGCGGCCTGTACGTCGACGTCAAGGCCCAGGCCGACCGTGCCGCGCTGGAGGCACGTGGCATCCACGTGTGGCGCCTGTG
A

Protein sequence :
MTTIAVVGLGYVGLPLAVEFGKKHRTIGFDLSQAKIDAYKRHVDPTGEVSTELLQSSTGLEPTTDASALREADFVVVAVP
TPVDDAHNPDFSPLVGASRSVGRNLKPGAIVVYESTVYPGATEEVCIPILEKESGLKWQKDFWVGYSPERINPGDKLHTL
TTITKVVSGDCPETLAKVADVYGSIITAGVYKASSIKVAEAAKVIENTQRDLNIALVNELSLIFHRIGIDTTEVLQAAGT
KWNFLPFRPGLVGGHCIGVDPYYLTNKAERMGYHPQVILAGRRINDGMGKFIAEQTVKELIRLGAPVKGAHVIVQGLTFK
ENCPDLRNSKVIDVIRELETYGVTVHVHDPVADPAEAMHEYGVELVEWAHLPRANAIVAAVAHDELAHRPIDALLTKLAP
GGLYVDVKAQADRAALEARGIHVWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 1e-107 58
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-99 54
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-99 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lcho_3069 YP_001792094.1 nucleotide sugar dehydrogenase VFG0431 Protein 6e-100 54